World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
128
Citations
65032
World Ranking
2695
National Ranking
1505

Research.com Recognitions

  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2010 - Fellow of the American Statistical Association (ASA)

Overview

Yu Shyr is affiliated with Vanderbilt University Medical Center in the United States and has contributed extensively to research in medicine, particularly in oncology and molecular biology. Their research spans a wide range of topics, including cancer immunotherapy and biomarkers, COVID-19 and its healthcare impacts, and cancer genomics and diagnostics.

They have published significant work in leading journals, with frequent publications in:

  • Journal of Clinical Oncology
  • Journal of Thoracic Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • JAMA Oncology

Yu Shyr's most cited recent papers include:

  • "Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study" (2020, The Lancet)
  • "Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium" (2021, Annals of Oncology)
  • "Integrated Omics of Metastatic Colorectal Cancer" (2020, Cancer Cell)
  • "Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019" (2020, CHEST Journal)
  • "Biomarker Discovery and Validation: Statistical Considerations" (2021, Journal of Thoracic Oncology)

Their frequent coauthors include:

  • Chih-Yuan Hsu
  • Qi Liu
  • Rana R. McKay
  • Jeremy L. Warner
  • Patricia LoRusso

Yu Shyr's research areas encompass the following fields of study:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, their subfields of study include:

  • Oncology
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Infectious Diseases
  • Cancer Research

The main topics covered in their work are:

  • Cancer Immunotherapy and Biomarkers
  • COVID-19 and healthcare impacts
  • COVID-19 Clinical Research Studies
  • Cancer Genomics and Diagnostics
  • PARP inhibition in cancer therapy
  • Single-cell and spatial transcriptomics
  • Lung Cancer Treatments and Mutations

Yu Shyr has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2016 and as a Fellow of the American Statistical Association (ASA) since 2010.

Best Publications

  • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

    Brian D. Lehmann;Joshua A. Bauer;Xi Chen;Melinda E. Sanders

  • Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

    Jeffrey A. Sosman;Kevin B. Kim;Lynn Schuchter;Rene Gonzalez

  • Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.

    Nicole M. Kuderer;Toni K. Choueiri;Dimpy P. Shah;Yu Shyr

  • Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage.

    J D Morrow;B Frei;A W Longmire;J M Gaziano

  • Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

    Mark G. Kris;Bruce E. Johnson;Lynne D. Berry;David J. Kwiatkowski

  • Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

    Li Yang;Laura M. DeBusk;Koari Fukuda;Barbara Fingleton

  • Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection

    Brian D. Lehmann;Bojana Jovanović;Xi Chen;Monica V. Estrada

  • Reproducibility of the diagnosis of dysplasia in Barrett esophagus: A reaffirmation

    Elizabeth Montgomery;Mary P. Bronner;John R. Goldblum;Joel K. Greenson

  • Proteomic patterns of tumour subsets in non-small-cell lung cancer.

    Kiyoshi Yanagisawa;Yu Shyr;Baogang J Xu;Pierre P Massion

  • Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention.

    Howard Mertz;Victoria Morgan;Gordon Tanner;David Pickens

  • The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

    Anne E. Powell;Yang Wang;Yina Li;Emily J. Poulin

  • Nationwide Trends in Mastectomy for Early-Stage Breast Cancer

    Kristy L. Kummerow;Kristy L. Kummerow;Liping Du;David F. Penson;David F. Penson;Yu Shyr

  • Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer

    J. Joshua Smith;Natasha G. Deane;Fei Wu;Nipun B. Merchant

  • Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor–positive human breast cancer

    Todd W. Miller;Bryan T. Hennessy;Ana M. González-Angulo;Emily M. Fox

  • Plasma cytokine levels predict mortality in patients with acute renal failure.

    Edith M. Simmons;Jonathan Himmelfarb;M. Tugrul Sezer;Glenn M. Chertow

  • DC isoketal-modified proteins activate T cells and promote hypertension

    Annet Kirabo;Vanessa Fontana;Ana P C de Faria;Roxana Loperena

  • Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

    Douglas B. Johnson;Monica V. Estrada;Roberto Salgado;Violeta Sanchez

  • Reamed intramedullary nailing of the femur: 551 cases.

    Philip R. Wolinsky;Eric McCarty;Yu Shyr;Kenneth Johnson

  • Association of morbidity with markers of nutrition and inflammation in chronic hemodialysis patients: a prospective study.

    T. Alp Ikizler;Rebecca L. Wingard;Janice Harvell;Yu Shyr

  • Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta.

    R. Chinery;J. A. Brockman;M. O. Peeler;Yu Shyr

Frequent Co-Authors

Pierre P. Massion
Pierre P. Massion Vanderbilt University Medical Center
Jennifer A. Pietenpol
Jennifer A. Pietenpol Vanderbilt University Medical Center
David P. Carbone
David P. Carbone The Ohio State University
David H. Johnson
David H. Johnson The University of Texas Southwestern Medical Center
David C. Samuels
David C. Samuels Vanderbilt University
Wei Zheng
Wei Zheng Vanderbilt University Medical Center
Raymond M. Hakim
Raymond M. Hakim Vanderbilt University
T. Alp Ikizler
T. Alp Ikizler Vanderbilt University Medical Center
Leora Horn
Leora Horn Vanderbilt University Medical Center
Richard M. Caprioli
Richard M. Caprioli Vanderbilt University

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