World's Best Scientists 2026 revealed!
Claire-Anne Siegrist

Claire-Anne Siegrist

D-Index & Metrics

Immunology

D-Index
90
Citations
26275
World Ranking
1085
National Ranking
27

Medicine

D-Index
90
Citations
26276
World Ranking
12326
National Ranking
167

Overview

Claire-Anne Siegrist is affiliated with the University of Geneva in Switzerland. Their research primarily spans the field of medicine, with a strong focus on infectious diseases. The subfields of study include infectious diseases, immunology, epidemiology, neurology, and genetics.

The scientist's work covers various topics related to viral infections and immune responses, particularly focusing on SARS-CoV-2 and COVID-19 research. Main topics include:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Viral Infections and Outbreaks Research
  • SARS-CoV-2 detection and testing
  • Viral Infections and Vectors
  • Immunotherapy and Immune Responses
  • Respiratory viral infections research

Key publications by Claire-Anne Siegrist include:

  • "Validation of a commercially available SARS-CoV-2 serological immunoassay," 2020, Clinical Microbiology and Infection
  • "Antibody persistence in the first 6 months following SARS-CoV-2 infection among hospital workers: a prospective longitudinal study," 2021, Clinical Microbiology and Infection
  • "Neutralization capacity of antibodies elicited through homologous or heterologous infection or vaccination against SARS-CoV-2 VOCs," 2022, Nature Communications
  • "Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity," 2021, Cell Reports
  • "Omicron-Specific Cytotoxic T-Cell Responses After a Third Dose of mRNA COVID-19 Vaccine Among Patients With Multiple Sclerosis Treated With Ocrelizumab," 2022, JAMA Neurology

The scientist frequently publishes in venues that include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Clinical Microbiology and Infection
  • European Journal of Clinical Investigation
  • Nature Communications

Collaborations are notable in Claire-Anne Siegrist's research, with frequent coauthors being:

  • Christiane S. Eberhardt
  • Benjamin Meyer
  • Donata Medaglini
  • Laurent Kaiser
  • Angela Huttner

Best Publications

  • Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA

    Viktor Steimle;Claire Anne Siegrist;Annick Mottet;Barbara Lisowska-Grospierre

  • Neonatal and early life vaccinology.

    Claire-Anne Siegrist

  • B-cell responses to vaccination at the extremes of age.

    Claire Anne Siegrist;Richard Aspinall

  • CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice.

    Cynthia L. Brazolot Millan;Risini Weeratna;Arthur M. Krieg;Claire-Anne Siegrist

  • Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe

    Selidji T Agnandji;Angela Huttner;Madeleine E Zinser;Patricia Njuguna

  • Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants.

    Claire Anne Siegrist

  • Challenges in infant immunity: implications for responses to infection and vaccines

    Mercy Prabhudas;Becky Adkins;Hayley Gans;Christopher King

  • Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials

    Roman Prymula;Claire-Anne Siegrist;Roman Chlibek;Helena Zemlickova

  • Revisiting Human IL-12Rβ1 Deficiency: A Survey of 141 Patients From 30 Countries

    Ludovic de Beaucoudrey;Arina Samarina;Arina Samarina;Arina Samarina;Jacinta Bustamante;Jacinta Bustamante;Aurélie Cobat;Aurélie Cobat

  • APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

    Elodie Belnoue;Maria Pihlgren;Tracy L. McGaha;Chantal Tougne

  • Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2‐biased pattern which persists after adult boosting

    Christy Barrios;Pierre Brawand;Monika Berney;Christian Brandt

  • Recovery of immune reactivity after T-cell-depleted bone marrow transplantation depends on thymic activity.

    Etienne Roux;Florence Dumont-Girard;Michel Starobinski;Claire-Anne Siegrist

  • TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts

    Claudia Bossen;Teresa G. Cachero;Aubry Tardivel;Karine Ingold

  • Glycoconjugate vaccines and immune interference: A review

    Ron Dagan;Jan Poolman;Claire-Anne Siegrist

  • Low Penetrance, Broad Resistance, and Favorable Outcome of Interleukin 12 Receptor β1 Deficiency Medical and Immunological Implications

    Claire Fieschi;Stéphanie Dupuis;Emilie Catherinot;Jacqueline Feinberg

  • Influence of Mycobacterium bovis bacillus Calmette-Guérin on antibody and cytokine responses to human neonatal vaccination

    Martin O. C. Ota;Johan Vekemans;Susanna E. Schlegel-Haueter;Katherine Fielding

  • The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial

    Angela Huttner;Julie-Anne Dayer;Sabine Yerly;Christophe Combescure

  • Importance of background rates of disease in assessment of vaccine safety during mass immunisation with pandemic H1N1 influenza vaccines.

    Steven Black;Juhani Eskola;Claire Anne Siegrist;Neal Halsey

  • Maternal Immunization Earlier in Pregnancy Maximizes Antibody Transfer and Expected Infant Seropositivity Against Pertussis

    Christiane S. Eberhardt;Geraldine Blanchard-Rohner;Barbara Lemaître;Meriem Boukrid

  • Prevention of vertical HIV transmission: additive protective effect of elective Cesarean section and zidovudine prophylaxis. Swiss Neonatal HIV Study Group.

    Christian Kind;Christoph Rudin;Claire-Anne Siegrist;Claire-Anne Wyler

Frequent Co-Authors

Paul-Henri Lambert
Paul-Henri Lambert University of Geneva
Laurent Kaiser
Laurent Kaiser Hôpitaux Universitaires de Genève
Daniel D. Pinschewer
Daniel D. Pinschewer University of Basel
Sabine Yerly
Sabine Yerly University of Geneva
Bernard Mach
Bernard Mach University of Geneva
Arnaud Marchant
Arnaud Marchant Université Libre de Bruxelles
Andrew J. Pollard
Andrew J. Pollard University of Oxford
Melanie J. Newport
Melanie J. Newport Brighton and Sussex Medical School
Isabella Eckerle
Isabella Eckerle University of Geneva
Didier Pittet
Didier Pittet University of Geneva

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