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Immunology

D-Index
44
Citations
6067
World Ranking
4807
National Ranking
64

Overview

Javier Leceta is affiliated with the Complutense University of Madrid in Spain. Their research concentrates on immunology and microbiology, with particular emphasis on fields such as immunology, microbiology, oncology, cellular and molecular neuroscience, and molecular biology.

The scientist's work covers a range of topics primarily related to immune responses and inflammation, antimicrobial peptides and activities, peptidase inhibition and analysis, neuropeptides and animal physiology, immune cell function and interaction, inflammasomes and immune disorders, as well as autoimmune and inflammatory disorders research.

Recent publications by Javier Leceta include:

  • Editorial: Immunoregulation at mucosal surfaces (2022) in Frontiers in Immunology
  • Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis (2021) in Frontiers in Immunology
  • Editorial: Overcoming challenges in mucosal immunity: 2022 (2023) in Frontiers in Immunology
  • Editorial: Community series in immunoregulation at mucosal surfaces volume II (2023) in Frontiers in Immunology

Javier Leceta frequently publishes in the journal Frontiers in Immunology, contributing to multiple articles in this venue.

The scientist collaborates with colleagues including S. Jordan, Christoph S. N. Klose, Rosa del Campo, Marina Garín, and Carmen Conde.

Best Publications

  • Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease.

    Mario Delgado;Catalina Abad;Carmen Martinez;Javier Leceta

  • Therapeutic effects of vasoactive intestinal peptide in the trinitrobenzene sulfonic acid mice model of Crohn's disease

    Catalina Abad;Carmen Martinez;Maria G. Juarranz;Alicia Arranz

  • Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate Cyclase-Activation Polypeptide (PACAP) Protect Mice from Lethal Endotoxemia Through the Inhibition of TNF-α and IL-6

    Mario Delgado;Mario Delgado;Carmen Martinez;David Pozo;Juan R. Calvo

  • Immunology of VIP: A Review and Therapeutical Perspectives

    R.P. Gomariz;C. Martinez;C. Abad;J. Leceta

  • Vasoactive intestinal peptide in the immune system: potential therapeutic role in inflammatory and autoimmune diseases.

    M Delgado;C Abad;C Martinez;M G Juarranz

  • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit endotoxin-induced TNF-alpha production by macrophages: in vitro and in vivo studies.

    Mario Delgado;Mario Delgado;David Pozo;Carmen Martinez;Javier Leceta

  • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide modulate endotoxin-induced IL-6 production by murine peritoneal macrophages.

    Carmen Martínez;Mario Delgado;David Pozo;Javier Leceta

  • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit the production of inflammatory mediators by activated microglia.

    Mario Delgado;Javier Leceta;Doina Ganea

  • PACAP in Immunity and Inflammation

    Mario Delgado;Catalina Abad;Cartmen Martinez;M Guillermo Juarranz

  • Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis

    Yasmina Juarranz;Catalina Abad;Carmen Martinez;Alicia Arranz

  • VIP-PACAP system in immunity: new insights for multitarget therapy.

    R.P. Gomariz;Y. Juarranz;C. Abad;A. Arranz

  • Regulation of VIP production and secretion by murine lymphocytes

    Carmen Martinez;Mario Delgado;Catalina Abad;Rosa P Gomariz

  • Anti-inflammatory role in septic shock of pituitary adenylate cyclase-activating polypeptide receptor

    Carmen Martinez;Catalina Abad;Mario Delgado;Alicia Arranz

  • Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis

    Yossan-Var Tan;Catalina Abad;Robert Lopez;Hongmei Dong

  • Immunobiology of vasoactive intestinal peptide (VIP)

    David Pozo;Mario Delgado;Carmen Martı́nez;Juan M Guerrero

  • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide stimulate the induction of Th2 responses by up-regulating B7.2 expression.

    Mario Delgado;Javier Leceta;Rosa P. Gomariz;Doina Ganea

  • Pituitary Adenylate Cyclase-Activating Polypeptide Inhibits Collagen-Induced Arthritis: An Experimental Immunomodulatory Therapy

    Catalina Abad;Carmen Martinez;Javier Leceta;Rosa P. Gomariz

  • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptides (PACAP27) and PACAP38) protect CD4+CD8+ thymocytes from glucocorticoid-induced apoptosis.

    Mario Delgado;Elvira Garrido;Carmen Martinez;Javier Leceta

  • Anti-inflammatory properties of the type 1 and type 2 vasoactive intestinal peptide receptors: role in lethal endotoxic shock.

    Mario Delgado;Rosa P. Gomariz;Carmen Martinez;Catalina Abad

  • Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP

    Rosa P. Gomariz;Alicia Arranz;Catalina Abad;Marta Torroba

  • Receptors and Transcriptional Factors Involved in the Anti‐Inflammatory Activity of VIP and PACAP

    Javier Leceta;Rosa P. Gomariz;Carmen Martinez;Catalina Abad

Frequent Co-Authors

Rosa P. Gomariz
Rosa P. Gomariz Complutense University of Madrid
Carmen Martinez Mora
Carmen Martinez Mora Complutense University of Madrid
Mario Delgado
Mario Delgado Spanish National Research Council
Agustín G. Zapata
Agustín G. Zapata Complutense University of Madrid
Doina Ganea
Doina Ganea Temple University
Juan R. Calvo
Juan R. Calvo University of Seville
Mario Mellado
Mario Mellado Spanish National Research Council
Carolina Tafalla
Carolina Tafalla Spanish National Research Council
James A. Waschek
James A. Waschek University of California, Los Angeles
José Miguel Rodríguez-Frade
José Miguel Rodríguez-Frade Spanish National Research Council

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