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Gunilla B. Karlsson Hedestam

Gunilla B. Karlsson Hedestam

D-Index & Metrics

Immunology

D-Index
50
Citations
7423
World Ranking
4275
National Ranking
95

Overview

Gunilla B. Karlsson Hedestam is affiliated with the Karolinska Institute in Sweden and has an extensive research portfolio primarily focused on medicine, immunology, and microbiology. Their work spans several important subfields including infectious diseases, immunology, molecular biology, radiology, nuclear medicine, imaging, and virology.

The scientist's research concentrates on key topics such as SARS-CoV-2 and COVID-19 research, T-cell and B-cell immunology, monoclonal and polyclonal antibodies research, HIV research and treatment, immune cell function and interaction, COVID-19 clinical research studies, and SARS-CoV-2 detection and testing.

Frequent publication venues for their research include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • Frontiers in Immunology
  • Nature Communications
  • The Lancet Infectious Diseases

Significant recent papers authored or co-authored by Gunilla B. Karlsson Hedestam include:

  • "An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction," 2020, Nature Communications
  • "Vaccination induces HIV broadly neutralizing antibody precursors in humans," 2022, Science
  • "Immunity to SARS-CoV-2 induced by infection or vaccination," 2021, Journal of Internal Medicine
  • "Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity," 2020, Cell Reports
  • "Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies," 2022, The Lancet Infectious Diseases

Their network of frequent co-authors includes researchers such as Martin Corcoran, Ben Murrell, Daniel J. Sheward, Xaquín Castro Dopico, and Leo Hanke, reflecting collaborative efforts across multiple projects in immunology and infectious disease research.

Best Publications

  • The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus

    Gunilla B. Karlsson Hedestam;Gunilla B. Karlsson Hedestam;Ron A.M. Fouchier;Sanjay Phogat;Dennis R. Burton

  • An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.

    Leo Hanke;Laura Vidakovics Perez;Daniel J. Sheward;Daniel J. Sheward;Hrishikesh Das

  • Vaccination induces HIV broadly neutralizing antibody precursors in humans

    Unknown

  • Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity.

    Martin M. Corcoran;Ganesh E. Phad;Néstor Vázquez Bernat;Christiane Stahl-Hennig

  • Interleukin-21-Producing CD4+ T Cells Promote Type 2 Immunity to House Dust Mites

    Jonathan M. Coquet;Jonathan M. Coquet;Martijn J. Schuijs;Mark J. Smyth;Mark J. Smyth;Kim Deswarte

  • DNA vaccines: recent developments and future possibilities.

    Margaret A Liu;Britta Wahren;Gunilla B Karlsson Hedestam

  • Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection

    Marc D. Panas;Margus Varjak;Aleksei Lulla;Kai Er Eng

  • Immunity to SARS-CoV-2 induced by infection or vaccination.

    Xaquin Castro Dopico;Sebastian Ols;Karin Loré;Gunilla B Karlsson Hedestam

  • A novel quantitative flow cytometry-based assay for autophagy.

    Kai Er Eng;Marc D. Panas;Gunilla B. Karlsson Hedestam;Gerald M. McInerney

  • Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP

    Martin Högbom;Ruairi Collins;Susanne van den Berg;Rose-Marie Jenvert

  • Neutralisation sensitivity of the SARS-CoV-2 omicron (B.1.1.529) variant: a cross-sectional study

    Unknown

  • Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

    Sebastian Ols;Lifei Yang;Elizabeth A. Thompson;Pradeepa Pushparaj

  • Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.

    Viktoriya Dubrovskaya;Karen Tran;Gabriel Ozorowski;Javier Guenaga

  • Semliki Forest Virus Nonstructural Protein 2 Is Involved in Suppression of the Type I Interferon Response

    Lucy Breakwell;Pia Dosenovic;Pia Dosenovic;Gunilla B. Karlsson Hedestam;Gunilla B. Karlsson Hedestam;Mauro D'Amato

  • High-Resolution Definition of Vaccine-Elicited B Cell Responses Against the HIV Primary Receptor Binding Site

    Christopher Sundling;Yuxing Li;Nick Huynh;Christian Poulsen

  • Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

    Christopher Sundling;Mattias N.E. Forsell;Sijy O'Dell;Yu Feng

  • MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses

    Ming Zeng;Zeping Hu;Xiaolei Shi;Xiaohong Li

  • PPAR-γ promotes type 2 immune responses in allergy and nematode infection

    Ting Chen;Christopher A. Tibbitt;Xiaogang Feng;Julian M. Stark

  • Human B Cell Responses to TLR Ligands Are Differentially Modulated by Myeloid and Plasmacytoid Dendritic Cells

    Iyadh Douagi;Cornelia Gujer;Christopher Sundling;William C. Adams

  • Heterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant.

    Javier Guenaga;Pia Dosenovic;Gilad Ofek;David Baker

  • A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity

    Carrie N. Arnold;Elaine Pirie;Pia Dosenovic;Gerald M. McInerney

  • Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach

    Paola Martinez-Murillo;Karen Tran;Javier Guenaga;Gustaf Lindgren

  • Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

    Karen Tran;Christian Poulsen;Javier Guenaga;Natalia de Val

Frequent Co-Authors

Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
John R. Mascola
John R. Mascola ModeX Therapeutics
Karin Loré
Karin Loré Karolinska Institute
Sijy O'Dell
Sijy O'Dell National Institute of Allergy and Infectious Diseases
Ben Murrell
Ben Murrell Karolinska Institute
Bruce Beutler
Bruce Beutler The University of Texas Southwestern Medical Center
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Krisha McKee
Krisha McKee National Institute of Allergy and Infectious Diseases
Jan Albert
Jan Albert Karolinska Institute
Peter Liljeström
Peter Liljeström Karolinska Institute

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