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Biology and Biochemistry

D-Index
56
Citations
18309
World Ranking
14171
National Ranking
5974

Overview

Robert L. Jilka is affiliated with the University of Arkansas for Medical Sciences in the United States. Their research primarily focuses on areas within biochemistry, genetics, and molecular biology, as well as medicine. The main subfields of study encompass molecular biology, physiology, cancer research, endocrinology, diabetes and metabolism, and immunology.

The scientist's research addresses various topics, including:

  • Bone Metabolism and Diseases
  • Adipose Tissue and Metabolism
  • Alkaline Phosphatase Research Studies
  • RNA Research and Splicing
  • NF-κB Signaling Pathways
  • Bone health and treatments
  • MicroRNA in disease regulation

Robert L. Jilka has contributed to several scientific papers published in peer-reviewed journals. Selected recent publications include:

  • "Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence," 2020, JCI Insight
  • "Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors," 2020, Scientific Reports
  • "Increased marrow adipogenesis does not contribute to age-dependent appendicular bone loss in female mice," 2020, Aging Cell
  • "A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice," 2020, Journal of Bone and Mineral Research
  • "Elevation of the unfolded protein response increases RANKL expression," 2020, FASEB BioAdvances

Frequent co-authors collaborating with Robert L. Jilka include:

  • Ha-Neui Kim
  • Maria Almeida
  • Srividhya Iyer
  • Stavros C. Manolagas
  • Elena Ambrogini

The scientist's work has been published in venues such as Scientific Reports, JCI Insight, Aging Cell, Journal of Bone and Mineral Research, and FASEB BioAdvances. Scientific Reports is among the more frequent outlets, with multiple publications appearing there.

Best Publications

  • Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of Osteoporosis

    Stavros C. Manolagas;Robert L. Jilka

  • Increased osteoclast development after estrogen loss: mediation by interleukin-6

    Robert L. Jilka;Giao Hangoc;Giuseppe Girasole;Giovanni Passeri

  • Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity.

    S. Kousteni;T. Bellido;L. I. Plotkin;C. A. O'Brien

  • Matrix-embedded cells control osteoclast formation

    Jinhu Xiong;Melda Onal;Robert L Jilka;Robert S Weinstein

  • Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines

    Robert L. Jilka;Robert S. Weinstein;Teresita Bellido;A. Michael Parfitt

  • Skeletal Involution by Age-associated Oxidative Stress and Its Acceleration by Loss of Sex Steroids

    Maria Almeida;Li Han;Marta Martin-Millan;Lilian I. Plotkin

  • Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2.

    Beata Lecka-Czernik;Igor Gubrij;Elena J. Moerman;Oumitana Kajkenova

  • Interleukin-11: a new cytokine critical for osteoclast development.

    G Girasole;G Passeri;R L Jilka;S C Manolagas

  • Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts

    Xiao Dong Chen;Vladimir Dusevich;Jian Q. Feng;Stavros C. Manolagas

  • Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin.

    Etsuko Abe;Matsuo Yamamoto;Yasuto Taguchi;Beata Lecka‐Czernik

  • Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes

    Charles A O'Brien;Lilian I. Plotkin;Carlo Galli;Joseph J. Goellner

  • Cytokines, bone remodeling, and estrogen deficiency : A 1998 update

    R.L. Jilka

  • Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual

    Maria Almeida;Srividhya Iyer;Marta Martin-Millan;Shoshana M. Bartell

  • FoxO-Mediated Defense against Oxidative Stress in Osteoblasts Is Indispensable for Skeletal Homeostasis in Mice

    Elena Ambrogini;Maria Almeida;Marta Martin-Millan;Ji Hye Paik

  • Increased Lipid Oxidation Causes Oxidative Stress, Increased Peroxisome Proliferator-activated Receptor-γ Expression, and Diminished Pro-osteogenic Wnt Signaling in the Skeleton

    Maria Almeida;Elena Ambrogini;Li Han;Stavros C. Manolagas

  • Rescuing replication and osteogenesis of aged mesenchymal stem cells by exposure to a young extracellular matrix

    Yun Sun;Weiping Li;Zhengding Lu;Richard Chen

  • Reconstitution of marrow-derived extracellular matrix ex vivo: a robust culture system for expanding large-scale highly functional human mesenchymal stem cells.

    Yanlai Lai;Yun Sun;Charles M. Skinner;Eugene L. Son

  • Perspective: Quantifying Osteoblast and Osteocyte Apoptosis: Challenges and Rewards

    Robert L Jilka;Robert S Weinstein;A Michael Parfitt;Stavros C Manolagas

  • FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H 2 O 2 accumulation

    Shoshana M. Bartell;Ha Neui Kim;Elena Ambrogini;Li Han

  • Effect of the purified (Mg2+ + Ca2+)-activated ATPase of sarcoplasmic reticulum upon the passive Ca2+ permeability and ultrastructure of phospholipid vesicles.

    R L Jilka;A N Martonosi;T W Tillack

Frequent Co-Authors

Stavros C. Manolagas
Stavros C. Manolagas University of Arkansas for Medical Sciences
Robert S. Weinstein
Robert S. Weinstein University of Arkansas for Medical Sciences
Teresita Bellido
Teresita Bellido University of Arkansas for Medical Sciences
David V. Cohn
David V. Cohn University of Louisville
Haibo Zhao
Haibo Zhao Huazhong University of Science and Technology
Rafael de Cabo
Rafael de Cabo National Institutes of Health
Daohong Zhou
Daohong Zhou University of Florida
Joseph L. Witztum
Joseph L. Witztum University of California, San Diego
John A. Katzenellenbogen
John A. Katzenellenbogen University of Illinois at Urbana-Champaign
Benita S. Katzenellenbogen
Benita S. Katzenellenbogen University of Illinois at Urbana-Champaign

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