Guang-Yi Zhang

Overview

Best Publications

• The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation.

  Liang Hui;Dong Sheng Pei;Quan Guang Zhang;Qiu Hua Guan

  164
  Citations

• Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence.

  Dong-Sheng Pei;Xiao-Tian Wang;Yong Liu;Ya-Feng Sun

  161
  Citations

• Critical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injury

  Quan Guang Zhang;Dong Na Wu;Dong Han;Guang Yi Zhang

  130
  Citations

• Diphosphorylation and involvement of extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons

  Qian Jiang;Zhenglin Gu;Guangyi Zhang;Guozhang Jing

  128
  Citations

• Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis

  Unknown

  126
  Citations

• Opposing effects of Bad phosphorylation at two distinct sites by Akt1 and JNK1/2 on ischemic brain injury.

  Xiao-Tian Wang;Dong-Sheng Pei;Jing Xu;Qiu-Hua Guan

  124
  Citations

• NMDA receptor activation results in tyrosine phosphorylation of NMDA receptor subunit 2A(NR2A) and interaction of Pyk2 and Src with NR2A after transient cerebral ischemia and reperfusion.

  Yong Liu;Guangyi Zhang;Can Gao;Xiaoyu Hou

  123
  Citations

• Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation.

  Bei Miao;Xiao Hui Yin;Dong Sheng Pei;Quan Guang Zhang

  115
  Citations

• Nuclear factor κB activation is mediated by NMDA and non-NMDA receptor and L-type voltage-gated Ca2+ channel following severe global ischemia in rat hippocampus

  Wanhua Shen;Chunyi Zhang;Guangyi Zhang

  111
  Citations

• Activation of GABA receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of NR2A by Src after cerebral ischemia and reperfusion

  F. Zhang;C. Li;R. Wang;D. Han

  107
  Citations

• Additive neuroprotection of GABA A and GABA B receptor agonists in cerebral ischemic injury via PI-3K/Akt pathway inhibiting the ASK1-JNK cascade.

  Jing Xu;Chong Li;Xiao-Hui Yin;Guang-Yi Zhang

  105
  Citations

• Neuroprotection of γ-Aminobutyric Acid Receptor Agonists Via Enhancing Neuronal Nitric Oxide Synthase (Ser847) Phosphorylation Through Increased Neuronal Nitric Oxide Synthase and PSD95 Interaction and Inhibited Protein Phosphatase Activity in Cerebral Ischemia

  Cui Zhou;Chong Li;Hong-Min Yu;Fa Zhang

  100
  Citations

• Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats.

  Unknown

  98
  Citations

• Extracellular signal-regulated kinase and c-Jun N-terminal protein kinase in ischemic tolerance.

  Zhenglin Gu;Qian Jiang;Guangyi Zhang

  95
  Citations

• The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region

  J. Pan;Q.-G. Zhang;G.-Y. Zhang

  93
  Citations

• Lithium reduced N-methyl-D-aspartate receptor subunit 2A tyrosine phosphorylation and its interactions with Src and Fyn mediated by PSD-95 in rat hippocampus following cerebral ischemia.

  Juan Ma;Guang-Yi Zhang

  92
  Citations

• Activation of NMDA receptors and L-type voltage-gated calcium channels mediates enhanced formation of Fyn-PSD95-NR2A complex after transient brain ischemia.

  Xiao-Yu Hou;Guang-Yi Zhang;Jing-Zhi Yan;Min Chen

  86
  Citations

• Neuroprotection of Tat-GluR6-9c against neuronal death induced by kainate in rat hippocampus via nuclear and non-nuclear pathways.

  Xiao-Mei Liu;Dong-Sheng Pei;Qiu-Hua Guan;Ya-Feng Sun

  85
  Citations

• Exogenous nitric oxide negatively regulates c-Jun N-terminal kinase activation via inhibiting endogenous NO-induced S-nitrosylation during cerebral ischemia and reperfusion in rat hippocampus.

  Dong-Sheng Pei;Yuan-Jian Song;Hong-Min Yu;Wei-Wei Hu

  85
  Citations

• c-Jun N-terminal kinase activation in hippocampal CA1 region was involved in ischemic injury.

  Zhenglin Gu;Qian Jiang;Guangyi Zhang

  83
  Citations

• Antioxidants attenuate reperfusion injury after global brain ischemia through inhibiting nuclear factor-kappa B activity in rats

  Wan-Hua Shen;Chun-Yi Zhang;Guang-Yi Zhang

  80
  Citations

• Diphosphorylation of extracellular signal-regulated kinases and c-Jun N-terminal protein kinases in brain ischemic tolerance in rat.

  Zhenglin Gu;Zhenglin Gu;Qian Jiang;Guangyi Zhang;Zhaochun Cui

  78
  Citations