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D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
7403
World Ranking
18121
National Ranking
7406

Overview

Jim J.-C. Lin is affiliated with the University of Iowa in the United States and focuses research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans multiple subfields including Molecular Biology, Cell Biology, Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and Imaging, and Organic Chemistry.

Their research topics include:

  • Ubiquitin and proteasome pathways
  • 14-3-3 protein interactions
  • Monoclonal and Polyclonal Antibodies Research
  • Hippo pathway signaling and YAP/TAZ
  • Wnt/β-catenin signaling in development and cancer
  • Peptidase Inhibition and Analysis
  • Virus-based gene therapy research

Published papers by Jim J.-C. Lin include:

  • Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart, 2020, Nature Communications
  • A pan-respiratory antiviral chemotype targeting a transient host multi-protein complex, 2024, Open Biology
  • A Pan-Respiratory Antiviral Chemotype Targeting a Host Multi-Protein Complex, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • A rapid degradation of calponin 2 is required for cytokinesis, 2021, American Journal of Physiology-Cell Physiology
  • Small Molecule Protein Assembly Modulators with Pan-Cancer Therapeutic Efficacy, 2022, bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators with whom Jim J.-C. Lin has published multiple works include:

  • Maya Michon
  • Anuradha F. Lingappa
  • Suguna Mallesh
  • Dennis Solas
  • Vishwanath R. Lingappa

The venues where Jim J.-C. Lin's research is commonly published are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Open Biology
  • Nature Communications
  • American Journal of Physiology-Cell Physiology
  • Microbiology Resource Announcements

Best Publications

  • Biochemical characterization of the mammalian stress proteins and identification of two stress proteins as glucose- and Ca2+-ionophore-regulated proteins.

    W J Welch;J I Garrels;G P Thomas;J J Lin

  • A Defect in the Kv Channel-Interacting Protein 2 (KChIP2) Gene Leads to a Complete Loss of Ito and Confers Susceptibility to Ventricular Tachycardia

    Hai-Chien Kuo;Ching-Feng Cheng;Robert B. Clark;Jim J.-C. Lin

  • Specification of Actin Filament Function and Molecular Composition by Tropomyosin Isoforms

    Nicole S. Bryce;Galina Schevzov;Vicki Ferguson;Justin M. Percival

  • Differential expression of tropomyosin forms in the microfilaments isolated from normal and transformed rat cultured cells.

    F Matsumura;J J Lin;S Yamashiro-Matsumura;G P Thomas

  • Tropomyosin Isoforms in Nonmuscle Cells

    Jim J.C Lin;Kerri S. Warren;Dawn D. Wamboldt;Tao Wang

  • Isolation and characterization of tropomyosin-containing microfilaments from cultured cells.

    F Matsumura;S Yamashiro-Matsumura;J J Lin

  • Monoclonal antibodies against chicken tropomyosin isoforms: production, characterization, and application.

    Jim Jung-Ching Lin;Chin-Sheng Chou;Jenny Li-Chun Lin

  • Differential localization of tropomyosin isoforms in cultured nonmuscle cells.

    Jim Jung-Ching Lin;Theresa E. Hegmann;Jenny Li-Chun Lin

  • Tropomyosin isoforms in chicken embryo fibroblasts: purification, characterization, and changes in Rous sarcoma virus-transformed cells.

    Jim Jung-Ching Lin;David M. Helfman;Stephan H. Hughes;Chin-Sheng Chou

  • Complete nucleotide sequence and structural organization of rat cardiac troponin T gene. A single gene generates embryonic and adult isoforms via developmentally regulated alternative splicing.

    Jian Ping Jin;Qi Quan Huang;Horng I. Yeh;Jim J C Lin

  • Rapid purification of mammalian cardiac troponin T and its isoform switching in rat hearts during development.

    Jian-Ping Jin;Jim Jung-Ching Lin

  • Isolation and characterization of cDNA clones encoding embryonic and adult isoforms of rat cardiac troponin T.

    Jian-Ping Jin;Jim Jung-Ching Lin

  • Role of VEGF family members and receptors in coronary vessel formation.

    Robert J. Tomanek;Jennifer S. Holifield;Rebecca S. Reiter;Alexander Sandra

  • Requirement of a novel gene, Xin, in cardiac morphogenesis.

    Da Zhi Wang;Rebecca S. Reiter;Jenny Li Chun Lin;Qin Wang

  • Apical Organelle Discharge by Cryptosporidium parvum Is Temperature, Cytoskeleton, and Intracellular Calcium Dependent and Required for Host Cell Invasion

    Xian Ming Chen;Steven P. O'Hara;Bing Q. Huang;Jeremy B. Nelson

  • In vitro functional characterization of bacterially expressed human fibroblast tropomyosin isoforms and their chimeric mutants.

    Robert E. Novy;James R. Sellers;Li-Fei Liu;Jim Jung-Ching Lin

  • Chicken cardiac myofibrillogenesis studied with antibodies specific for titin and the muscle and nonmuscle isoforms of actin and tropomyosin.

    Susan E. Handel;Marion L. Greaser;Edward Schultz;Seu-Mei Wang

  • Tropomyosin Localization Reveals Distinct Populations of Microfilaments in Neurites and Growth Cones

    Galina Schevzov;Peter Gunning;Peter L. Jeffrey;Connie Temm-Grove

  • Human tropomyosin isoforms in the regulation of cytoskeleton functions.

    Jim Jung Ching Lin;Robbin D. Eppinga;Kerri S. Warren;Keith R. McCrae

  • Loss of mXinα, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects

    Elisabeth A Gustafson-Wagner;Haley W Sinn;Yen-Lin Chen;Da-Zhi Wang

Frequent Co-Authors

Peter W. Gunning
Peter W. Gunning University of New South Wales
Da-Zhi Wang
Da-Zhi Wang Boston Children's Hospital
Edna C. Hardeman
Edna C. Hardeman University of New South Wales
Val C. Sheffield
Val C. Sheffield University of Iowa
David R. Soll
David R. Soll University of Iowa
Chun-Fang Wu
Chun-Fang Wu University of Iowa
Todd E. Scheetz
Todd E. Scheetz University of Iowa
David M. Helfman
David M. Helfman Korea Advanced Institute of Science and Technology
William T. Pu
William T. Pu Boston Children's Hospital
Marcelo B. Soares
Marcelo B. Soares University of Illinois at Peoria

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