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Biology and Biochemistry

D-Index
49
Citations
8249
World Ranking
18055
National Ranking
7383

Overview

Kathrin Muegge is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology.

The scientist's work covers several subfields, including Molecular Biology, Immunology, Plant Science, and Oncology. Their research topics focus on:

  • Epigenetics and DNA Methylation
  • Genomics and Chromatin Dynamics
  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Advanced biosensing and bioanalysis techniques

Kathrin Muegge's publications have appeared in various scientific venues with multiple contributions. Key frequent publication venues include:

  • Nature Communications
  • Nucleic Acids Research
  • Science Signaling
  • Proceedings of the National Academy of Sciences
  • Seminars in Cell and Developmental Biology

Some of their recent papers highlight a focus on chromatin regulation, genomic stability, and immune system development. Selected recent publications are:

  • LSH mediates gene repression through macroH2A deposition, 2020, Nature Communications
  • Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability, 2020, Science Signaling
  • LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2, 2021, Nucleic Acids Research
  • The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation, 2021, Nature Communications
  • Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination, 2020, Proceedings of the National Academy of Sciences

The scientist frequently collaborates with several co-authors, including:

  • Kai Ni
  • Jianke Ren
  • Yafeng He
  • Xiaoping Xu
  • Richard Finney

Best Publications

  • Lsh, a member of the SNF2 family, is required for genome-wide methylation

    Kathleen Dennis;Tao Fan;Theresa Geiman;Qingsheng Yan

  • A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53.

    Chao Mao;Xiang Wang;Yating Liu;Min Wang

  • Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1

    Kathrin Muegge;Thomas M. Williams;Jeffrey Kant;Michael Karin

  • Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH

    Annette R. Khaled;Kyungjae Kim;Robert Hofmeister;Kathrin Muegge

  • Interleukin-7: physiological roles and mechanisms of action

    R. Hofmeister;A.R. Khaled;N. Benbernou;E. Rajnavolgyi

  • Advanced Applications of RNA Sequencing and Challenges

    Yixing Han;Shouguo Gao;Kathrin Muegge;Wei Zhang

  • Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene

    K Muegge;MP Vila;SK Durum

  • The Trophic Action of IL-7 on Pro-T Cells: Inhibition of Apoptosis of Pro-T1, -T2, and -T3 Cells Correlates with Bcl-2 and Bax Levels and Is Independent of Fas and p53 Pathways

    Kyungjae Kim;Chong-kil Lee;Thomas J. Sayers;Kathrin Muegge

  • Lsh is involved in de novo methylation of DNA

    Heming Zhu;Theresa M Geiman;Sichuan Xi;Qiong Jiang

  • Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization.

    Annette R. Khaled;Andrea N. Moor;Aiqun Q. Li;Kyungjae Kim

  • Lsh, an epigenetic guardian of repetitive elements

    Jiaqiang Huang;Tao Fan;Qingsheng Yan;Heming Zhu

  • Interleukin 7 Receptor Control of T Cell Receptor γ Gene Rearrangement: Role of Receptor-associated Chains and Locus Accessibility

    Scott K. Durum;Serge Candèias;Hiroshi Nakajima;Warren J. Leonard

  • Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells.

    Rabindranath De La Fuente;Claudia Baumann;Tao Fan;Anja Schmidtmann

  • IL-7 Receptor and VDJ Recombination: Trophic Versus Mechanistic Actions

    Serge Candéias;Kathrin Muegge;Scott K Durum

  • DNA methylation in early development

    Theresa M. Geiman;Kathrin Muegge

  • The Interleukin 7 Receptor Is Required for T Cell Receptor γ Locus Accessibility to the V(D)j Recombinase

    Mark S. Schlissel;Scott D. Durum;Kathrin Muegge

  • Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes

    T. M. Geiman;K. Muegge

  • Bax deficiency partially corrects interleukin-7 receptor α deficiency

    Annette R Khaled;Wen Qing Li;Jiaqiang Huang;Terry J Fry

  • Lsh, a modulator of CpG methylation, is crucial for normal histone methylation.

    Qingsheng Yan;Jiaqiang Huang;Tao Fan;Heming Zhu

  • Lsh, a SNF2 family member, is required for normal murine development.

    Theresa M Geiman;Lino Tessarollo;Miriam R Anver;Jeffrey B Kopp

Frequent Co-Authors

Scott K. Durum
Scott K. Durum National Institutes of Health
Howard A. Young
Howard A. Young National Institutes of Health
Ina Dobrinski
Ina Dobrinski University of Calgary
Shuang Liu
Shuang Liu Purdue University West Lafayette
Chong-Kil Lee
Chong-Kil Lee Chungbuk National University
William J. Murphy
William J. Murphy Texas A&M University
Ya Cao
Ya Cao Central South University
Gerald R. Crabtree
Gerald R. Crabtree Stanford University
Joseph R. Ecker
Joseph R. Ecker Salk Institute for Biological Studies
Ryan Lister
Ryan Lister University of Western Australia

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