World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
45
Citations
6452
World Ranking
16566
National Ranking
4115

Overview

Tina L. Amyes is affiliated with the University at Buffalo, State University of New York in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, along with contributions to medicine. Publications reflect engagement with molecular biology and physiology as well as surgical and materials chemistry subfields.

The scientist's recent work includes key topics such as:

  • Erythrocyte Function and Pathophysiology
  • Metabolism, Diabetes, and Cancer
  • Pancreatic function and diabetes
  • Biochemical and Molecular Research
  • Protein Structure and Dynamics
  • Enzyme Structure and Function

Amyes has contributed to peer-reviewed journals, including the following frequent publication venues:

  • Journal of the American Chemical Society
  • Accounts of Chemical Research

Notable recent papers authored or coauthored by Amyes include:

  • Phosphodianion Activation of Enzymes for Catalysis of Central Metabolic Reactions, 2021, Journal of the American Chemical Society
  • Linear Free Energy Relationships for Enzymatic Reactions: Fresh Insight from a Venerable Probe, 2021, Accounts of Chemical Research

The scientist frequently collaborates with colleagues such as Judith R. Cristobal, John P. Richard, Patrick Fernandez, and Richard W. Nagorski. These collaborations contribute to a cross-disciplinary approach, weaving insights from molecular and biochemical perspectives.

Best Publications

  • Formation and Stability of N-Heterocyclic Carbenes in Water: The Carbon Acid pKa of Imidazolium Cations in Aqueous Solution

    Tina L Amyes;Steven T Diver;John P Richard;Felix M Rivas

  • Lifetimes of oxocarbenium ions in aqueous solution from common ion inhibition of the solvolysis of α-azido ethers by added azide ion

    Tina L. Amyes;William P. Jencks

  • A role for flexible loops in enzyme catalysis.

    M Merced Malabanan;Tina L Amyes;John P Richard

  • Formation and stability of carbocations and carbanions in water and intrinsic barriers to their reactions.

    John P. Richard;Tina L. Amyes;Maria M. Toteva

  • Generation and stability of a simple thiol ester enolate in aqueous solution

    Tina L. Amyes;John P. Richard

  • Formation and Stability of Enolates of Acetamide and Acetate Anion: An Eigen Plot for Proton Transfer at α-Carbonyl Carbon

    John P. Richard;Glenn Williams;and AnnMarie C. O'Donoghue;Tina L. Amyes

  • Activation of orotidine 5'-monophosphate decarboxylase by phosphite dianion: the whole substrate is the sum of two parts.

    Tina L. Amyes;John P. Richard;James J. Tait

  • Specificity in transition state binding: the Pauling model revisited.

    Tina L. Amyes;John P. Richard

  • Enzymatic catalysis of proton transfer at carbon: activation of triosephosphate isomerase by phosphite dianion.

    Tina L. Amyes;John P. Richard

  • Phosphate Binding Energy and Catalysis by Small and Large Molecules

    Janet R. Morrow;Tina L. Amyes;John P. Richard

  • Proton transfer at carbon

    John P Richard;Tina L Amyes

  • Enzyme architecture: on the importance of being in a protein cage.

    John P Richard;Tina L Amyes;Bogdana Goryanova;Xiang Zhai

  • On the importance of being zwitterionic: enzymatic catalysis of decarboxylation and deprotonation of cationic carbon.

    John P. Richard;Tina L. Amyes

  • Formation and stability of a vinyl carbanion at the active site of orotidine 5'-monophosphate decarboxylase: pKa of the C-6 proton of enzyme-bound UMP.

    Tina L. Amyes;Bryant M. Wood;Kui Chan;John Alan Gerlt

  • Effect of .beta.-fluorine substituents on the rate and equilibrium constants for the reactions of .alpha.-substituted 4-methoxybenzyl carbocations and on the reactivity of a simple quinone methide

    John P. Richard;Tina L. Amyes;Li Bei;Vernon Stubblefield

  • Experiments and calculations for determination of the stabilities of benzyl, benzhydryl, and fluorenyl carbocations: antiaromaticity revisited

    Tina L. Amyes;John P. Richard;Michael Novak

  • Contribution of phosphate intrinsic binding energy to the enzymatic rate acceleration for triosephosphate isomerase.

    Tina L. Amyes;AnnMarie C. O'Donoghue;John P. Richard

  • A Substrate in Pieces: Allosteric Activation of Glycerol 3-Phosphate Dehydrogenase (NAD+) by Phosphite Dianion

    Wing-Yin Tsang;Tina L. Amyes;John P. Richard

  • Concurrent stepwise and concerted substitution reactions of 4-methoxybenzyl derivatives and the lifetime of the 4-methoxybenzyl carbocation.

    Tina L. Amyes;John P. Richard

  • Concerted bimolecular substitution reactions of acetal derivatives of propionaldehyde and benzaldehyde

    Tina L. Amyes;William P. Jencks

Frequent Co-Authors

John P. Richard
John P. Richard University at Buffalo, State University of New York
John A. Gerlt
John A. Gerlt University of Illinois at Urbana-Champaign
William P. Jencks
William P. Jencks Brandeis University
Birgit Strodel
Birgit Strodel Forschungszentrum Jülich
Steen Steenken
Steen Steenken Max Planck Society
Steven C. Almo
Steven C. Almo Albert Einstein College of Medicine
Janet R. Morrow
Janet R. Morrow University at Buffalo, State University of New York
Anthony J. Kirby
Anthony J. Kirby University of Cambridge
Rik K. Wierenga
Rik K. Wierenga University of Oulu
Andrew D. Mesecar
Andrew D. Mesecar Purdue University West Lafayette

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Chemistry opens doors to various online educational options and career pathways. Understanding the cost of these programs is essential for planning your education budget effectively. Similar to other fields, the cost of criminal justice degree programs can vary widely, offering a helpful comparison when considering tuition fees for online Chemistry degrees.

Many students opt for accredited programs to ensure quality and recognition. Just as choosing an accredited online criminal justice associate degree is important, selecting a properly accredited Chemistry program can improve job prospects and transfer opportunities.

Career paths related to Chemistry include roles similar to those in legal and healthcare sectors, where understanding salaries and job outlooks is crucial. For example, consulting paralegal salaries, provided in paralegal salary insights, can guide expectations regarding earning potential after obtaining a degree.

Additionally, becoming a pharmaceutical sales representative is a popular route for Chemistry graduates. Knowing how much do drug reps make can help students weigh the financial benefits of this career path alongside traditional scientific roles.

Best Scientists Citing Tina L. Amyes

Trending Scientists