World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
21574
World Ranking
6913
National Ranking
3189

Overview

Lee Niswander is affiliated with the University of Colorado Boulder in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant work also conducted in the field of medicine. Niswander's research encompasses several specific subfields including molecular biology, genetics, rheumatology, pediatrics, perinatology, child health, and public health, environmental and occupational health.

Their work covers multiple research topics such as epigenetics and DNA methylation, folate and B vitamins research, genetics and neurodevelopmental disorders, hedgehog signaling pathway studies, Wnt/β-catenin signaling in development and cancer, developmental biology and gene regulation, as well as genetic and kidney cyst diseases.

Lee Niswander has contributed to several peer-reviewed papers, published in reputable journals over recent years. Some of the notable publications include:

  • TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction, 2020, Frontiers in Cell and Developmental Biology
  • Mutations in KIF7 implicated in idiopathic scoliosis in humans and axial curvatures in zebrafish, 2020, Human Mutation
  • Association between rare variants in specific functional pathways and human neural tube defects multiple subphenotypes, 2020, Neural Development
  • Micronutrient imbalance and common phenotypes in neural tube defects, 2021, genesis
  • Pathogenesis of neural tube defects: The regulation and disruption of cellular processes underlying neural tube closure, 2022, WIREs Mechanisms of Disease

The scientist frequently collaborates with several co-authors, indicating a networked approach to research. Frequent collaborators include:

  • Huili Li
  • Stephen A. Murray
  • Anne L. Calof
  • Arthur D. Lander
  • Anneke Dixie Kakebeen

Lee Niswander's work has been published repeatedly in several prominent venues. These include:

  • Developmental Biology
  • FASEB BioAdvances
  • genesis
  • Development
  • Scientific Data

Best Publications

  • Hedgehog signalling in the mouse requires intraflagellar transport proteins

    Danwei Huangfu;Aimin Liu;Aimin Liu;Andrew S. Rakeman;Andrew S. Rakeman;Noel S. Murcia

  • A positive feedback loop coordinates growth and patterning in the vertebrate limb

    Lee Niswander;Susan Jeffrey;Gail R. Martin;Cheryll Tickle

  • Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

    L. Niswander;G.R. Martin

  • FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb

    Lee Niswander;Cheryll Tickle;Astrid Vogel;Iain Booth

  • Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage.

    Hongyan Zou;Rotraud Wieser;Joan Massagué;Lee Niswander

  • Requirement for BMP Signaling in Interdigital Apoptosis and Scale Formation

    Hongyan Zou;Lee Niswander

  • Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors.

    Aimin Liu;Baolin Wang;Lee A. Niswander

  • FGF-4 and BMP-2 have opposite effects on limb growth

    Lee Niswander;Gail R. Martin

  • The Continuing Challenge of Understanding, Preventing, and Treating Neural Tube Defects

    John B. Wallingford;Lee A. Niswander;Gary M. Shaw;Richard H. Finnell

  • β-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse

    Radhika Atit;Sema K. Sgaier;Othman A. Mohamed;Makoto M. Taketo

  • Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: Dorsal signals regulate anteroposterior patterning

    Yingzi Yang;Yingzi Yang;Lee Niswander;Lee Niswander

  • LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction.

    Scott D. Weatherbee;Kathryn V. Anderson;Lee A. Niswander

  • Bone morphogenetic protein signalling and vertebrate nervous system development

    Aimin Liu;Aimin Liu;Lee A. Niswander;Lee A. Niswander

  • BMPs Are Required at Two Steps of Limb Chondrogenesis: Formation of Prechondrogenic Condensations and Their Differentiation into Chondrocytes

    Sandrine Pizette;Lee Niswander

  • Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb

    Y Yang;G Drossopoulou;P T Chuang;D Duprez

  • HOMOZYGOUS WNT3 MUTATION CAUSES TETRA-AMELIA IN A LARGE CONSANGUINEOUS FAMILY

    Stephan Niemann;Chengfeng Zhao;Filon Pascu;Ulrich Stahl

  • BMP signaling patterns the dorsal and intermediate neural tube via regulation of homeobox and helix-loop-helix transcription factors

    John R. Timmer;Charlotte Wang;Lee Niswander

  • The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation

    Anita Becker-Heck;Irene E Zohn;Irene E Zohn;Noriko Okabe;Andrew Pollock

  • Plzf regulates limb and axial skeletal patterning

    Maria Barna;Nicola Hawe;Lee Niswander;Pier Paolo Pandolfi

  • BMPs negatively regulate structure and function of the limb apical ectodermal ridge

    Sandrine Pizette;Lee Niswander

Frequent Co-Authors

Kathryn V. Anderson
Kathryn V. Anderson Memorial Sloan Kettering Cancer Center
Gail R. Martin
Gail R. Martin University of California, San Francisco
Terry Magnuson
Terry Magnuson University of North Carolina at Chapel Hill
Cheryll Tickle
Cheryll Tickle University of Bath
Trevor Williams
Trevor Williams Texas A&M University
Richard R. Behringer
Richard R. Behringer The University of Texas MD Anderson Cancer Center
Kenneth L. Jones
Kenneth L. Jones University of California, San Diego
Joan Massagué
Joan Massagué Memorial Sloan Kettering Cancer Center
Yingzi Yang
Yingzi Yang Harvard University
Gavin Kelsey
Gavin Kelsey Babraham Institute

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