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John D. Elsworth

John D. Elsworth

D-Index & Metrics

Neuroscience

D-Index
72
Citations
17476
World Ranking
2314
National Ranking
1097

Overview

John D. Elsworth is affiliated with Yale University in the United States. Their research focuses on biochemistry, genetics, and molecular biology, with significant contributions also in medicine and neuroscience. The scientist's work covers several subfields, including molecular biology, neurology, clinical biochemistry, biochemistry, and physiology.

Their research topics span multiple areas, notably:

  • Paraoxonase enzyme and polymorphisms
  • Coenzyme Q10 studies and effects
  • Biochemical acid research studies
  • Mitochondrial function and pathology
  • Adipose tissue and metabolism
  • Parkinson's disease mechanisms and treatments
  • Genetic neurodegenerative diseases

John D. Elsworth has authored papers published in journals including Pharmacology & Therapeutics, Journal of Neural Transmission, Life Sciences, Experimental Neurology, and Neuropathology and Applied Neurobiology. Examples of recent publications are:

  • Parkinson's disease treatment: past, present, and future, 2020, Journal of Neural Transmission
  • PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders, 2020, Pharmacology & Therapeutics
  • An updated insight into the molecular pathogenesis, secondary complications and potential therapeutics of COVID-19 pandemic, 2020, Life Sciences
  • Pioglitazone activates paraoxonase-2 in the brain: A novel neuroprotective mechanism, 2020, Experimental Neurology
  • Intrathecal amyloid-beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's disease, 2022, Neuropathology and Applied Neurobiology

Frequent publication venues for the scientist's work include:

  • Free Radical Biology and Medicine
  • UNC Libraries
  • Pharmacology & Therapeutics
  • Journal of Neural Transmission
  • Life Sciences

John D. Elsworth collaborates regularly with several coauthors. Notable among them are:

  • Sumit Jamwal
  • Jennifer K. Blackburn
  • Robert H. Roth
  • Matthew S Lawrence
  • Puneet Kumar

Best Publications

  • Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

    Alfonso Abizaid;Zhong-Wu Liu;Zane Bruce Andrews;Marya Shanabrough

  • Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with parkinson’s disease

    Dennis D. Spencer;Dennis D. Spencer;Richard J. Robbins;Frederick Naftolin;Frederick Naftolin;Kenneth L. Marek;Kenneth L. Marek

  • Enduring Cognitive Deficits and Cortical Dopamine Dysfunction in Monkeys After Long-Term Administration of Phencyclidine

    J. David Jentsch;D. Eugene Redmond;John D. Elsworth;Jane R. Taylor

  • Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing

    Christina D. Camell;Jil Sander;Olga Spadaro;Aileen Lee

  • Dopamine Synthesis, Uptake, Metabolism, and Receptors: Relevance to Gene Therapy of Parkinson's Disease

    John D. Elsworth;Robert H. Roth

  • Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells

    D. Eugene Redmond;Kimberly B. Bjugstad;Yang D. Teng;Vaclav Ourednik

  • DEPRENYL IN PARKINSON'S DISEASE

    A.J. Lees;L.J. Kohout;K.M. Shaw;G.M. Stern

  • MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

    Brooke H. Miller;Zane Zeier;Li Xi;Thomas A. Lanz

  • Cocaethylene: A neuropharmacologically active metabolite assciated with concurrent cocaine-ethanol ingestion

    P. Jatlow;J. D. Elsworth;C. W. Bradberry;Gail D. Winger

  • Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory.

    Csaba Leranth;Robert H. Roth;John D. Elsworth;Frederick Naftolin

  • Ghrelin Promotes and Protects Nigrostriatal Dopamine Function via a UCP2-Dependent Mitochondrial Mechanism

    Zane Bruce Andrews;Derek Erion;Rudolph Beiler;Zhong-Wu Liu

  • Deprenyl administration in man: A selective monoamine oxidase B inhibitor without the ‘cheese effect’

    J. D. Elsworth;Vivette Glover;G. P. Reynolds;M. Sandler

  • FETAL NEURONAL GRAFTS IN MONKEYS GIVEN METHYLPHENYLTETRAHYDROPYRIDINE

    D.Eugene Redmond;RobertH. Roth;JohnD. Elsworth;JohnR. Sladek

  • In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector

    MJ During;RJ Samulski;JD Elsworth;MG Kaplitt

  • Spontaneous blink rates correlate with dopamine levels in the caudate nucleus of MPTP-treated monkeys.

    J.R. Taylor;J.D. Elsworth;M.S. Lawrence;J.R. Sladek

  • The predator odor, TMT, displays a unique, stress-like pattern of dopaminergic and endocrinological activation in the rat

    Bret A. Morrow;Andy J. Redmond;Robert H. Roth;John D. Elsworth

  • Molecular and cellular reorganization of neural circuits in the human lineage

    André M. M. Sousa;Ying Zhu;Mary Ann Raghanti;Robert R. Kitchen

  • The role of mesoprefrontal dopamine neurons in the acquisition and expression of conditioned fear in the rat.

    B.A. Morrow;J.D. Elsworth;A.M. Rasmusson;R.H. Roth

  • Endometrial stem cell transplantation restores dopamine production in a Parkinson’s disease model

    Erin F. Wolff;Xiao-Bing Gao;Katherine V. Yao;Zane B. Andrews

  • Cocaine and Cocaethylene: Microdialysis Comparison of Brain Drug Levels and Effects on Dopamine and Serotonin

    Charles W. Bradberry;J. B. Nobiletti;J. D. Elsworth;B. Murphy

  • Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates.

    Robert B. Innis;Robert T. Malison;Mohammed Al-Tikriti;Paul B. Hoffer

Frequent Co-Authors

Jane R. Taylor
Jane R. Taylor Yale University
John R. Sladek
John R. Sladek University of Colorado Denver
R. H. Roth
R. H. Roth Yale University
Csaba Leranth
Csaba Leranth Yale University
Timothy J. Collier
Timothy J. Collier Michigan State University
Ariel Y. Deutch
Ariel Y. Deutch Vanderbilt University
J. David Jentsch
J. David Jentsch Binghamton University
Yang D. Teng
Yang D. Teng Spaulding Rehabilitation Hospital
Tibor Hajszan
Tibor Hajszan Biological Research Centre
Sabrina Diano
Sabrina Diano Columbia University

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