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William H. Konigsberg

William H. Konigsberg

D-Index & Metrics

Chemistry

D-Index
66
Citations
15270
World Ranking
7293
National Ranking
2161

Molecular Biology

D-Index
69
Citations
15786
World Ranking
1480
National Ranking
751

Overview

William H. Konigsberg is affiliated with Yale University in the United States. Their research primarily focuses on medical and biochemical fields, with an emphasis on molecular biology and infectious diseases.

The scientist's recent publications cover a range of topics, including viral mechanisms, enzymatic activity, and natural compounds. Notable papers include:

  • Bioactivity and mechanisms of flavonoids in decreasing insulin resistance, 2023, Journal of Enzyme Inhibition and Medicinal Chemistry
  • Two-Metal-Ion Catalysis: Inhibition of DNA Polymerase Activity by a Third Divalent Metal Ion, 2022, Frontiers in Molecular Biosciences
  • Structural Insights into Binding of Remdesivir Triphosphate within the Replication-Transcription Complex of SARS-CoV-2, 2022, Biochemistry
  • Insights into Binding of Single-Stranded Viral RNA Template to the Replication-Transcription Complex of SARS-CoV-2 for the Priming Reaction from Molecular Dynamics Simulations, 2022, Biochemistry
  • Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1, 2022, Biochemistry

The main fields of study reflected in this work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, subfields of particular focus are:

  • Molecular Biology
  • Infectious Diseases
  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Oncology

Their research topics cover a range of areas, clearly linking biological and chemical aspects of disease and treatment:

  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • Natural Antidiabetic Agents Studies
  • Phytochemicals and Antioxidant Activities
  • Bioactive natural compounds
  • Metal complexes synthesis and properties
  • DNA and Nucleic Acid Chemistry

Frequent coauthors collaborating with William H. Konigsberg include:

  • Jimin Wang
  • Yuanjun Shi
  • Krystle Reiss
  • Federica Maschietto
  • Elias Lolis

The scientist has published primarily in journals such as:

  • Biochemistry
  • Journal of Enzyme Inhibition and Medicinal Chemistry
  • Frontiers in Molecular Biosciences

Best Publications

  • The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.

    David W. Banner;Allan D'Arcy;Christiana Chène;Fritz K. Winkler

  • Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69

    J. Wang;A.K.M.A. Sattar;C.C. Wang;J.D. Karam

  • Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation.

    Michael E. Bromberg;William H. Konigsberg;Jennifer F. Madison;Aruna Pawashe

  • Sequences of the recA gene and protein

    A Sancar;C Stachelek;W Konigsberg;W D Rupp

  • Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA.

    Eleanor K. Spicer;Renata Horton;Laura Bloem;Ronald Bach

  • Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase.

    Arthur L. Horwich;Wayne A. Fenton;Kenneth R. Williams;Frantisek Kalousek

  • Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA

    Yousif Shamoo;Alan M. Friedman;Mark R. Parsons;William H. Konigsberg

  • A micromethod for complete removal of dodecyl sulfate from proteins by ion-pair extraction.

    L.E. Henderson;S. Oroszlan;W. Konigsberg

  • [13] Reduction of disulfide bonds in proteins with dithiothreitol

    William Konigsberg

  • High-frequency generalised transduction by bacteriophage T4.

    Geoffrey G. Wilson;Karen K. Y. Young;Gordon J. Edlin;William Konigsberg

  • Nucleic acid polymerases use a general acid for nucleotidyl transfer.

    Christian Castro;Eric D. Smidansky;Jamie J. Arnold;Kenneth R. Maksimchuk

  • On the specificity of antibodies

    Frank F. Richards;W. H. Konigsberg;R. W. Rosenstein;Janos M. Varga

  • Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases

    Christian Castro;Eric Smidansky;Kenneth R. Maksimchuk;Jamie J. Arnold

  • The covalent structure of a human gamma G-immunoglobulin. II. Isolation and characterization of the cyanogen bromide fragments.

    Myron J. Waxdal;William H. Konigsberg;Walter L. Henley;Gerald M. Edelman

  • Tumor necrosis factor enhances expression of tissue factor mRNA in endothelial cells.

    Edward M. Conway;Ronald R Bach;Robert D. Rosenberg;William H. Konigsberg

  • Gene 32 protein, the single-stranded DNA binding protein from bacteriophage T4, is a zinc metalloprotein.

    David P. Giedroc;Kathleen M. Keating;Kenneth R. Williams;William H. Konigsberg

  • Removal of sodium dodecyl sulfate from proteins by ion-pair extraction.

    William H. Konigsberg;Lou Henderson

  • Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule.

    Michael E. Bromberg;Ranjini Sundaram;Robert J. Homer;Alan Garen

  • Purification and characterization of bovine tissue factor.

    Unknown

  • Reinvestigation of a region of the fd bacteriophage coat protein sequence.

    Y. Nakashima;W. Konigsberg

  • Evidence for use of rare codons in the dnaG gene and other regulatory genes of Escherichia coli.

    Unknown

  • Single-molecule and ensemble fluorescence assays for a functionally important conformational change in T7 DNA polymerase

    Guobin Luo;Mina Wang;William H. Konigsberg;X. Sunney Xie

Frequent Co-Authors

Kenneth R. Williams
Kenneth R. Williams Yale University
Jimin Wang
Jimin Wang Yale University
Gerald M. Edelman
Gerald M. Edelman Neurosciences Institute
Bruce A. Cunningham
Bruce A. Cunningham Scripps Research Institute
Thomas A. Steitz
Thomas A. Steitz Yale University
Peter J. Hotez
Peter J. Hotez Baylor College of Medicine
Robert K. Yu
Robert K. Yu Augusta University
Peter Lengyel
Peter Lengyel Yale University
Dieter Söll
Dieter Söll Yale University

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