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Andrew G. Fraser

Andrew G. Fraser

D-Index & Metrics

Genetics

D-Index
50
Citations
34866
World Ranking
3887
National Ranking
149

Overview

Andrew G. Fraser is affiliated with the University of Toronto in Canada. Their research primarily focuses on medicine, with a significant emphasis on hepatology, as well as related subfields such as epidemiology, molecular biology, surgery, and parasitology.

The scientist has contributed to several main topics within their field of study, including:

  • Hepatitis C virus research
  • Liver disease diagnosis and treatment
  • Liver disease and transplantation
  • Hepatocellular carcinoma treatment and prognosis
  • Parasites and host interactions
  • Gastrointestinal bleeding diagnosis and treatment
  • Drug-induced hepatotoxicity and protection

Andrew G. Fraser has published multiple recent papers, illustrating ongoing research in hepatology and associated topics. These include:

  • Clinical effectiveness of pharmacist-led versus conventionally delivered antiviral treatment for hepatitis C virus in patients receiving opioid substitution therapy: a pragmatic, cluster-randomised trial (2020) in The Lancet. Gastroenterology & Hepatology
  • Mortality and morbidity of locally acquired hepatitis E in the national Scottish cohort: a multicentre retrospective study (2020) in Alimentary Pharmacology & Therapeutics
  • Mortality rates among patients successfully treated for hepatitis C in the era of interferon-free antivirals: population based cohort study (2023) in BMJ
  • Performance of models to predict hepatocellular carcinoma risk among UK patients with cirrhosis and cured HCV infection (2021) in JHEP Reports
  • Population impact of direct-acting antiviral treatment on new presentations of hepatitis C-related decompensated cirrhosis: a national record-linkage study (2020) in Gut

The scientist frequently publishes in journals such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alimentary Pharmacology & Therapeutics
  • Frontline Gastroenterology
  • SSRN Electronic Journal
  • Abstracts

Collaboration is a notable element of Andrew G. Fraser's work, with frequent co-authors including:

  • John Dillon
  • Stephen T. Barclay
  • Sharon Hutchinson
  • Peter Hayes
  • Hamish Innes

Best Publications

  • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

    Ravi S. Kamath;Andrew G. Fraser;Andrew G. Fraser;Yan Dong;Gino Poulin

  • Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

    S. D. Bentley;K. F. Chater;A.-M. Cerdeño-Tárraga;G. L. Challis;G. L. Challis

  • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

    Coleen T. Murphy;Steven A. McCarroll;Cornelia I. Bargmann;Andrew Fraser

  • Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

    Andrew G. Fraser;Ravi S. Kamath;Peder Zipperlen;Maruxa Martinez-Campos

  • A Map of the Interactome Network of the Metazoan C. elegans

    Siming Li;Christopher M. Armstrong;Nicolas Bertin;Hui Ge

  • The genome sequence of Schizosaccharomyces pombe

    V. Wood;R. Gwilliam;M.A. Rajandream;M. Lyne

  • A compendium of RNA-binding motifs for decoding gene regulation

    Debashish Ray;Hilal Kazan;Kate B. Cook;Matthew T. Weirauch;Matthew T. Weirauch

  • Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

    Ravi S Kamath;Maruxa Martinez-Campos;Peder Zipperlen;Andrew G Fraser

  • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes

    Kaveh Ashrafi;Francesca Y. Chang;Jennifer L. Watts;Andrew G. Fraser

  • Rates of Behavior and Aging Specified by Mitochondrial Function During Development

    Andrew Dillin;Ao Lin Hsu;Nuno Arantes-Oliveira;Joshua Lehrer-Graiwer

  • A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity.

    Siu Sylvia Lee;Raymond Y. N. Lee;Raymond Y. N. Lee;Andrew G. Fraser;Ravi S. Kamath

  • Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation.

    Delia Garigan;Ao-Lin Hsu;Andrew G Fraser;Ravi S Kamath

  • A License to Kill

    Andrew Fraser;Gerard Evan

  • Genome-Wide RNAi of C. elegans Using the Hypersensitive rrf-3 Strain Reveals Novel Gene Functions

    Femke Simmer;Celine Moorman;Alexander M van der Linden;Ewart Kuijk

  • Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways.

    Ben Lehner;Ben Lehner;Ben Lehner;Catriona Crombie;Julia Tischler;Angelo Fortunato;Angelo Fortunato;Angelo Fortunato

  • Minimizing the risk of reporting false positives in large-scale RNAi screens

    Christophe J Echeverri;Philip A Beachy;Buzz Baum;Michael Boutros

  • Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors

    K. S. Bell;M. Sebaihia;L. Pritchard;L. Pritchard;M. T. G. Holden

  • A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans

    Insuk Lee;Ben Lehner;Ben Lehner;Catriona Crombie;Wendy Wong

  • International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

    Heather J. Cordell;Younghun Han;George F. Mells;Yafang Li

  • CAENORHABDITIS ELEGANS INHIBITOR OF APOPTOSIS PROTEIN (IAP) HOMOLOGUE BIR-1 PLAYS A CONSERVED ROLE IN CYTOKINESIS

    Andrew G. Fraser;Claerwen James;Gerard I. Evan;Michael O. Hengartner

Frequent Co-Authors

Ben Lehner
Ben Lehner Wellcome Sanger Institute
Julie Ahringer
Julie Ahringer University of Cambridge
Gerard I. Evan
Gerard I. Evan The Francis Crick Institute
Edward M. Marcotte
Edward M. Marcotte The University of Texas at Austin
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Calum A. MacRae
Calum A. MacRae Brigham and Women's Hospital
Quaid Morris
Quaid Morris Memorial Sloan Kettering Cancer Center
Thomas R. Gingeras
Thomas R. Gingeras Cold Spring Harbor Laboratory
Philipp Kapranov
Philipp Kapranov Huaqiao University
Ronald H. A. Plasterk
Ronald H. A. Plasterk University of Amsterdam

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