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Medicine

D-Index
72
Citations
26196
World Ranking
19771
National Ranking
667

Overview

Alexis Laurent is affiliated with Université Paris Cité in France and specializes in medical research with a focus on hepatology, surgery, oncology, and related subfields.

Their research primarily addresses liver diseases including hepatocellular carcinoma and other hepatic and biliary cancers. The main topics of their work include:

  • Hepatocellular carcinoma treatment and prognosis
  • Cholangiocarcinoma and gallbladder cancer studies
  • Pancreatic and hepatic oncology research
  • Liver disease diagnosis and treatment
  • Gallbladder and bile duct disorders
  • Liver disease and transplantation
  • Diverticular disease and complications

Laurent's research spans several fields of study, predominantly in medicine, with a focus on:

  • Surgery
  • Hepatology
  • Oncology
  • Pulmonary and respiratory medicine
  • Epidemiology

The frequent publication venues for their work include:

  • HPB
  • Journal of Hepatology
  • Surgery
  • Surgical Endoscopy
  • Cancers

Several recent papers illustrate the focus of their scholarship, such as:

  • "Predicting Survival After Hepatocellular Carcinoma Resection Using Deep Learning on Histological Slides," published in Hepatology in 2020
  • "Multiphase Liver MRI for Identifying the Macrotrabecular-Massive Subtype of Hepatocellular Carcinoma," published in Radiology in 2020
  • "Artificial intelligence predicts immune and inflammatory gene signatures directly from hepatocellular carcinoma histology," published in Journal of Hepatology in 2022
  • "Early Hepatic Lesions Display Immature Tertiary Lymphoid Structures and Show Elevated Expression of Immune Inhibitory and Immunosuppressive Molecules," published in Clinical Cancer Research in 2020
  • "Laparoscopic repeat liver resection for hepatocellular carcinoma: a multicentre propensity score-based study," published in British Journal of Surgery in 2020

Laurent has collaborated extensively with several researchers, frequently co-authoring work with:

  • Daniel Cherqui
  • Danièle Sommacale
  • Raffaele Brustia
  • Julien Caldéraro
  • Giuliana Amaddeo

This profile reflects a strong focus on surgical and clinical research relevant to liver cancer and related diseases, highlighting the integration of advanced diagnostic and treatment approaches such as artificial intelligence and laparoscopic surgery.

Best Publications

  • The international position on laparoscopic liver surgery: The Louisville Statement, 2008.

    Joseph F. Buell;Daniel Cherqui;David A. Geller;Nicholas O'Rourke

  • Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

    Kornelius Schulze;Sandrine Imbeaud;Eric Letouzé;Ludmil B. Alexandrov;Ludmil B. Alexandrov

  • Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

    Cécile Guichard;Giuliana Amaddeo;Giuliana Amaddeo;Sandrine Imbeaud;Sandrine Imbeaud;Yannick Ladeiro;Yannick Ladeiro

  • Two-stage hepatectomy: A planned strategy to treat irresectable liver tumors.

    René Adam;Alexis Laurent;Daniel Azoulay;Denis Castaing

  • Liver Cirrhosis: Intravoxel Incoherent Motion MR Imaging—Pilot Study

    Alain Luciani;Alexandre Vignaud;Madeleine Cavet;Jeanne Tran Van Nhieu

  • High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions

    Jean Charles Nault;Maxime Mallet;Maxime Mallet;Camilla Pilati;Camilla Pilati;Julien Calderaro;Julien Calderaro

  • Resection of nonresectable liver metastases from colorectal cancer after percutaneous portal vein embolization.

    Daniel Azoulay;Denis Castaing;Alloua Smail;René Adam

  • Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases

    D. Zorzi;A. Laurent;T.M. Pawlik;G.Y. Lauwers

  • Controlling Tumor Growth by Modulating Endogenous Production of Reactive Oxygen Species

    Alexis Laurent;Carole Nicco;Christiane Chéreau;Claire Goulvestre

  • Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

    Jean-Charles Nault;Shalini Datta;Sandrine Imbeaud;Andrea Franconi

  • The learning curve in laparoscopic liver resection: improved feasibility and reproducibility.

    Luca Vigano;Alexis Laurent;Claude Tayar;Mariano Tomatis

  • Programmed death ligand 1 expression in hepatocellular carcinoma: Relationship With clinical and pathological features.

    Julien Calderaro;Julien Calderaro;Benoît Rousseau;Benoît Rousseau;Giuliana Amaddeo;Giuliana Amaddeo;Marion Mercey

  • Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo.

    Jérôme Alexandre;Frédéric Batteux;Carole Nicco;Christiane Chéreau

  • Laparoscopic versus open left lateral hepatic lobectomy: a case-control study.

    Mickael Lesurtel;Daniel Cherqui;Alexis Laurent;Claude Tayar

  • Laparoscopic major hepatectomy: an evolution in standard of care.

    Ibrahim Dagher;Nicholas O'Rourke;David Geller;Daniel Cherqui

  • Sarcopenia Impacts on Short- and Long-term Results of Hepatectomy for Hepatocellular Carcinoma.

    Thibault Voron;Lambros Tselikas;Daniel Pietrasz;Frederic Pigneur

  • Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation

    Jean-Charles Nault;Jean-Charles Nault;Gabrielle Couchy;Charles Balabaud;Guillaume Morcrette

  • Laparoscopic Liver Resection for Peripheral Hepatocellular Carcinoma in Patients With Chronic Liver Disease Midterm Results and Perspectives

    Daniel Cherqui;Alexis Laurent;Claude Tayar;Stephen Chang

  • Laparoscopic liver resection for subcapsular hepatocellular carcinoma complicating chronic liver disease.

    Alexis Laurent;Daniel Cherqui;Mickael Lesurtel;Francesco Brunetti

  • A Hepatocellular Carcinoma 5-Gene Score Associated With Survival of Patients After Liver Resection

    Jean–Charles Nault;Jean–Charles Nault;Aurélien De Reyniès;Augusto Villanueva;Augusto Villanueva;Julien Calderaro;Julien Calderaro

Frequent Co-Authors

Daniel Cherqui
Daniel Cherqui Grenoble Alpes University
Daniel Azoulay
Daniel Azoulay Sheba Medical Center
Jessica Zucman-Rossi
Jessica Zucman-Rossi Université Paris Cité
Paulette Bioulac-Sage
Paulette Bioulac-Sage University of Bordeaux
René Adam
René Adam University of Paris-Saclay
Olivier Soubrane
Olivier Soubrane Beaujon Hospital
Frédéric Batteux
Frédéric Batteux Université Paris Cité
Josep M. Llovet
Josep M. Llovet University of Barcelona
Jacques Belghiti
Jacques Belghiti Beaujon Hospital
Valérie Paradis
Valérie Paradis Université Paris Cité

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