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Immunology

D-Index
49
Citations
7667
World Ranking
4361
National Ranking
16

Overview

Seung-Ki Kwok is affiliated with Seoul St. Mary's Hospital in South Korea and has an extensive research portfolio primarily within medicine and immunology and microbiology. Their work spans several subfields, including rheumatology, immunology, physiology, molecular biology, and surgery.

The scientist's research topics focus notably on salivary gland disorders and functions, systemic lupus erythematosus, rheumatoid arthritis research and therapies, salivary gland tumors diagnosis and treatment, spondyloarthritis studies and treatments, T-cell and B-cell immunology, and inflammasome and immune disorders.

Recent publications include:

  • Short-chain fatty acid butyrate induces IL-10-producing B cells by regulating circadian-clock-related genes to ameliorate Sjögren's syndrome (2021, Journal of Autoimmunity)
  • Lactobacillus acidophilus Supplementation Exerts a Synergistic Effect on Tacrolimus Efficacy by Modulating Th17/Treg Balance in Lupus-Prone Mice via the SIGNR3 Pathway (2021, Frontiers in Immunology)
  • Type I Interferon Increases Inflammasomes Associated Pyroptosis in the Salivary Glands of Patients with Primary Sjögren's Syndrome (2020, Immune Network)
  • 1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis (2020, Journal of Korean Medical Science)
  • Baricitinib Attenuates Autoimmune Phenotype and Podocyte Injury in a Murine Model of Systemic Lupus Erythematosus (2021, Frontiers in Immunology)

Seung-Ki Kwok has frequently published in venues such as:

  • Annals of the Rheumatic Diseases
  • The Korean Journal of Internal Medicine
  • Frontiers in Immunology
  • Journal of Translational Medicine
  • Clinical and Experimental Rheumatology

Collaborative work includes frequent co-authorship with researchers such as Sung-Hwan Park, Jennifer Lee, Youngjae Park, Mi-La Cho, and Ji Hyeon Ju.

Best Publications

  • Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium.

    Pilar Brito-Zerón;Pilar Brito-Zerón;Nihan Acar-Denizli;Margit Zeher;Astrid Rasmussen

  • IL-17-mediated mitochondrial dysfunction impairs apoptosis in rheumatoid arthritis synovial fibroblasts through activation of autophagy.

    Eun Kyung Kim;Jeong-Eun Kwon;Seon-Young Lee;Eun-Jung Lee

  • Lupus mesenteric vasculitis can cause acute abdominal pain in patients with SLE.

    Ji Hyeon Ju;Jun-Ki Min;Chan-Kwon Jung;Soon Nam Oh

  • IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients

    Yu-Jung Heo;Young-Bin Joo;Hye-Jwa Oh;Mi-Kyung Park

  • TLR2 ligation induces the production of IL-23/IL- 17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome

    Seung-Ki Kwok;Mi-La Cho;Yang-Mi Her;Hye-Joa Oh

  • Proinflammatory Role of Vascular Endothelial Growth Factor in the Pathogenesis of Rheumatoid Arthritis: Prospects for Therapeutic Intervention

    Seung-Ah Yoo;Seung-Ki Kwok;Wan-Uk Kim

  • Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice.

    Min-Jung Park;Sung-Hee Lee;Eun-Kyung Kim;Eun-Jung Lee

  • STA‐21, a Promising STAT‐3 Inhibitor That Reciprocally Regulates Th17 and Treg Cells, Inhibits Osteoclastogenesis in Mice and Humans and Alleviates Autoimmune Inflammation in an Experimental Model of Rheumatoid Arthritis

    Jin-Sil Park;Seung-Ki Kwok;Mi-Ae Lim;Eun-Kyung Kim

  • Retinoic Acid Attenuates Rheumatoid Inflammation in Mice

    Seung-Ki Kwok;Mi-Kyung Park;Mi-La Cho;Hye-Jwa Oh

  • Interleukin-21 promotes osteoclastogenesis in humans with rheumatoid arthritis and in mice with collagen-induced arthritis

    Seung-Ki Kwok;Mi-La Cho;Mi-Kyung Park;Hye-Joa Oh

  • How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project).

    Pilar Brito-Zerón;Nihan Acar-Denizli;Wan-Fai Ng;Margit Zeher

  • Impact of interleukin-21 in the pathogenesis of primary Sjogren's syndrome: increased serum levels of interleukin-21 and its expression in the labial salivary glands

    Kwi Young Kang;Hyun Ok Kim;Seung-Ki Kwok;Ji Hyeon Ju

  • TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome.

    Seung-Ki Kwok;Mi-La Cho;Yang-Mi Her;Hye-Joa Oh

  • IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation

    Seon-Yeong Lee;Seung-Ki Kwok;Hye-Jin Son;Jun-Geol Ryu

  • JAK2-STAT3 Blockade by AG490 Suppresses Autoimmune Arthritis in Mice via Reciprocal Regulation of Regulatory T Cells and Th17 Cells

    Jin-Sil Park;Jennifer Lee;Mi-Ae Lim;Eun-Kyung Kim

  • Myeloid-Derived Suppressor Cells Induce the Expansion of Regulatory B Cells and Ameliorate Autoimmunity in the Sanroque Mouse Model of Systemic Lupus Erythematosus

    Min-Jung Park;Sung-Hee Lee;Eun-Kyung Kim;Eun-Jung Lee

  • CTLA4-Ig modifies dendritic cells from mice with collagen-induced arthritis to increase the CD4+CD25+Foxp3+ regulatory T cell population

    Hyeok-Jae Ko;Mi-La Cho;Seon-Yeong Lee;Hye-Jwa Oh

  • Adipose Tissue-Derived Mesenchymal Stem Cells Induce Expansion of Interleukin-10-Producing Regulatory B Cells and Ameliorate Autoimmunity in a Murine Model of Systemic Lupus Erythematosus:

    Min-Jung Park;Seung-Ki Kwok;Sung-Hee Lee;Eun-Kyung Kim

  • Type II collagen oral tolerance; mechanism and role in collagen-induced arthritis and rheumatoid arthritis

    Kyung-Su Park;Min-Jung Park;Mi-La Cho;Seung-Ki Kwok

  • Lupus enteritis: clinical characteristics, risk factor for relapse and association with anti-endothelial cell antibody.

    S.-K. Kwok;S.-H. Seo;J.H. Ju;K.-S. Park

  • Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells.

    Ji Hyeon Ju;Yu-Jung Heo;Mi-La Cho;Joo-Yeon Jhun

  • Increased Levels of Interleukin 34 in Serum and Synovial Fluid Are Associated with Rheumatoid Factor and Anticyclic Citrullinated Peptide Antibody Titers in Patients with Rheumatoid Arthritis

    Su-Jin Moon;Yeon-Sik Hong;Ji Hyeon Ju;Seung-Ki Kwok

Frequent Co-Authors

Sung-Hwan Park
Sung-Hwan Park Catholic University of Korea
Mi-La Cho
Mi-La Cho Catholic University of Korea
Ho-Youn Kim
Ho-Youn Kim Catholic University of Korea
Wan-Uk Kim
Wan-Uk Kim Catholic University of Korea
Roberto Giacomelli
Roberto Giacomelli Campus Bio Medico University Hospital
Manuel Ramos-Casals
Manuel Ramos-Casals Hospital Clinic of Barcelona
Damien Sene
Damien Sene Université Paris Cité
Hendrika Bootsma
Hendrika Bootsma University Medical Center Groningen
David A. Isenberg
David A. Isenberg University College London
Fabiola Atzeni
Fabiola Atzeni University of Messina

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