2026 Christian Gilissen: Genetics Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Genetics	91	1033	975	34	34	325	31362

Overview

Christian Gilissen is affiliated with Radboud University in the Netherlands and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research focuses primarily on genetics and molecular biology, with additional work related to cancer research, immunology, and pathology and forensic medicine.

The scientist's research addresses a range of topics, including:

Genomics and Rare Diseases
Genomic variations and chromosomal abnormalities
Genetics and Neurodevelopmental Disorders
Cancer Genomics and Diagnostics
Retinal Development and Disorders
RNA modifications and cancer
Genetic factors in colorectal cancer

Gilissen has authored multiple papers published in various scientific journals. Notable recent papers include:

"Presence of Genetic Variants Among Young Men With Severe COVID-19," published in 2020 in JAMA
"Resolving the dark matter of ABCA4 for 1054 Stargardt disease probands through integrated genomics and transcriptomics," published in 2020 in Genetics in Medicine
"Structural Variants Create New Topological-Associated Domains and Ectopic Retinal Enhancer-Gene Contact in Dominant Retinitis Pigmentosa," published in 2020 in The American Journal of Human Genetics
"Recommendations for whole genome sequencing in diagnostics for rare diseases," published in 2022 in European Journal of Human Genetics
"Solve-RD: systematic pan-European data sharing and collaborative analysis to solve rare diseases," published in 2021 in European Journal of Human Genetics

Frequent publication venues for Gilissen's work include:

bioRxiv (Cold Spring Harbor Laboratory)
European Journal of Human Genetics
Genetics in Medicine
The American Journal of Human Genetics
Genome Medicine

Collaborations form a significant part of Gilissen's research activity. Their frequent co-authors include:

Lisenka E.L.M. Vissers
Alexander Hoischen
Rolph Pfundt
Han G. Brunner
Wouter Steyaert

The number of publications attributed to Gilissen reflects a focus on genetic disorders and complex genomic analyses, with particular attention to rare diseases. The integration of genomics and transcriptomics is a recurring methodological approach, as seen in their research on retinal disorders and whole genome sequencing diagnostics.

This body of work illustrates Gilissen's engagement with cutting-edge genetic research relevant to understanding and diagnosing complex human diseases.

Best Publications

Diagnostic Exome Sequencing in Persons With Severe Intellectual Disability

Joep de Ligt;Marjolein H. Willemsen;Bregje W. M. van Bon;Tjitske Kleefstra

1986
Citations
Genome sequencing identifies major causes of severe intellectual disability

Christian Gilissen;Jayne Y. Hehir-Kwa;Djie Tjwan Thung;Maartje van de Vorst

1228
Citations
A de novo paradigm for mental retardation.

Lisenka E L M Vissers;Joep de Ligt;Christian Gilissen;Irene Janssen

948
Citations
Genetic studies in intellectual disability and related disorders

Lisenka E. L. M. Vissers;Christian Gilissen;Joris A. Veltman;Joris A. Veltman

803
Citations
Presence of Genetic Variants Among Young Men With Severe COVID-19.

Caspar I. van der Made;Annet Simons;Janneke Schuurs-Hoeijmakers;Guus van den Heuvel

767
Citations
STAT1 Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

Frank L. van de Veerdonk;Theo S. Plantinga;Alexander Hoischen;Sanne P. Smeekens

709
Citations
De novo mutations of SETBP1 cause Schinzel-Giedion syndrome

Alexander Hoischen;Bregje W M van Bon;Christian Gilissen;Peer Arts

583
Citations
Disease gene identification strategies for exome sequencing

Christian Gilissen;Alexander Hoischen;Han G Brunner;Joris A Veltman

583
Citations
A recent bottleneck of Y chromosome diversity coincides with a global change in culture

Monika Karmin;Monika Karmin;Lauri Saag;Lauri Saag;Mário Vicente;Melissa A. Wilson Sayres;Melissa A. Wilson Sayres

514
Citations
Evidence for 28 genetic disorders discovered by combining healthcare and research data

J Kaplanis;K E Samocha;L Wiel;Z Zhang

473
Citations
Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability

Stefan H Lelieveld;Margot R F Reijnders;Rolph Pfundt;Helger G Yntema

464
Citations
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Catherine A. Brownstein;Alan H. Beggs;Nils Homer;Barry Merriman

435
Citations
A post-hoc comparison of the utility of sanger sequencing and exome sequencing for the diagnosis of heterogeneous diseases

Kornelia Neveling;Ilse Feenstra;Christian Gilissen;Lies H. Hoefsloot

430
Citations
Exome Sequencing Identifies Truncating Mutations in Human SERPINF1 in Autosomal-Recessive Osteogenesis Imperfecta

Jutta Becker;Oliver Semler;Christian Gilissen;Yun Li

397
Citations
A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer

Robbert D A Weren;Marjolijn J L Ligtenberg;C Marleen Kets;Richarda M de Voer

392
Citations
Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome

Gijs W E Santen;Emmelien Aten;Yu Sun;Rowida Almomani

391
Citations
Improved exome prioritization of disease genes through cross-species phenotype comparison.

Peter N. Robinson;Sebastian Köhler;Anika Oellrich;Sanger Mouse Genetics

357
Citations
Unlocking Mendelian disease using exome sequencing

Christian Gilissen;Alexander Hoischen;Han G Brunner;Joris A Veltman

344
Citations
Exome Sequencing Identifies WDR35 Variants Involved in Sensenbrenner Syndrome

Christian Gilissen;Heleen H. Arts;Alexander Hoischen;Liesbeth Spruijt

339
Citations
Next-generation genetic testing for retinitis pigmentosa.

Kornelia Neveling;Rob W.J. Collin;Christian Gilissen;Ramon A.C. van Huet

339
Citations

Frequent Co-Authors

Joris A. Veltman University of Edinburgh

Alexander Hoischen Radboud University

Han G. Brunner Radboud University

Lisenka E.L.M. Vissers Radboud University

Rolph Pfundt Radboud University

Helger G. Yntema Radboud University

Tjitske Kleefstra Erasmus University Rotterdam

Hans van Bokhoven Radboud University

Frans P.M. Cremers Radboud University

Arjan P.M. de Brouwer Radboud University

External Links

Personal website of Christian Gilissen

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