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Biology and Biochemistry

D-Index
59
Citations
11676
World Ranking
12618
National Ranking
5390

Overview

Louis M. Pelus is affiliated with Indiana University in the United States and has a research focus primarily in the field of medicine, with significant contributions to hematology. Their work spans several subfields including radiology, nuclear medicine and imaging, genetics, oncology, and immunology.

The scientist's research centres on topics such as hematopoietic stem cell transplantation, effects of radiation exposure, acute myeloid leukemia research, mesenchymal stem cell research, erythrocyte function and pathophysiology, chemokine receptors and signaling, and immunotherapy and immune responses.

Louis M. Pelus has published extensively, with frequent appearances in the following venues:

  • Radiation Research
  • Stem Cell Reviews and Reports
  • Methods in Molecular Biology
  • Stem Cells
  • Stem Cell Reports

Frequent co-authors include Christie M. Orschell, P. Artur Plett, Pratibha Singh, Carol H. Sampson, and Andrea M. Patterson.

Some of the recent papers involving Louis M. Pelus include:

  • "CXCR4 expression in the bone marrow microenvironment is required for hematopoietic stem and progenitor cell maintenance and early hematopoietic regeneration after myeloablation" (2020, Stem Cells)
  • "A Single Radioprotective Dose of Prostaglandin E2 Blocks Irradiation-Induced Apoptotic Signaling and Early Cycling of Hematopoietic Stem Cells" (2020, Stem Cell Reports)
  • "Age and Sex Divergence in Hematopoietic Radiosensitivity in Aged Mouse Models of the Hematopoietic Acute Radiation Syndrome" (2022, Radiation Research)
  • "Aging-Related Reduced Expression of CXCR4 on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects" (2020, Stem Cell Reviews and Reports)
  • "Optimizing and Profiling Prostaglandin E2 as a Medical Countermeasure for the Hematopoietic Acute Radiation Syndrome" (2020, Radiation Research)

Best Publications

  • Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation.

    Jonathan Hoggatt;Pratibha Singh;Janardhan Sampath;Louis M. Pelus

  • Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.

    Charlie R. Mantel;Heather A. O'Leary;Brahmananda R. Chitteti;Xinxin Huang

  • Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation.

    Corey Cutler;Pratik Multani;David Robbins;Haesook T. Kim

  • Role for monocyte-macrophage-derived colony-stimulating factor and prostaglandin E in the positive and negative feedback control of myeloid stem cell proliferation.

    J.I. Kurland;H.E. Broxmeyer;L.M. Pelus;R.S. Bockman

  • Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: implication of survivin expression in normal hematopoiesis.

    Seiji Fukuda;Louis M. Pelus

  • Regulation of macrophage and granulocyte proliferation. Specificities of prostaglandin E and lactoferrin

    Louis M. Pelus;Hal E. Broxmeyer;Jeffrey I. Kurland;Malcolm A. S. Moore

  • Induction of prostaglandin E synthesis in normal and neoplastic macrophages: Role for colony-stimulating factor(s) distinct from effects on myeloid progenitor cell proliferation

    Jeffrey I. Kurland;Louis M. Pelus;Peter Ralph;Richard S. Bockman

  • Differential Chemotactic Behavior of Developing T Cells in Response to Thymic Chemokines

    Chang H. Kim;Louis M. Pelus;John R. White;Hal E. Broxmeyer

  • Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis

    Hal E Broxmeyer;Jonathan Hoggatt;Jonathan Hoggatt;Heather A O'Leary;Charlie Mantel

  • A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor

    Shin Shay Tian;Peter Lamb;Andrew G. King;Stephen G. Miller

  • The antiapoptosis protein survivin is associated with cell cycle entry of normal cord blood CD34(+) cells and modulates cell cycle and proliferation of mouse hematopoietic progenitor cells.

    Seiji Fukuda;Richard G. Foster;Scott B. Porter;Louis M. Pelus

  • SDF-1/CXCL12 Enhances Survival and Chemotaxis of Murine Embryonic Stem Cells and Production of Primitive and Definitive Hematopoietic Progenitor Cells

    Ying Guo;Giao Hangoc;Huimin Bian;Louis M. Pelus

  • Differential Stem and Progenitor Cell Trafficking by Prostaglandin E2

    Jonathan Hoggatt;Khalid S. Mohammad;Pratibha Singh;Amber F. Hoggatt;Amber F. Hoggatt

  • Rapid mobilization of murine hematopoietic stem cells with enhanced engraftment properties and evaluation of hematopoietic progenitor cell mobilization in rhesus monkeys by a single injection of SB-251353, a specific truncated form of the human CXC chemokine GROβ

    Andrew G. King;Dan Horowitz;Susan B. Dillon;Robert Levin

  • Peripheral blood stem cell mobilization: The CXCR2 ligand GROβ rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties

    Louis M. Pelus;Seiji Fukuda

  • Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability.

    Charlie R Mantel;Ying Guo;Man Ryul Lee;Min-Kyoung Kim

  • Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia.

    Eun Ji Gang;Yao-Te Hsieh;Jennifer Pham;Yi Zhao

  • CK beta-11/macrophage inflammatory protein-3 beta/EBI1-ligand chemokine is an efficacious chemoattractant for T and B cells.

    Chang H. Kim;Louis M. Pelus;John R. White;Edward Applebaum

  • Flt3 ligand and the Flt3 receptor regulate hematopoietic cell migration by modulating the SDF-1α(CXCL12)/CXCR4 axis

    Seiji Fukuda;Hal E. Broxmeyer;Louis M. Pelus

  • Phase I trial of recombinant interferon gamma in cancer patients.

    Saroj Vadhan-Raj;Ayad Al-Katib;Ravi Bhalla;Lou Pelus

Frequent Co-Authors

Hal E. Broxmeyer
Hal E. Broxmeyer Indiana University
Seiji Yamaguchi
Seiji Yamaguchi Shimane University
Edward F. Srour
Edward F. Srour Indiana University
Giao Hangoc
Giao Hangoc Indiana University
Chang H. Kim
Chang H. Kim University of Michigan–Ann Arbor
Scott Cooper
Scott Cooper Indiana University
David T. Scadden
David T. Scadden Harvard University
John D. Crispino
John D. Crispino Northwestern University
Markus Müschen
Markus Müschen Yale University
Peter V. Kharchenko
Peter V. Kharchenko Harvard University

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