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Biology and Biochemistry

D-Index
48
Citations
21236
World Ranking
18180
National Ranking
1432

Overview

Alan J. Whitmarsh is affiliated with the University of Manchester in the United Kingdom. Their research primarily falls within the broad field of Biochemistry, Genetics and Molecular Biology, with a specialized focus on Molecular Biology. Additional involvement in Oncology and Pulmonary and Respiratory Medicine is noted.

The main topics of their work include:

  • Melanoma and MAPK Pathways
  • Protein Kinase Regulation and GTPase Signaling
  • Viral Infectious Diseases and Gene Expression in Insects
  • HER2/EGFR in Cancer Research
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • PI3K/AKT/mTOR signaling in cancer

Among recent publications authored or co-authored by Alan J. Whitmarsh are:

  • Eukaryotic translation initiation factor 3d regulates stress granule assembly via its RNA binding domain (2025), bioRxiv (Cold Spring Harbor Laboratory)
  • NRF2-mediated persistent adaptation of oesophageal adenocarcinoma cells to HER2 inhibition (2025), Oncogene
  • Paralogous translation factors target distinct mRNAs to differentially regulate tolerance to oxidative stress in yeast (2023), Nucleic Acids Research
  • Inhibiting ERK5 Overcomes Breast Cancer Resistance to Anti-HER2 Therapy By Targeting the G1-S Cell-Cycle Transition (2022), Cancer Research Communications
  • Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5) (2020), International Journal of Molecular Sciences

Frequent co-authors collaborating with Whitmarsh include:

  • Cathy Tournier
  • Wei Zhang
  • Adam J. Pearson
  • Qiuping Xu
  • Emanuele Giurisato

Whitmarsh's work appears regularly in several scientific venues such as:

  • International Journal of Molecular Sciences
  • Cancer Research Communications
  • Nucleic Acids Research
  • Oncogene
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways

    A J Whitmarsh;R J Davis

  • Selective interaction of JNK protein kinase isoforms with transcription factors.

    Shashi Gupta;Tamera Barrett;Alan J. Whitmarsh;Julie Cavanagh

  • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.

    Joel Raingeaud;Alan J. Whitmarsh;Tamera Barrett;Benoit Derijard

  • Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

    D D Yang;C Y Kuan;A J Whitmarsh;A J Whitmarsh;M Rincón

  • Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element

    Alan J. Whitmarsh;Paul Shore;Andrew D. Sharrocks;Roger J. Davis

  • A mammalian scaffold complex that selectively mediates MAP kinase activation

    Alan J. Whitmarsh;Julie Cavanagh;Cathy Tournier;Jun Yasuda

  • Defective T cell differentiation in the absence of Jnk1

    Chen Dong;Derek D. Yang;Mark Allen Wysk;Alan J. Whitmarsh

  • Transcriptional regulation by the MAP kinase signaling cascades

    Shen Hsi Yang;Andrew D. Sharrocks;Alan J. Whitmarsh

  • The JIP group of mitogen-activated protein kinase scaffold proteins

    Jun Yasuda;Alan J. Whitmarsh;Julie Cavanagh;Manoj Sharma

  • Differentiation of CD4+ T Cells to Th1 Cells Requires MAP Kinase JNK2

    Derek D Yang;Dietrich Conze;Alan J Whitmarsh;Tamera Barrett

  • Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors.

    Alan J. Whitmarsh;Shen Hsi Yang;Michael S S Su;Andrew D. Sharrocks

  • Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

    Cathy Tournier;Alan J. Whitmarsh;Julie Cavanagh;Tamera Barrett

  • Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

    Alan J. Whitmarsh;Roger J. Davis

  • MAP kinase signalling cascades and transcriptional regulation.

    Shen Hsi Yang;Andrew D. Sharrocks;Alan J. Whitmarsh

  • A critical role of neural-specific JNK3 for ischemic apoptosis.

    Chia Yi Kuan;Alan J. Whitmarsh;Alan J. Whitmarsh;Derek D. Yang;Derek D. Yang;Guanghong Liao

  • Regulation of transcription factor function by phosphorylation.

    A. J. Whitmarsh;R. J. Davis

  • JNK is required for effector T-cell function but not for T-cell activation

    Chen Dong;Derek D. Yang;Cathy Tournier;Alan J. Whitmarsh

  • Differential targeting of MAP kinases to the ETS‐domain transcription factor Elk‐1

    Shen Hsi Yang;Alan J. Whitmarsh;Roger J. Davis;Andrew D. Sharrocks

  • Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch

    Rebecca J Richardson;Jill Dixon;Saimon Malhotra;Matthew J Hardman

  • The JIP Group of Mitogen-Activated Protein Kinase

    Jun Yasuda;Alan J. Whitmarsh;Julie Cavanagh;Manoj Sharma

Frequent Co-Authors

Roger J. Davis
Roger J. Davis University of Massachusetts Chan Medical School
Richard A. Flavell
Richard A. Flavell Yale University
Andrew D. Sharrocks
Andrew D. Sharrocks University of Manchester
Pasko Rakic
Pasko Rakic Yale University
Mercedes Rincon
Mercedes Rincon University of Vermont
Chen Dong
Chen Dong Tsinghua University
Harry Moore
Harry Moore University of Sheffield
Gabriel G. Haddad
Gabriel G. Haddad University of California, San Diego
Sharon M. Kelly
Sharon M. Kelly University of Glasgow
Jonathan P. Waltho
Jonathan P. Waltho University of Sheffield

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