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C. Peter Downes

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
36372
World Ranking
3431
National Ranking
259

C. Peter Downes publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where C. Peter Downes sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 206 publications — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

C. Peter Downes D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where C. Peter Downes sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 83 D-Index — 83rd percentile

83% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 1991 - Fellow of the Royal Society of Edinburgh

Overview

C. Peter Downes is affiliated with the University of Dundee in the United Kingdom and has contributed primarily to the fields of Biochemistry, Genetics and Molecular Biology. Their research output includes a significant focus on Molecular Biology, Physiology, and Surgery as subfields. The core scientific topics frequently addressed in their work consist of Protein Kinase Regulation and GTPase Signaling, PI3K/AKT/mTOR signaling in cancer, Adenosine and Purinergic Signaling, Cell death mechanisms and regulation, Metabolism, Diabetes, and Cancer, Pancreatic function and diabetes, and Calcium signaling and nucleotide metabolism.

Recent publications by C. Peter Downes include the following papers:

  • A receptor and G-protein-regulated polyphosphoinositide-specific phospholipase C from turkey erythrocytes. II. P2Y-purinergic receptor and G-protein-mediated regulation of the purified enzyme reconstituted with turkey erythrocyte ghosts., 2021, UNC Libraries
  • A receptor and G-protein-regulated polyphosphoinositide-specific phospholipase C from turkey erythrocytes. I. Purification and properties., 2021, UNC Libraries
  • Time-dependent inhibition of phospholipase C β -catalysed phosphoinositide hydrolysis: a comparison of different assays, 2020, UNC Libraries
  • Kinetics and activation of phospholipase C by P2Y purinergic agonists and guanine nucleotides, 2021, UNC Libraries

Frequent coauthors in their research work include:

  • Nicholas R. Leslie
  • Gary L Waldo
  • T. Kendall Harden
  • Jason E. Schaffer
  • Justin J. Miller

The primary venue for their publications has been UNC Libraries, where they have contributed to at least four works. Their scientific contributions have culminated in recognition such as the Fellowship of the Royal Society of Edinburgh awarded in 1991.

Best Publications

  • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

    Dario R. Alessi;Stephen R. James;C.Peter Downes;Andrew B. Holmes

  • Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands.

    M J Berridge;C P Downes;M R Hanley

  • Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides.

    M J Berridge;R M C Dawson;C P Downes;J P Heslop

  • Neural and developmental actions of lithium: A unifying hypothesis

    Michael J. Berridge;C.Peter Downes;Michael R. Hanley

  • The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.

    Laura S Harrington;Greg M Findlay;Alexander Gray;Tatiana Tolkacheva

  • Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate.

    M Whitman;C P Downes;M Keeler;T Keller

  • Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

    S Dowler;R A Currie;D G Campbell;M Deak

  • Redox regulation of PI 3-kinase signalling via inactivation of PTEN

    Nick R Leslie;Deborah Bennett;Yvonne E Lindsay;Hazel Stewart

  • Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones.

    J A Creba;C P Downes;P T Hawkins;G Brewster

  • The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane

    C P Downes;M C Mussat;R H Michell

  • The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions.

    Robert Hall Michell;C. J. Kirk;Lynne M. Jones;C. P. Downes

  • PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2

    Anudharan Balendran;Antonio Casamayor;Maria Deak;Andrew Paterson

  • A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation

    Elizabeth Clayton;Giuseppe Bardi;Sarah E. Bell;David Chantry

  • PTEN function: how normal cells control it and tumour cells lose it

    Nick R Leslie;C Peter Downes

  • PTEN: The down side of PI 3-kinase signalling.

    Nick R. Leslie;C.Peter Downes

  • Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.

    R A Currie;K S Walker;A Gray;M Deak

  • Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN

    Lisa Patel;Ian Pass;Phil Coxon;C.Peter Downes

  • Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

    Stephen R. James;C. Peter Downes;Roy Gigg;Simon J. A. Grove

  • Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.

    Stephen A Watt;Gursant Kular;Ian N Fleming;C Peter Downes

  • Inositol 1,3,4,5-tetrakisphosphate and not phosphatidylinositol 3,4-bisphosphate is the probable precursor of inositol 1,3,4-trisphosphate in agonist-stimulated parotid gland.

    C P Downes;P T Hawkins;R F Irvine

Frequent Co-Authors

Nick R. Leslie
Nick R. Leslie Heriot-Watt University
John M. Lucocq
John M. Lucocq University of St Andrews
Dario R. Alessi
Dario R. Alessi University of Dundee
Anthony D. Whetton
Anthony D. Whetton University of Manchester
Maria Deak
Maria Deak University of Dundee
Philip Cohen
Philip Cohen University of Dundee
Alan R. Prescott
Alan R. Prescott University of Dundee
Michael L. J. Ashford
Michael L. J. Ashford University of Dundee
Eric Hajduch
Eric Hajduch European Association for the Study of Diabetes
Andrew B. Holmes
Andrew B. Holmes University of Melbourne

External Links

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Best Scientists Citing C. Peter Downes

Dario R. Alessi

Dario R. Alessi

University of Dundee

Publications: 78

Bart Vanhaesebroeck

Bart Vanhaesebroeck

University College London

Publications: 56

Brian A. Hemmings

Brian A. Hemmings

Friedrich Miescher Institute

Publications: 55

Nick R. Leslie

Nick R. Leslie

Heriot-Watt University

Publications: 45

Lewis C. Cantley

Lewis C. Cantley

Harvard University

Publications: 38

Gordon B. Mills

Gordon B. Mills

Oregon Health & Science University

Publications: 32

Stephen B. Shears

Stephen B. Shears

National Institutes of Health

Publications: 32

Klaus Okkenhaug

Klaus Okkenhaug

University of Cambridge

Publications: 32

Alex Toker

Alex Toker

Beth Israel Deaconess Medical Center

Publications: 30

Tamas Balla

Tamas Balla

National Institutes of Health

Publications: 29

Philip Cohen

Philip Cohen

University of Dundee

Publications: 29

David A. Fruman

David A. Fruman

University of California, Irvine

Publications: 28

Phillip T. Hawkins

Phillip T. Hawkins

Babraham Institute

Publications: 28

Peter J. Parker

Peter J. Parker

The Francis Crick Institute

Publications: 28

James A. McCubrey

James A. McCubrey

East Carolina University

Publications: 28

Pier Paolo Pandolfi

Pier Paolo Pandolfi

Beth Israel Deaconess Medical Center

Publications: 26

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