World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
55
Citations
14305
World Ranking
2254
National Ranking
1112

Overview

Brian A Walker is affiliated with Indiana University - Purdue University Indianapolis in the United States. Their primary research fields encompass Medicine and Biochemistry, Genetics and Molecular Biology. Within these, their notable subfields include Molecular Biology, Hematology, Oncology, Cancer Research, and Plant Science.

Walker's research concentrates largely on Multiple Myeloma Research and Treatments, supported by extensive work in Protein Degradation and Inhibitors. Additional research topics include Cancer Genomics and Diagnostics, Peptidase Inhibition and Analysis, Chromosomal and Genetic Variations, Glycosylation and Glycoproteins Research, and Cancer Mechanisms and Therapy.

Some of Walker's recent published papers feature:

  • The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma, 2021, Nature Communications
  • Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities, 2021, Nature Communications
  • Long-term outcomes after autologous stem cell transplantation for multiple myeloma, 2020, Blood Advances
  • Genomic Classification and Individualized Prognosis in Multiple Myeloma, 2024, Journal of Clinical Oncology
  • Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials, 2020, PLoS Medicine

Walker has collaborated frequently with several co-authors, including Gareth J. Morgan, Faith E. Davies, Enze Liu, Eileen M. Boyle, and Parvathi Sudha. These collaborations highlight a focused network within the hematology and oncology research community.

The scientist's work is published across a range of venues, with a concentration in:

  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Lymphoma Myeloma & Leukemia
  • Nature Communications
  • Leukemia

Best Publications

  • The chicken B locus is a minimal essential major histocompatibility complex

    Jim Kaufman;Sarah Milne;Thomas W. F. Göbel;Brian A. Walker

  • Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma

    Brian A. Walker;Eileen M. Boyle;Christopher P. Wardell;Alex Murison

  • A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms

    Gane Ka Shu Wong;Gane Ka Shu Wong;Gane Ka Shu Wong;Bin Liu;Jun Wang;Jun Wang;Yong Zhang;Yong Zhang

  • A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

    Brian A. Walker;Paola E. Leone;Laura Chiecchio;Nicholas J. Dickens

  • Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.

    Brian A. Walker;Konstantinos Mavrommatis;Christopher P. Wardell;T. Cody Ashby

  • A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.

    K D Boyd;F M Ross;L Chiecchio;G P Dagrada

  • APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma

    Brian A Walker;Christopher P Wardell;Alex Murison;Eileen M Boyle

  • Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

    L. Rasche;S. S. Chavan;O. W. Stephens;P. H. Patel

  • Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms.

    Brian A Walker;Christopher P Wardell;Lorenzo Melchor;Annamaria Brioli

  • Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.

    Brian A. Walker;Christopher P. Wardell;Lorenzo Melchor;Sanna Hulkki

  • Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

    L Melchor;A Brioli;C P Wardell;A Murison

  • Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients

    V Shah;A L Sherborne;B A Walker;D C Johnson

  • Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma.

    Brian A. Walker;Paola E. Leone;Paola E. Leone;Paola E. Leone;Matthew W. Jenner;Matthew W. Jenner;Matthew W. Jenner;Cheng Li;Cheng Li;Cheng Li

  • Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma

    Niels Weinhold;Cody Ashby;Leo Rasche;Shweta S. Chavan

  • Mapping of Chromosome 1p Deletions in Myeloma Identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as Being Genes in Regions Associated with Adverse Survival

    KD Boyd;FM Ross;BA Walker;CP Wardell

  • Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

    B A Walker;C P Wardell;A Brioli;E Boyle

  • Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.

    Brian A. Walker;Christopher P. Wardell;David C. Johnson;Martin F. Kaiser

  • Gene organisation determines evolution of function in the chicken MHC.

    Jim Kaufman;Jansen Jacob;Jain Shaw;Brain Walker

  • Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

    Peter Broderick;Daniel Chubb;David C Johnson;Niels Weinhold

  • Apobec Family Mutational Signatures Are Associated with Poor Prognosis Translocations in Multiple Myeloma

    Brian A Walker;Brian A Walker;Christopher P Wardell;Alexander Murison;Eileen M Boyle

Frequent Co-Authors

Gareth J. Morgan
Gareth J. Morgan Boston University
Faith E. Davies
Faith E. Davies New York University Langone Medical Center
Frits van Rhee
Frits van Rhee University of Arkansas for Medical Sciences
Maurizio Zangari
Maurizio Zangari University of Arkansas for Medical Sciences
Graham Jackson
Graham Jackson University of Newcastle Australia
Walter M Gregory
Walter M Gregory University of Leeds
David Gonzalez
David Gonzalez University of California, San Diego
Bart Barlogie
Bart Barlogie Mount Sinai Hospital
Mark T. Drayson
Mark T. Drayson University of Birmingham
Richard S. Houlston
Richard S. Houlston Institute of Cancer Research

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology can open doors to a wide range of healthcare and research careers, many of which require advanced degrees or certifications. If you’re interested in branching into nursing or related fields, there are several flexible online pathways to consider.

For those starting as registered nurses, an rn to bsn online program is a popular option. Accelerated programs let you earn your Bachelor of Science in Nursing (BSN) in as little as six months, helping professionals upskill quickly. RNs interested in higher clinical roles can also explore rn to np programs online to bridge from an Associate’s degree straight to a Master of Science in Nursing (MSN) and prepare for advanced practice positions.

Prospective nurse practitioners often ask, how long to become nurse practitioner? While timelines vary, online programs can speed up the process, especially for motivated learners. If you’re curious about potential earnings, our in-depth guide to psych np salary details pay rates by state and specialty, helping you plan your future with confidence.

Best Scientists Citing Brian A Walker

Trending Scientists

Recently Published Articles