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Microbiology

D-Index
58
Citations
10820
World Ranking
3460
National Ranking
305

Overview

Donna M. MacCallum is affiliated with the University of Aberdeen in the United Kingdom. Their research primarily focuses on medical and biological sciences, with a main emphasis on medicine. Subfields of their work include epidemiology, infectious diseases, dermatology, immunology and allergy, and molecular biology.

The scientist's research topics cover an array of areas, notably antifungal resistance and susceptibility, fungal infections and studies, nail diseases and treatments, dermatology and skin diseases, allergic rhinitis and sensitization, peptidase inhibition and analysis, and antimicrobial resistance in Staphylococcus.

Donna M. MacCallum has contributed to several academic publications. Recent papers include:

  • General hospital outbreak of invasive candidiasis due to azole-resistant Candida parapsilosis associated with an Erg11 Y132F mutation, 2020, Medical Mycology
  • Three Related Enzymes in Candida albicans Achieve Arginine- and Agmatine-Dependent Metabolism That Is Essential for Growth and Fungal Virulence, 2020, mBio
  • Host Responses in an Ex Vivo Human Skin Model Challenged With Malassezia sympodialis, 2021, Frontiers in Cellular and Infection Microbiology
  • Monoclonal Antibodies Targeting Surface-Exposed Epitopes of Candida albicans Cell Wall Proteins Confer In Vivo Protection in an Infection Model, 2022, Antimicrobial Agents and Chemotherapy
  • Blocking Polyphosphate Mobilization Inhibits Pho4 Activation and Virulence in the Pathogen Candida albicans, 2022, mBio

Frequent co-authors collaborating with Donna M. MacCallum include Carol A. Munro, Dora Corzo-León, Soumya Palliyil, Mark Mawer, and Sami A. Alawfi.

The scientist publishes regularly in several venues, with multiple works appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • Methods in molecular biology
  • Medical Mycology
  • Frontiers in Cellular and Infection Microbiology

Best Publications

  • Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors

    Mihai G. Netea;Neil A.R. Gow;Carol A. Munro;Steven Bates

  • Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood.

    Chantal Fradin;Piet De Groot;Donna Margaret MacCallum;Martin Schaller

  • NRG1 represses yeast–hypha morphogenesis and hypha‐specific gene expression in Candida albicans

    A.Munir A. Murad;Ping Leng;Melissa Straffon;Jill Wishart

  • Niche-specific regulation of central metabolic pathways in a fungal pathogen

    Caroline Barelle;Claire L Priest;Donna Margaret MacCallum;Neil Andrew Robert Gow

  • Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions.

    Antje Albrecht;Angelika Felk;Angelika Felk;Iva Pichova;Julian R Naglik

  • Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen.

    Iuliana Veronica Ene;Ashok Adya;Silvia Wehmeier;Alex Brand

  • Ectopic Expression of URA3 Can Influence the Virulence Phenotypes and Proteome of Candida albicans but Can Be Overcome by Targeted Reintegration of URA3 at the RPS10 Locus

    Alexandra Carolyn Brand;Donna Margaret MacCallum;Alistair James Petersen Brown;Neil Andrew Robert Gow

  • Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

    Jeanette Wagener;R. K.Subbarao Malireddi;Megan D. Lenardon;Martin Köberle

  • Outer Chain N-Glycans Are Required for Cell Wall Integrity and Virulence of Candida albicans

    Steven Bates;H. Bleddyn Hughes;Carol A. Munro;William P.H. Thomas

  • Elevated Cell Wall Chitin in Candida albicans Confers Echinocandin Resistance In Vivo

    Keunsook K. Lee;Donna M. MacCallum;Mette D. Jacobsen;Louise A. Walker

  • Lactate signalling regulates fungal β-glucan masking and immune evasion.

    Elizabeth R Ballou;Gabriela M Avelar;Delma S Childers;Joanna Mackie

  • Mnt1p and Mnt2p of Candida albicans Are Partially Redundant α-1,2-Mannosyltransferases That Participate in O-Linked Mannosylation and Are Required for Adhesion and Virulence

    Carol A. Munro;Steven Bates;Ed T. Buurman;H. Bleddyn Hughes

  • Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1

    Mohlopheni J. Marakalala;Simon Vautier;Joanna Potrykus;Louise A. Walker

  • Candida albicans Pmr1p, a secretory pathway P-type Ca2+/Mn2+-ATPase, is required for glycosylation and virulence.

    Steven Bates;Donna M. MacCallum;Gwyneth Bertram;Carol A. Munro

  • Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition

    Sarah L. Sherrington;Eleanor Sorsby;Nabeel Mahtey;Pizga Kumwenda

  • The Candida albicans CaACE2 gene affects morphogenesis, adherence and virulence

    Mary T. Kelly;Donna M. MacCallum;Susanne D. Clancy;Frank C. Odds

  • Property Differences among the Four Major Candida albicans Strain Clades

    Donna M. MacCallum;Luis Castillo;Kerstin Nather;Carol A. Munro

  • The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

    Ivy M. Dambuza;Thomas Drake;Ambre Chapuis;Xin Zhou

  • Temporal events in the intravenous challenge model for experimental Candida albicans infections in female mice.

    Donna Margaret MacCallum;Frank Christopher Odds

  • Thioredoxin Regulates Multiple Hydrogen Peroxide-Induced Signaling Pathways in Candida albicans

    Alessandra da Silva Dantas;Miranda J. Patterson;Deborah A. Smith;Donna M. MacCallum

  • Loss of Cell Wall Mannosylphosphate in Candida albicans Does Not Influence Macrophage Recognition

    Richard P. Hobson;Carol A. Munro;Steven Bates;Donna M. MacCallum

  • Niche-Specific Activation of the Oxidative Stress Response by the Pathogenic Fungus Candida albicans

    Brice Patrick Enjalbert;Donna Margaret MacCallum;Frank Christopher Odds;Alistair James Petersen Brown

Frequent Co-Authors

Neil A. R. Gow
Neil A. R. Gow University of Exeter
Alistair J. P. Brown
Alistair J. P. Brown University of Exeter
Frank C. Odds
Frank C. Odds University of Aberdeen
Carol A. Munro
Carol A. Munro University of Aberdeen
Gordon D. Brown
Gordon D. Brown University of Exeter
Mihai G. Netea
Mihai G. Netea Radboud University
Graeme I. Murray
Graeme I. Murray University of Aberdeen
Bernhard Hube
Bernhard Hube Leibniz Association
Martin Schaller
Martin Schaller University of Tübingen
Derek J. Sullivan
Derek J. Sullivan Trinity College Dublin

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