D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 50 Citations 11,768 81 World Ranking 10535 National Ranking 755

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Phosphorylation

Kazumasa Ohashi mostly deals with Cell biology, Lim kinase, Cofilin, Molecular biology and Actin. His work on Growth cone as part of general Cell biology research is frequently linked to Phosphatidylserine, bridging the gap between disciplines. His Lim kinase research is multidisciplinary, relying on both LIMK1 and Phosphorylation.

His Cofilin research incorporates themes from Lamellipodium, Actin remodeling and Arp2/3 complex. The concepts of his Actin remodeling study are interwoven with issues in MDia1 and Actin-binding protein. His research in Molecular biology intersects with topics in Protein kinase A, Receptor, Receptor tyrosine kinase, GAS6 and MAP2K7.

His most cited work include:

  • Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. (1329 citations)
  • Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization (1060 citations)
  • Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop (428 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Cofilin, Lim kinase, Molecular biology and Actin. His work carried out in the field of Cell biology brings together such families of science as Actin remodeling, Lamellipodium, Actin cytoskeleton and Cytoskeleton. His research investigates the connection between Actin remodeling and topics such as MDia1 that intersect with problems in Actin-binding protein.

Kazumasa Ohashi combines subjects such as Cofilin 1, Phosphatase, Dephosphorylation, Cell migration and Mitosis with his study of Cofilin. In his work, Alternative splicing and Gene knockdown is strongly intertwined with LIMK1, which is a subfield of Lim kinase. His studies deal with areas such as In situ hybridization, Receptor tyrosine kinase, Protein kinase A and MAP2K7 as well as Molecular biology.

He most often published in these fields:

  • Cell biology (71.58%)
  • Cofilin (35.79%)
  • Lim kinase (30.53%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (71.58%)
  • RHOA (10.53%)
  • Actin (26.32%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cell biology, RHOA, Actin, Cytoskeleton and Mechanotransduction. His Cell biology research focuses on subjects like Keratin, which are linked to Guanine nucleotide exchange factor. His RHOA research includes elements of Collective migration and Myosin.

His Myosin research includes themes of Cell junction, A549 cell and Actin remodeling. He focuses mostly in the field of Cytoskeleton, narrowing it down to matters related to Cell adhesion and, in some cases, GTPase, Tissue homeostasis, Signal transduction and Mechanobiology. As part of the same scientific family, Kazumasa Ohashi usually focuses on Mechanotransduction, concentrating on Stress fiber and intersecting with Myosin light-chain kinase and Morphogenesis.

Between 2016 and 2021, his most popular works were:

  • Roles of the cytoskeleton, cell adhesion and rho signalling in mechanosensing and mechanotransduction. (79 citations)
  • Solo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells. (12 citations)
  • Keratin-binding ability of the N-terminal Solo domain of Solo is critical for its function in cellular mechanotransduction. (8 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Phosphorylation

His primary areas of investigation include Cell biology, Keratin, Actin, Mechanotransduction and Cytoskeleton. The Cell biology study combines topics in areas such as Morphogenesis and Keratin 18. Kazumasa Ohashi has included themes like Myosin light-chain kinase and Myosin in his Morphogenesis study.

His Cytoskeleton research integrates issues from Cytoplasm and Keratin 8. His RHOA research incorporates elements of Hemidesmosome, Intermediate filament, Keratin Filament and Guanine nucleotide exchange factor. Kazumasa Ohashi has researched GTPase in several fields, including Tissue homeostasis, Signal transduction, Cell adhesion and Mechanobiology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

Midori Maekawa;Toshimasa Ishizaki;Shuken Boku;Naoki Watanabe.
Science (1999)

1795 Citations

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

Neng Yang;Osamu Higuchi;Kazumasa Ohashi;Kyoko Nagata.
Nature (1998)

1423 Citations

Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop

Kazumasa Ohashi;Kyoko Nagata;Midori Maekawa;Toshimasa Ishizaki.
Journal of Biological Chemistry (2000)

594 Citations

Identification of the Product of Growth Arrest-specific Gene 6 as a Common Ligand for Axl, Sky, and Mer Receptor Tyrosine Kinases

Kyoko Nagata;Kazumasa Ohashi;Toru Nakano;Hitoshi Arita.
Journal of Biological Chemistry (1996)

525 Citations

Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse.

Hiroyuki Aizawa;Hiroyuki Aizawa;Shuji Wakatsuki;Ai Ishii;Kenji Moriyama.
Nature Neuroscience (2001)

409 Citations

A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons

Haruhiko Bito;Tomoyuki Furuyashiki;Hisamitsu Ishihara;Yoshikazu Shibasaki.
Neuron (2000)

368 Citations

Peroxisome Targeting Signal Type 1 (PTS1) Receptor Is Involved in Import of Both PTS1 and PTS2: Studies with PEX5-Defective CHO Cell Mutants

Hidenori Otera;Kanji Okumoto;Keita Tateishi;Yuka Ikoma.
Molecular and Cellular Biology (1998)

267 Citations

Cell adhesion to phosphatidylserine mediated by a product of growth arrest-specific gene 6.

Toru Nakano;Yoshikazu Ishimoto;Junji Kishino;Masato Umeda.
Journal of Biological Chemistry (1997)

263 Citations

Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif.

K. Mizuno;I. Okano;K. Ohashi;K. Nunoue.
Oncogene (1994)

257 Citations

Identification and Characterization of a Novel Family of Serine/Threonine Kinases Containing Two N-terminal LIM Motifs

Ichiro Okano;Junji Hiraoka;Hidenori Otera;Koh Nunoue.
Journal of Biological Chemistry (1995)

255 Citations

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