World's Best Scientists 2026 revealed!
John C. Vederas

John C. Vederas

Award Badge
Chemistry
Canada
2025
Award Badge
Biology and Biochemistry
Canada
2023

D-Index & Metrics

Chemistry

D-Index
85
Citations
28121
World Ranking
2649
National Ranking
56

Biology and Biochemistry

D-Index
86
Citations
28762
World Ranking
2944
National Ranking
91

Research.com Recognitions

  • 2025 - Research.com Chemistry in Canada Leader Award
  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2022 - Research.com Chemistry in Canada Leader Award
  • 2009 - Fellow of the Royal Society, United Kingdom
  • 2008 - Chemical Institute of Canada Medal
  • 1997 - Fellow of the Royal Society of Canada Academy of Science

Overview

John C. Vederas is affiliated with the University of Alberta in Canada and contributes extensively to research in Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Infectious Diseases, Pharmacology, Ecology, and Organic Chemistry.

The scientist's main research topics include SARS-CoV-2 and COVID-19 Research, Computational Drug Discovery Methods, Animal Virus Infections Studies, Probiotics and Fermented Foods, Forest Insect Ecology and Management, Entomopathogenic Microorganisms in Pest Control, and Apelin-related biomedical research.

Among recent publications by John C. Vederas are:

  • Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication, 2020, Nature Communications
  • Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability, 2021, Journal of Medicinal Chemistry
  • Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome, 2021, Cell Reports
  • Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies, 2021, European Journal of Medicinal Chemistry
  • Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with John C. Vederas include Tess Lamer, Marco J. van Belkum, M. Joanne Lemieux, Conrad Fischer, and Elena Arutyunova.

Their research outputs are commonly published in venues such as Nature Communications, RSC Medicinal Chemistry, bioRxiv (Cold Spring Harbor Laboratory), Organic Letters, and Journal of Medicinal Chemistry.

Throughout their career, John C. Vederas has been recognized with several awards, including being named a Fellow of the Royal Society, United Kingdom, in 2009, receiving the Chemical Institute of Canada Medal in 2008, and being elected a Fellow of the Royal Society of Canada in 1997 under the Academy of Science.

Best Publications

  • Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

    Jesse W.-H. Li;John C. Vederas

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

    Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers

  • Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis

    Jonathan Kennedy;Karine Auclair;Steven G. Kendrew;Cheonseok Park

  • Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile

    Mary C. Rea;Clarissa S. Sit;Evelyn Clayton;Paula M. O'Connor

  • Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication.

    Wayne Vuong;Muhammad Bashir Khan;Conrad Fischer;Elena Arutyunova

  • Characterization of leucocin A-UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum.

    J W Hastings;M Sailer;K Johnson;K L Roy

  • Lipopeptides from Bacillus and Paenibacillus spp.: A Gold Mine of Antibiotic Candidates

    Stephen A Cochrane;John C Vederas

  • Complete reconstitution of a highly reducing iterative polyketide synthase.

    Suzanne M. Ma;Jesse W.-H. Li;Jin W. Choi;Hui Zhou

  • Two-peptide bacteriocins produced by lactic acid bacteria.

    Sylvie Garneau;Nathaniel I Martin;John C Vederas

  • Lovastatin Nonaketide Synthase Catalyzes an Intramolecular Diels−Alder Reaction of a Substrate Analogue

    Karine Auclair;Andrew Sutherland;Jonathan Kennedy;David J. Witter

  • Chemical and genetic characterization of bacteriocins produced by Carnobacterium piscicola LV17B.

    L. E. N. Quadri;M. Sailer;K. L. Roy;J. C. Vederas

  • Amination of chiral enolates by dialkyl azodiformates. Synthesis of .alpha.-hydrazino acids and .alpha.-amino acids

    Laird A. Trimble;John C. Vederas

  • Structure of Subtilosin A, a Cyclic Antimicrobial Peptide from Bacillus subtilis with Unusual Sulfur to α-Carbon Cross-Links: Formation and Reduction of α-Thio-α-Amino Acid Derivatives†,‡

    Karen E. Kawulka;Tara Sprules;Christopher M. Diaper;Randy M. Whittal

  • Conversion of serine to stereochemically pure .beta.-substituted .alpha.-amino acids via .beta.-lactones

    Lee D. Arnold;Thomas H. Kalantar;John C. Vederas

  • Loss of Apelin Exacerbates Myocardial Infarction Adverse Remodeling and Ischemia-Reperfusion Injury: Therapeutic Potential of Synthetic Apelin Analogues

    Wang Wang;Shaun M.K. McKinnie;Vaibhav B. Patel;George Haddad

  • Genes of the sbo-alb Locus of Bacillus subtilis Are Required for Production of the Antilisterial Bacteriocin Subtilosin

    Guolu Zheng;Liang Z. Yan;John C. Vederas;Peter Zuber

  • Three-dimensional structure of leucocin A in trifluoroethanol and dodecylphosphocholine micelles: spatial location of residues critical for biological activity in type IIa bacteriocins from lactic acid bacteria.

    Fregeau Gallagher Nl;Sailer M;Niemczura Wp;Nakashima Tt

  • Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

    Martin Ni;Sprules T;Carpenter Mr;Cotter Pd

  • Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System.

    Wang Wang;Shaun M.K. McKinnie;Maikel Farhan;Manish Paul

  • Isolation and Characterization of Carnocyclin A, a Novel Circular Bacteriocin Produced by Carnobacterium maltaromaticum UAL307

    Leah A. Martin-Visscher;Marco J. van Belkum;Sylvie Garneau-Tsodikova;Randy M. Whittal

  • A signal peptide secretion-dependent bacteriocin from Carnobacterium divergens.

    R W Worobo;M J Van Belkum;M Sailer;K L Roy

  • [Drug discovery and natural products: end of era or an endless frontier?].

    Jesse W H Li;J C Vederas

Frequent Co-Authors

Michael N. G. James
Michael N. G. James University of Alberta
Michael E. Stiles
Michael E. Stiles CanBiocin (Canada)
Yi Tang
Yi Tang University of California, Los Angeles
Thomas J. Simpson
Thomas J. Simpson University of Bristol
John S. Blanchard
John S. Blanchard Albert Einstein College of Medicine
Gavin Y. Oudit
Gavin Y. Oudit University of Alberta
David S. Wishart
David S. Wishart University of Alberta
Monica M. Palcic
Monica M. Palcic Carlsberg Laboratory
Heinz G. Floss
Heinz G. Floss University of Washington
C. Richard Hutchinson
C. Richard Hutchinson Bristol-Myers Squibb (Canada)

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Chemistry opens doors to various career paths, many of which can be further explored through online programs. For example, some students may choose to complement their Chemistry studies with an associate’s degree, which can lead to specialized roles. Understanding the paralegal salary associate's degree landscape offers insight into how degree choices influence earnings and opportunities, even outside of traditional chemistry roles.

For those interested in the pharmaceutical industry, a background in Chemistry is invaluable. Careers such as pharmaceutical sales representatives benefit from a strong grasp of chemical compounds and drug interactions. Explore the typical pharmaceutical rep salary and career paths to understand potential growth and income in this field.

Becoming a licensed pharmacist is another rewarding avenue for Chemistry graduates. The profession requires specific training and certification, often starting with key steps to become a pharmacist. This pathway combines Chemistry knowledge with clinical practice, offering a stable and well-compensated career.

Additionally, those fascinated by forensic and medical applications of Chemistry might consider roles such as autopsy technicians. These professionals apply scientific methods to assist in medical examinations and investigations. Learn more about the education requirements, salary expectations, and career outlook for an autopsy technician to see if this path aligns with your interests.

Best Scientists Citing John C. Vederas

Trending Scientists

Recently Published Articles