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D-Index & Metrics

Genetics

D-Index
50
Citations
21715
World Ranking
3895
National Ranking
1680

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Nicholas Navin is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research is centered primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Key subfields include Molecular Biology, Cancer Research, Oncology, Genetics, and Pulmonary and Respiratory Medicine.

The scientist's work focuses heavily on Cancer Genomics and Diagnostics, as well as Single-cell and spatial transcriptomics. Other notable research topics include Cancer Cells and Metastasis, Immune cells in cancer, Ferroptosis and cancer prognosis, Glioma Diagnosis and Treatment, and Epigenetics and DNA Methylation.

Recent publications by Nicholas Navin demonstrate active contributions to cancer biology and single-cell genomics. Selected papers include:

  • Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes, 2021, Nature Biotechnology
  • Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics, 2020, Nature Communications
  • Advancing Cancer Research and Medicine with Single-Cell Genomics, 2020, Cancer Cell
  • Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells, 2020, The Journal of Experimental Medicine
  • Breast tumours maintain a reservoir of subclonal diversity during expansion, 2021, Nature

Frequent coauthors collaborating with Nicholas Navin include Emi Sei, Shanshan Bai, Ken Chen, Alastair M. Thompson, and Jianzhuo Li.

The scientist regularly publishes in several venues, with Cancer Research being the most frequent, followed by bioRxiv (Cold Spring Harbor Laboratory), Blood, Nature Communications, and Neuro-Oncology.

Nicholas Navin was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

  • Large-Scale Copy Number Polymorphism in the Human Genome

    Jonathan Sebat;B. Lakshmi;Jennifer Troge;Joan Alexander

  • Tumour evolution inferred by single-cell sequencing

    Nicholas E Navin;Jude Kendall;Jennifer Troge;Peter M Andrews

  • Clonal evolution in breast cancer revealed by single nucleus genome sequencing

    Yong Wang;Jill Waters;Marco L. Leung;Anna Unruh

  • Toward understanding and exploiting tumor heterogeneity

    Ash A Alizadeh;Victoria Aranda;Alberto Bardelli;Cedric Blanpain

  • Inferring tumor progression from genomic heterogeneity

    Nicholas Navin;Alexander Krasnitz;Linda Rodgers;Kerry Cook

  • Advances and applications of single-cell sequencing technologies.

    Yong Wang;Nicholas E. Navin

  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution

    Orit Rozenblatt-Rosen;Aviv Regev;Aviv Regev;Aviv Regev;Philipp Oberdoerffer;Tal Nawy

  • WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus

    Akihiko Komuro;Makoto Nagai;Nicholas E. Navin;Marius Sudol

  • Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes.

    Ruli Gao;Ruli Gao;Shanshan Bai;Ying C. Henderson;Yiyun Lin

  • Punctuated copy number evolution and clonal stasis in triple-negative breast cancer

    Ruli Gao;Alexander Davis;Thomas O. McDonald;Emi Sei

  • Genome-wide copy number analysis of single cells.

    Timour Baslan;Jude Kendall;Linda Rodgers;Hilary Cox

  • The first five years of single-cell cancer genomics and beyond

    Nicholas E. Navin

  • Novel patterns of genome rearrangement and their association with survival in breast cancer

    James Hicks;Alexander Krasnitz;B. Lakshmi;Nicholas E. Navin

  • Tumor evolution: Linear, branching, neutral or punctuated?☆

    Alexander Davis;Ruli Gao;Nicholas Navin

  • Cancer genomics: one cell at a time.

    Nicholas E Navin;Nicholas E Navin

  • Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells.

    Teresa Manzo;Teresa Manzo;Boone M. Prentice;Kristin G. Anderson;Kristin G. Anderson;Ayush Raman

  • Insight into the heterogeneity of breast cancer through next-generation sequencing

    Hege G. Russnes;Nicholas Navin;James Hicks;Anne Lise Borresen-Dale

  • Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.

    Kiyomi Morita;Kiyomi Morita;Feng Wang;Katharina Jahn;Katharina Jahn;Tianyuan Hu

  • Future medical applications of single-cell sequencing in cancer

    Nicholas E Navin;James Hicks

  • Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer.

    Marco L. Leung;Alexander Davis;Ruli Gao;Anna Casasent

Frequent Co-Authors

Ken Chen
Ken Chen The University of Texas MD Anderson Cancer Center
James W. Hicks
James W. Hicks University of Southern California
Michael Wigler
Michael Wigler Cold Spring Harbor Laboratory
Funda Meric-Bernstam
Funda Meric-Bernstam The University of Texas MD Anderson Cancer Center
Luay Nakhleh
Luay Nakhleh Rice University
Michael Andreeff
Michael Andreeff The University of Texas MD Anderson Cancer Center
Jianhua Zhang
Jianhua Zhang The University of Texas MD Anderson Cancer Center
Christopher J. Logothetis
Christopher J. Logothetis The University of Texas MD Anderson Cancer Center
Marina Konopleva
Marina Konopleva The University of Texas MD Anderson Cancer Center
Li Ding
Li Ding Washington University in St. Louis

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