World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
46
Citations
10469
World Ranking
4591
National Ranking
2070

Overview

Xiaoying Shen is affiliated with Duke University in the United States and specializes in research within the fields of Immunology and Microbiology as well as Medicine. Their work spans a range of subfields including Immunology, Infectious Diseases, Virology, Molecular Biology, and Radiology, Nuclear Medicine and Imaging. This interdisciplinary focus supports investigations into immune system mechanisms and infectious agents.

The scientist has contributed extensively to studies on HIV research and treatment, SARS-CoV-2 and COVID-19 research, immunotherapy and immune responses, immune cell function and interaction, T-cell and B-cell immunology, monoclonal and polyclonal antibodies research, and COVID-19 clinical research studies.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • npj Vaccines
  • Journal of Virology
  • Frontiers in Immunology

Co-authorship collaborations have been formed with several researchers, notably:

  • David C. Montefiori
  • Georgia D. Tomaras
  • Guido Ferrari
  • Celia C. LaBranche
  • Bette Korber

Key research publications include:

  • "SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines" (2021, Cell Host & Microbe)
  • "Adjuvanting a subunit COVID-19 vaccine to induce protective immunity" (2021, Nature)
  • "Neutralization of SARS-CoV-2 Variants B.1.429 and B.1.351" (2021, New England Journal of Medicine)
  • "Defining the risk of SARS-CoV-2 variants on immune protection" (2022, Nature)
  • "Towards a population-based threshold of protection for COVID-19 vaccines" (2021, Vaccine)

Best Publications

  • Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

    Barton F. Haynes;Peter B. Gilbert;M. Juliana McElrath;Susan Zolla-Pazner

  • Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG

    Georgia D. Tomaras;Guido Ferrari;Xiaoying Shen;S. Munir Alam

  • SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines.

    Xiaoying Shen;Haili Tang;Charlene McDanal;Kshitij Wagh

  • Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.

    Prabhu S. Arunachalam;Alexandra C. Walls;Nadia Golden;Caroline Atyeo

  • Towards a population-based threshold of protection for COVID-19 vaccines

    Unknown

  • Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial

    Raphael Gottardo;Robert T. Bailer;Bette T. Korber;S. Gnanakaran

  • The Thai Phase III HIV Type 1 Vaccine Trial (RV144) Regimen Induces Antibodies That Target Conserved Regions Within the V2 Loop of gp120

    Nicos Karasavvas;Erik Billings;Mangala Rao;Constance Williams

  • Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

    Hui Li;Shuyi Wang;Rui Kong;Wenge Ding

  • Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals

    Georgia D. Tomaras;James M. Binley;Elin S. Gray;Emma T. Crooks

  • Diversion of HIV-1 vaccine–induced immunity by gp41-microbiota cross-reactive antibodies

    Wilton B. Williams;Hua Xin Liao;M. Anthony Moody;Thomas B. Kepler

  • Adjuvant-dependent Innate and Adaptive Immune Signatures of Risk of SIVmac251 Acquisition

    Monica Vaccari;Shari N Gordon;Slim Fourati;Luca Schifanella;Luca Schifanella

  • Neutralization of SARS-CoV-2 Variants B.1.429 and B.1.351.

    Xiaoying Shen;Haili Tang;Rolando Pajon;Gale Smith

  • Booster of mRNA-1273 Strengthens SARS-CoV-2 Omicron Neutralization

    Unknown

  • Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial.

    Susan Zolla-Pazner;Susan Zolla-Pazner;Allan C. deCamp;Timothy Cardozo;Nicos Karasavvas

  • Potent Immune Responses in Rhesus Macaques Induced by Nonviral Delivery of a Self-amplifying RNA Vaccine Expressing HIV Type 1 Envelope With a Cationic Nanoemulsion

    Willy M. Bogers;Herman Oostermeijer;Petra Mooij;Gerrit Koopman

  • Mapping SARS-CoV-2 antigenic relationships and serological responses

    Unknown

  • Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

    Sampa Santra;Georgia D. Tomaras;Ranjit Warrier;Nathan I. Nicely

  • Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

    Todd Bradley;Justin Pollara;Sampa Santra;Nathan Vandergrift

  • Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies

    Zhongyu Zhu;Haiyan Rebekah Qin;Weizao Chen;Qi Zhao

  • In Vivo gp41 Antibodies Targeting the 2F5 Monoclonal Antibody Epitope Mediate Human Immunodeficiency Virus Type 1 Neutralization Breadth

    Xiaoying Shen;Robert J. Parks;David C. Montefiori;Jennifer L. Kirchherr

  • HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies

    Genevieve G. Fouda;Nicole L. Yates;Justin Pollara;Xiaoying Shen

  • Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk

    Scott D. Neidich;Youyi Fong;Youyi Fong;Shuying S. Li;Daniel E. Geraghty

  • SARS-CoV-2 Variant B.1.1.7 is Susceptible to Neutralizing Antibodies Elicited by Ancestral Spike Vaccines

    Xiaoying Shen;Haili Tang;Charlene McDanal;Kshitij Wagh

Frequent Co-Authors

Georgia D. Tomaras
Georgia D. Tomaras Duke University
David C. Montefiori
David C. Montefiori Duke University
Guido Ferrari
Guido Ferrari Duke University
Barton F. Haynes
Barton F. Haynes Duke University
Celia C. LaBranche
Celia C. LaBranche Duke University
Kevin O. Saunders
Kevin O. Saunders Duke University
Sampa Santra
Sampa Santra Beth Israel Deaconess Medical Center
Peter B. Gilbert
Peter B. Gilbert Fred Hutchinson Cancer Research Center
David Venzon
David Venzon National Institutes of Health
Sallie R. Permar
Sallie R. Permar Duke University

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