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Medicine

D-Index
89
Citations
30517
World Ranking
12658
National Ranking
6475

Research.com Recognitions

  • The Science Academy Society of Turkey - Bilim Akademisi Pediatric Infectious Diseases
  • Member of the Association of American Physicians
  • The Science Academy Society of Turkey - Bilim Akademisi Pediatric Infectious Diseases
  • Member of the Association of American Physicians

Overview

Moshe Arditi is affiliated with Cedars-Sinai Medical Center in the United States. Their research spans a broad spectrum of medical disciplines, focusing extensively on infectious diseases and immunology within the context of pediatric and cardiovascular conditions.

The primary fields of study for Arditi include Medicine, with a strong emphasis on Surgery, Infectious Diseases, and Immunology. This multidisciplinary approach is reflected in their subfield research, which also covers Molecular Biology and Pulmonary and Respiratory Medicine.

The main topics of Arditi's work highlight an in-depth exploration of the following areas:

  • Kawasaki Disease and Coronary Complications
  • Inflammasome and Immune Disorders
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Coronary Artery Anomalies
  • Vasculitis and Related Conditions
  • Immune Responses and Vaccinations

Arditi's publication record includes frequent contributions to prominent journals and venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Frontiers in Immunology
  • The Journal of Immunology
  • Journal of Clinical Investigation

Notable recent publications include:

  • "Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation," 2020, Proceedings of the National Academy of Sciences
  • "Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation," 2021, Immunity
  • "C9orf72 in myeloid cells suppresses STING-induced inflammation," 2020, Nature
  • "Kawasaki disease: pathophysiology and insights from mouse models," 2020, Nature Reviews Rheumatology
  • "Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier," 2021, Journal of Clinical Investigation

Arditi works collaboratively with several frequent co-authors, including:

  • Magali Noval Rivas
  • Timothy R. Crother
  • Rebecca A. Porritt
  • Kenichi Shimada
  • Youngho Lee

Among the distinctions received, Arditi was awarded recognition by The Science Academy Society of Turkey for contributions to Pediatric Infectious Diseases and holds membership in the Association of American Physicians.

Best Publications

  • Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

    Kenichi Shimada;Timothy R. Crother;Justin Karlin;Jargalsaikhan Dagvadorj

  • Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

    Kathrin S. Michelsen;Michelle H. Wong;Prediman K. Shah;Wenxuan Zhang

  • Decreased Expression of Toll-Like Receptor-4 and MD-2 Correlates with Intestinal Epithelial Cell Protection Against Dysregulated Proinflammatory Gene Expression in Response to Bacterial Lipopolysaccharide

    Maria T. Abreu;Puja Vora;Emmanuelle Faure;Lisa S. Thomas

  • Toll-Like Receptor-4 Is Expressed by Macrophages in Murine and Human Lipid-Rich Atherosclerotic Plaques and Upregulated by Oxidized LDL

    Xiaoou Helen Xu;Prediman K. Shah;Emmanuelle Faure;Ozlem Equils

  • Bacterial Lipopolysaccharide Activates NF-κB through Toll-like Receptor 4 (TLR-4) in Cultured Human Dermal Endothelial Cells DIFFERENTIAL EXPRESSION OF TLR-4 AND TLR-2 IN ENDOTHELIAL CELLS

    Emmanuelle Faure;Ozlem Equils;Peter A. Sieling;Lisa Thomas

  • TLR Signaling in the Gut in Health and Disease

    Maria T. Abreu;Masayuki Fukata;Moshe Arditi

  • Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes

    Frank X. Zhang;Carsten J. Kirschning;Roberta Mancinelli;Xiao Ping Xu

  • Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

    Masayuki Fukata;Kathrin S. Michelsen;Rajaraman Eri;Lisa S. Thomas

  • Human Intestinal Epithelial Cells Are Broadly Unresponsive to Toll-Like Receptor 2-Dependent Bacterial Ligands: Implications for Host-Microbial Interactions in the Gut

    Gil Melmed;Lisa S. Thomas;Nahee Lee;Samuel Y. Tesfay

  • Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

    Masayuki Fukata;Anli Chen;Arielle Klepper;Suneeta Krishnareddy

  • TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells.

    Maria T. Abreu;Elizabeth T. Arnold;Lisa S. Thomas;Rivkah Gonsky

  • β-Defensin-2 Expression Is Regulated by TLR Signaling in Intestinal Epithelial Cells

    Puja Vora;Adrienne Youdim;Lisa S. Thomas;Masayuki Fukata

  • HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression

    James F Curtin;James F Curtin;Naiyou Liu;Naiyou Liu;Marianela Candolfi;Marianela Candolfi;Weidong Xiong;Weidong Xiong

  • Three-Year Multicenter Surveillance of Pneumococcal Meningitis in Children: Clinical Characteristics, and Outcome Related to Penicillin Susceptibility and Dexamethasone Use

    Moshe Arditi;Edward O. Mason;John S. Bradley;Tina Q. Tan

  • Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.

    Hongxu Xian;Yuan Liu;Alexandra Rundberg Nilsson;Raphaella Gatchalian

  • Distinct Mutations in IRAK-4 Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections

    Andrei E. Medvedev;Arnd Lentschat;Arnd Lentschat;Douglas B. Kuhns;Jorge C.G. Blanco

  • TLR signaling: an emerging bridge from innate immunity to atherogenesis.

    Kathrin S. Michelsen;Terence M. Doherty;Prediman K. Shah;Moshe Arditi

  • Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid.

    Kelly S. Doran;Erin J. Engelson;Arya Khosravi;Heather C. Maisey

  • Three-year multicenter surveillance of systemic pneumococcal infections in children

    Sheldon L. Kaplan;Edward O. Mason;William J. Barson;Ellen R. Wald

  • Innate immunity and toll-like receptors: clinical implications of basic science research

    Maria T. Abreu;Moshe Arditi

Frequent Co-Authors

Ram Yogev
Ram Yogev Northwestern University
Edward O. Mason
Edward O. Mason Baylor College of Medicine
John S. Bradley
John S. Bradley University of California, San Diego
Ellen R. Wald
Ellen R. Wald University of Wisconsin–Madison
Tina Q. Tan
Tina Q. Tan Northwestern University
Monique F. Stins
Monique F. Stins Johns Hopkins University
Sheldon L. Kaplan
Sheldon L. Kaplan Baylor College of Medicine
Stanford T. Shulman
Stanford T. Shulman Northwestern University
Nemani V. Prasadarao
Nemani V. Prasadarao University of Southern California

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