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D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
9958
World Ranking
18632
National Ranking
7620

Overview

Robert Friesel is affiliated with Maine Medical Center in the United States and has a research portfolio concentrated in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Oncology, Immunology, Genetics, and Pulmonary and Respiratory Medicine.

Their research primarily revolves around topics such as Fibroblast Growth Factor Research, Cytokine Signaling Pathways and Interactions, IL-33, ST2, and ILC Pathways, Cancer Immunotherapy and Biomarkers, Digestive system and related health, Neonatal Respiratory Health Research, and Adipose Tissue and Metabolism.

Friesel's recent publications include the following:

  • Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis (2020) in Oncogene
  • Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling (2021) in Cell Communication and Signaling
  • Sprouty1 regulates gonadal white adipose tissue growth through a PDGFRα/β-Akt pathway (2021) in Adipocyte
  • Sprouty1 has a protective role in atherogenesis and modifies the migratory and inflammatory phenotype of vascular smooth muscle cells (2023) in Atherosclerosis
  • Endothelial IL17RD promotes Western diet-induced aortic myeloid cell infiltration (2024) in Biochemical and Biophysical Research Communications

Frequent co-authors in Friesel's research include:

  • Xuehui Yang
  • Shivangi Pande
  • Lucy Liaw
  • Charlotte Girondel
  • Kim Lévesque

They have published in the following venues:

  • Oncogene
  • Cell Communication and Signaling
  • Adipocyte
  • Atherosclerosis
  • Biochemical and Biophysical Research Communications

Best Publications

  • Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction.

    Robert E. Friesel;Thomas Maciag

  • Heparin binds endothelial cell growth factor, the principal endothelial cell mitogen in bovine brain

    Thomas Maciag;Tevie Mehlman;Robert Friesel;Alain B. Schreiber

  • The Role of Fibroblast Growth Factors in Tumor Growth

    Murray Korc;Robert E. Friesel

  • Interaction of endothelial cell growth factor with heparin: characterization by receptor and antibody recognition.

    Alain B. Schreiber;John Kenney;William J. Kowalski;Robert Friesel

  • Inhibition of Endothelial Cell Proliferation by Gamma-Interferon

    Robert Friesel;Akira Komoriya;Thomas Maciag

  • Human endothelial cells are chemotactic to endothelial cell growth factor and heparin.

    V P Terranova;R DiFlorio;R M Lyall;S Hic

  • Identification of Sef, a novel modulator of FGF signalling.

    Michael Tsang;Robert Friesel;Tetsuhiro Kudoh;Igor B Dawid

  • Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice.

    M L Robinson;P A Overbeek;D J Verran;W E Grizzle

  • Collagen Triple Helix Repeat Containing 1, a Novel Secreted Protein in Injured and Diseased Arteries, Inhibits Collagen Expression and Promotes Cell Migration

    Peter Pyagay;Mélanie Heroult;Qiaozeng Wang;Wolfgang Lehnert

  • Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

    W H Burgess;C A Dionne;J Kaplow;R Mudd

  • Human vascular smooth muscle cells both express and respond to heparin-binding growth factor I (endothelial cell growth factor).

    Jeffrey A. Winkles;Robert Friesel;Wilson H. Burgess;Richard Howk

  • Association of fibroblast growth factor receptor-1 with c-Src correlates with association between c-Src and cortactin.

    Xi Zhan;C. Plourde;Xiaoguo Hu;R. Friesel

  • Ligand-independent Activation of Fibroblast Growth Factor Receptors by Point Mutations in the Extracellular, Transmembrane, and Kinase Domains

    Karen M. Neilson;Robert Friesel;Robert Friesel

  • Constitutive Activation of Fibroblast Growth Factor Receptor-2 by a Point Mutation Associated with Crouzon Syndrome

    Karen M. Neilson;Robert E. Friesel

  • Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.

    Dmitry Kovalenko;Xuehui Yang;Robert J. Nadeau;Robert J. Nadeau;Lauren K. Harkins

  • A Unique Family of Endothelial Cell Polypeptide Mitogens: The Antigenic and Receptor Cross-Reactivity of Bovine Endothelial Cell Growth Factor, Brain-derived Acidic Fibroblast Growth Factor, and Eye-derived Growth Factor-II

    A B Schreiber;J Kenney;J Kowalski;K A Thomas

  • Heparin protects heparin-binding growth factor-I from proteolytic inactivation in vitro.

    Todd K. Rosengart;Warren V. Johnson;Warren V. Johnson;Robert Friesel;Robert Friesel;Richard Clark;Richard Clark

  • Vascular injury induces expression of periostin: implications for vascular cell differentiation and migration.

    Volkhard Lindner;Qiaozeng Wang;Barbara A. Conley;Robert E. Friesel

  • Multiple forms of endothelial cell growth factor. Rapid isolation and biological and chemical characterization.

    W H Burgess;T Mehlman;R Friesel;W V Johnson

  • An angiogenic growth factor is expressed in human glioma cells.

    T A Libermann;R Friesel;M Jaye;R M Lyall

Frequent Co-Authors

Lucy Liaw
Lucy Liaw Maine Medical Center
Calvin P.H. Vary
Calvin P.H. Vary Maine Medical Center
Thomas Maciag
Thomas Maciag Maine Medical Center
Wilson H. Burgess
Wilson H. Burgess American Red Cross
Clifford J. Rosen
Clifford J. Rosen Maine Medical Center
Jeffrey A. Winkles
Jeffrey A. Winkles University of Maryland, Baltimore
Igor B. Dawid
Igor B. Dawid National Institutes of Health
Naphtali Savion
Naphtali Savion Tel Aviv University
Rosemary L. Smith
Rosemary L. Smith University of Maine
Robert J. Desnick
Robert J. Desnick Icahn School of Medicine at Mount Sinai

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