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Biology and Biochemistry

D-Index
55
Citations
10104
World Ranking
15138
National Ranking
6329

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Patricia J. Kiley is affiliated with the University of Wisconsin-Madison in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a notable focus on Molecular Biology, Genetics, Endocrinology, Renewable Energy, Sustainability and the Environment, and Ecology.

The scientist's work concentrates on several main topics, including:

  • Bacterial Genetics and Biotechnology
  • Microbial Metabolic Engineering and Bioproduction
  • Yersinia bacterium, plague, ectoparasites research
  • Vibrio bacteria research studies
  • Genomics and Phylogenetic Studies
  • Microbial Community Ecology and Physiology
  • CRISPR and Genetic Engineering

Patricia J. Kiley has published extensively in journals such as mBio, bioRxiv (Cold Spring Harbor Laboratory), PLoS Genetics, Applied and Environmental Microbiology, and Biochimica et Biophysica Acta (BBA) - Molecular Cell Research.

Selected recent publications include:

  • "Tailoring a Global Iron Regulon to a Uropathogen," 2020, mBio
  • "The essential Rhodobacter sphaeroides CenKR two-component system regulates cell division and envelope biosynthesis," 2022, PLoS Genetics
  • "Improving Mobilization of Foreign DNA into Zymomonas mobilis Strain ZM4 by Removal of Multiple Restriction Systems," 2021, Applied and Environmental Microbiology
  • "Model-driven analysis of mutant fitness experiments improves genome-scale metabolic models of Zymomonas mobilis ZM4," 2020, PLoS Computational Biology
  • "A Diverged Transcriptional Network for Usage of Two Fe-S Cluster Biogenesis Machineries in the Delta-Proteobacterium Myxococcus xanthus," 2023, mBio

Frequent co-authors collaborating with Patricia J. Kiley include:

  • Erin L. Mettert
  • Kevin S. Myers
  • Rajdeep Banerjee
  • Piyush Behari Lal
  • Fritz Wells

In 2020, Patricia J. Kiley was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • IscR, an Fe-S cluster-containing transcription factor, represses expression of Escherichia coli genes encoding Fe-S cluster assembly proteins.

    Christopher J. Schwartz;Jennifer L. Giel;Thomas Patschkowski;Christopher Luther

  • The role of Fe–S proteins in sensing and regulation in bacteria

    Patricia J Kiley;Helmut Beinert

  • Iron-sulfur cluster disassembly in the FNR protein of Escherichia coli by O2: [4Fe-4S] to [2Fe-2S] conversion with loss of biological activity

    Natalia Khoroshilova;Codrina Popescu;Eckard Münck;Helmut Beinert

  • Oxygen sensing by the global regulator, FNR: the role of the iron-sulfur cluster.

    Patricia J. Kiley;Helmut Beinert

  • The cysteine desulfurase, IscS, has a major role in in vivo Fe-S cluster formation in Escherichia coli.

    Christopher J. Schwartz;Ouliana Djaman;James A. Imlay;Patricia J. Kiley

  • DNA Binding and Dimerization of the Fe−S-containing FNR Protein from Escherichia coli Are Regulated by Oxygen

    Beth A. Lazazzera;Helmut Beinert;Natalia Khoroshilova;Mary Claire Kennedy

  • Genome-Wide Expression Analysis Indicates that FNR of Escherichia coli K-12 Regulates a Large Number of Genes of Unknown Function

    Yisheng Kang;K. Derek Weber;Yu Qiu;Patricia J. Kiley

  • IscR‐dependent gene expression links iron‐sulphur cluster assembly to the control of O2‐regulated genes in Escherichia coli

    Jennifer L. Giel;Dmitry Rodionov;Mingzhu Liu;Frederick R. Blattner

  • Molecular genetics of photosynthetic membrane biosynthesis in Rhodobacter sphaeroides.

    P J Kiley;S Kaplan

  • Fe-S proteins in sensing and regulatory functions.

    Helmut Beinert;Patricia J Kiley

  • Association of a polynuclear iron-sulfur center with a mutant FNR protein enhances DNA binding.

    Natalia Khoroshilova;Helmut Beinert;Patricia J. Kiley

  • Characterization of the lipopolysaccharide from Actinobacillus actinomycetemcomitans Y4 and N27.

    P Kiley;S C Holt

  • Identification of a contact site for different transcription activators in region 4 of the Escherichia coli RNA polymerase sigma70 subunit.

    Michael A Lonetto;Virgil Rhodius;Karin Lamberg;Patricia Kiley

  • Genome-scale analysis of escherichia coli FNR reveals complex features of transcription factor binding.

    Kevin S. Myers;Huihuang Yan;Irene M. Ong;Dongjun Chung

  • The activity of the Escherichia coli transcription factor FNR is regulated by a change in oligomeric state.

    B A Lazazzera;D M Bates;P J Kiley

  • Correcting direct effects of ethanol on translation and transcription machinery confers ethanol tolerance in bacteria.

    Rembrandt J. F. Haft;David H. Keating;Tyler Schwaegler;Michael S. Schwalbach

  • The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally

    Dan M. Park;Md. Sohail Akhtar;Aseem Z. Ansari;Robert Landick;Robert Landick

  • Exploiting thiol modifications.

    Patricia J Kiley;Gisela Storz

  • Regulation of iron-sulphur cluster homeostasis through transcriptional control of the Isc pathway by [2Fe-2S]-IscR in Escherichia coli.

    Jennifer L. Giel;April D. Nesbit;Erin L. Mettert;Angela S. Fleischhacker

  • Mössbauer spectroscopy as a tool for the study of activation/inactivation of the transcription regulator FNR in whole cells of Escherichia coli

    Codrina V. Popescu;Donna M. Bates;Helmut Beinert;Eckard Münck

Frequent Co-Authors

Robert Landick
Robert Landick University of Wisconsin–Madison
Helmut Beinert
Helmut Beinert University of Wisconsin–Madison
Jennifer L. Reed
Jennifer L. Reed University of Wisconsin–Madison
Eckard Münck
Eckard Münck Carnegie Mellon University
Timothy J. Donohue
Timothy J. Donohue University of Wisconsin–Madison
Nicole T. Perna
Nicole T. Perna University of Wisconsin–Madison
Samuel Kaplan
Samuel Kaplan The University of Texas Health Science Center at Houston
Joshua J. Coon
Joshua J. Coon University of Wisconsin–Madison
Mark Goulian
Mark Goulian University of Pennsylvania
Gisela Storz
Gisela Storz National Institutes of Health

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