David M. Helfman

Overview

Best Publications

• Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors.

  Javier F. Cáceres;Stefan Stamm;David M. Helfman;Adrian R. Krainer

  799
  Citations

• The molecular basis for tropomyosin isoform diversity.

  James P. Lees-Miller;David M. Helfman

  459
  Citations

• Cytoskeletal changes in cell transformation and tumorigenesis.

  Geraldine Pawlak;David M Helfman

  439
  Citations

• Identification of clones that encode chicken tropomyosin by direct immunological screening of a cDNA expression library.

  D M Helfman;J R Feramisco;J C Fiddes;G P Thomas

  435
  Citations

• Co-existence of Vinculin and a Vinculin-like Protein of Higher Molecular Weight in Smooth Muscle*

  J R Feramisco;J E Smart;K Burridge;D M Helfman

  416
  Citations

• Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF.

  Akila Mayeda;D. M. Helfman;A. R. Krainer

  352
  Citations

• A new tropomyosin essential for cytokinesis in the fission yeast S. pombe.

  Mohan K. Balasubramanian;David M. Helfman;Sean M. Hemmingsen

  319
  Citations

• Functional properties of non-muscle tropomyosin isoforms

  Mark F. Pittenger;Jeffrey A. Kazzaz;David M. Helfman

  310
  Citations

• The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain.

  J D Scott;M B Glaccum;M J Zoller;M D Uhler

  307
  Citations

• The metastasis associated protein S100A4: role in tumour progression and metastasis.

  David M Helfman;EJ Kim;E Lukanidin;M Grigorian

  306
  Citations

• Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat beta-tropomyosin gene.

  Charlie Degui Chen;Ryuji Kobayashi;David M. Helfman

  278
  Citations

• Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation.

  D M Helfman;S Cheley;E Kuismanen;L A Finn

  257
  Citations

• Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions.

  David M. Helfman;Esther T. Levy;Christine Berthier;Michael Shtutman

  243
  Citations

• A vertebrate actin-related protein is a component of a multisubunit complex involved in microtubule-based vesicle motility

  James P. Lees-Miller;David M. Helfman;Trina A. Schroer

  229
  Citations

• Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3'-terminal exon.

  Hua Lou;David M. Helfman;Robert F. Gagel;Susan M. Berget

  220
  Citations

• RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility

  Michelle D. Larrea;Feng Hong;Seth A. Wander;Thiago G. da Silva

  208
  Citations

• Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway.

  Sungwoo Lee;Sungwoo Lee;David M. Helfman

  206
  Citations

• Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA.

  George J. Mulligan;Wei Guo;Steven Wormsley;David M Helfman

  193
  Citations

• Tropomyosin isoforms in chicken embryo fibroblasts: purification, characterization, and changes in Rous sarcoma virus-transformed cells.

  Jim Jung-Ching Lin;David M. Helfman;Stephan H. Hughes;Chin-Sheng Chou

  167
  Citations

• A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells.

  Andrei V. Bakin;Alfiya Safina;Cammie Rinehart;Cecilia Daroqui

  165
  Citations