2026 David C. Samuels: Genetics Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Genetics	59	3233	3059	1404	1318	194	13357

Overview

David C. Samuels is affiliated with Vanderbilt University in the United States. Their research spans Medicine and Biochemistry, Genetics, and Molecular Biology, with published work emphasizing molecular biology, epidemiology, virology, genetics, and emergency medicine. The focus areas of their research include HIV research and treatment, HIV-related health complications and treatments, opioid use disorder treatment, substance abuse treatment and outcomes, RNA regulation and disease, RNA and protein synthesis mechanisms, and CRISPR and genetic engineering.

Their recent publications include the following papers:

MitoTrace: A Computational Framework for Analyzing Mitochondrial Variation in Single-Cell RNA Sequencing Data, 2023, Genes
LYSMD3: A mammalian pattern recognition receptor for chitin, 2021, Cell Reports
Plasma Arginine and Citrulline are Elevated in Diabetic Retinopathy, 2021, American Journal of Ophthalmology
Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models, 2021, Journal of Clinical Investigation
EditPredict: Prediction of RNA editable sites with convolutional neural network, 2021, Genomics

They frequently publish in venues such as bioRxiv (Cold Spring Harbor Laboratory), Clinical Infectious Diseases, Journal of Biological Chemistry, Trends in Genetics, and Genes.

Frequent coauthors with whom David C. Samuels has collaborated include:

Todd Hulgan
Lori Schirle
Alvin D. Jeffery
Sandra Sanchez-Roige
Yan Guo

Their substantial work on HIV research and treatment reflects a multidisciplinary approach that integrates clinical infectious diseases, molecular biology, and genetic engineering methodologies. Their studies also address opioid use disorder and substance abuse treatment, which aligns with emerging concerns in public health and therapy optimization.

Overall, David C. Samuels's publication record demonstrates involvement in complex biological and medical research topics, with an emphasis on the molecular and genetic underpinnings of disease processes and therapeutic interventions.

Best Publications

Mitochondrial DNA mutations in human colonic crypt stem cells

Robert W. Taylor;Martin J. Barron;Gillian M. Borthwick;Amy Gospel

765
Citations
Pathogenic Mitochondrial DNA Mutations Are Common in the General Population

Hannah R. Elliott;David C. Samuels;James A. Eden;Caroline L. Relton

712
Citations
A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes

Lynsey M. Cree;David C. Samuels;Susana Chuva De Sousa Lopes;Harsha Karur Rajasimha

563
Citations
What causes mitochondrial DNA deletions in human cells

Kim J Krishnan;Amy K Reeve;David C Samuels;Patrick F Chinnery

524
Citations
Universal heteroplasmy of human mitochondrial DNA

Brendan A.I. Payne;Ian J. Wilson;Patrick Yu-Wai-Man;Jonathan Coxhead

417
Citations
Random Intracellular Drift Explains the Clonal Expansion of Mitochondrial DNA Mutations with Age

Joanna Elson;David Samuels;Doug Turnbull;Patrick Chinnery

386
Citations
The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both?

Patrick F Chinnery;David R Thorburn;David C Samuels;Sarah L White

313
Citations
Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?

Patrick F Chinnery;David C Samuels;Joanna Elson;Douglass M Turnbull

311
Citations
Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations

Brendan A I Payne;Brendan A I Payne;Ian J Wilson;Charlotte A Hateley;Rita Horvath

257
Citations
Relaxed Replication of mtDNA: A Model with Implications for the Expression of Disease

Patrick F. Chinnery;David C. Samuels

240
Citations
Large scale comparison of gene expression levels by microarrays and RNAseq using TCGA data.

Yan Guo;Quanhu Sheng;Jiang Li;Fei Ye

219
Citations
Two direct repeats cause most human mtDNA deletions

David C. Samuels;Eric A. Schon;Patrick F. Chinnery

216
Citations
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan

Dan-Qian Chen;Gang Cao;Hua Chen;Christos P. Argyopoulos

212
Citations
Epigenetics, epidemiology and mitochondrial DNA diseases

Patrick Francis Chinnery;Hannah R Elliott;Gavin Hudson;David C Samuels

210
Citations
Illumina human exome genotyping array clustering and quality control

Yan Guo;Jing He;Shilin Zhao;Hui Wu

200
Citations
Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans.

Bryan L. Gitschlag;Cait S. Kirby;David C. Samuels;Rama D. Gangula

199
Citations
Random Genetic Drift Determines the Level of Mutant mtDNA in Human Primary Oocytes

D.T. Brown;D.C. Samuels;E.M. Michael;D.M. Turnbull

196
Citations
Three-stage quality control strategies for DNA re-sequencing data

Yan Guo;Fei Ye;Quanghu Sheng;Travis Clark

178
Citations
Selection against Pathogenic mtDNA Mutations in a Stem Cell Population Leads to the Loss of the 3243A→G Mutation in Blood

Harsha Karur Rajasimha;Patrick F. Chinnery;David C. Samuels

174
Citations
Genome measures used for quality control are dependent on gene function and ancestry

Jing Wang;Leonid Raskin;David C. Samuels;Yu Shyr

167
Citations

Frequent Co-Authors

Patrick F. Chinnery University of Cambridge

Carlo F. Barenghi Newcastle University

Yu Shyr Vanderbilt University Medical Center

Ying-Yong Zhao Northwest University

Ronald J. Ellis University of California, San Diego

Luísa Pereira University of Porto

Scott Letendre University of California, San Diego

Donald Franklin University of California, San Diego

Robert W. Taylor Newcastle University

Douglass M. Turnbull Newcastle University

External Links

Personal website of David C. Samuels

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