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D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
13681
World Ranking
15454
National Ranking
6450

Overview

Giuseppe Astarita is affiliated with Georgetown University in the United States and conducts research primarily in the field of Medicine. Their work spans several specialized subfields, including Neurology, Physiology, Molecular Biology, Spectroscopy, and Cell Biology.

The topics addressed in Giuseppe Astarita's research include:

  • Parkinson's Disease Mechanisms and Treatments
  • Lysosomal Storage Disorders Research
  • Amyotrophic Lateral Sclerosis Research
  • Metabolomics and Mass Spectrometry Studies
  • Cellular transport and secretion
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms

Among the frequent co-authors in their publications are Sonnet S. Davis, Gilbert Di Paolo, Hoang N. Nguyen, Akhil Bhalla, and Junhua Wang.

Giuseppe Astarita has published in a variety of scientific venues, notably including:

  • International Journal of Molecular Sciences
  • Methods in molecular biology
  • Molecular Genetics and Metabolism
  • Science Translational Medicine
  • Cell

The following list highlights some recent papers authored by Giuseppe Astarita along with their publication year and venue:

  • "TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge", 2020, Neuron
  • "Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia", 2020, Nature Neuroscience
  • "Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson's disease", 2022, Science Translational Medicine
  • "Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic", 2021, Cell
  • "Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice", 2020, Science Translational Medicine

Best Publications

  • Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

    Frank H Yu;Massimo Mantegazza;Ruth E Westenbroek;Carol A Robbins

  • Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

    Yasukazu Nakahata;Saurabh Sahar;Giuseppe Astarita;Milota Kaluzova

  • The Nuclear Receptor Peroxisome Proliferator-Activated Receptor-α Mediates the Anti-Inflammatory Actions of Palmitoylethanolamide

    Jesse Lo Verme;Jin Fu;Giuseppe Astarita;Giovanna La Rana

  • PER2 controls lipid metabolism by direct regulation of PPARγ

    Benedetto Grimaldi;Marina Maria Bellet;Sayako Katada;Giuseppe Astarita

  • TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.

    Alicia A. Nugent;Karin Lin;Bettina van Lengerich;Steve Lianoglou

  • The Lipid Messenger OEA Links Dietary Fat Intake to Satiety

    Gary J. Schwartz;Jin Fu;Giuseppe Astarita;Xiaosong Li

  • A neuroscientist's guide to lipidomics

    Daniele Piomelli;Daniele Piomelli;Giuseppe Astarita;Rao Rapaka

  • Ion mobility derived collision cross sections to support metabolomics applications.

    Giuseppe Paglia;Jonathan P. Williams;Lochana Menikarachchi;J. Will Thompson

  • Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification.

    Giuseppe Paglia;Peggi Angel;Jonathan P. Williams;Keith Richardson

  • FOOD INTAKE REGULATES OLEOYLETHANOLAMIDE FORMATION AND DEGRADATION IN THE PROXIMAL SMALL INTESTINE

    Jin Fu;Giuseppe Astarita;Silvana Gaetani;Janet Kim

  • Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus.

    Judit K Makara;Marco Mor;Darren Fegley;Szilárd I Szabó

  • Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation

    Carlos Solorzano;Chenggang Zhu;Natalia Battista;Giuseppe Astarita

  • Metabolomics and lipidomics using traveling-wave ion mobility mass spectrometry.

    Giuseppe Paglia;Giuseppe Astarita

  • Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease

    Giuseppe Astarita;Kwang-Mook Jung;Nicole C. Berchtold;Vinh Q. Nguyen

  • Endocannabinoid signal in the gut controls dietary fat intake

    Nicholas V. DiPatrizio;Giuseppe Astarita;Giuseppe Astarita;Gary Schwartz;Xiaosong Li

  • A key role for diacylglycerol lipase-α in metabotropic glutamate receptor-dependent endocannabinoid mobilization

    Kwang-Mook Jung;Giuseppe Astarita;Chenggang Zhu;Matthew Wallace

  • Applications of ion-mobility mass spectrometry for lipid analysis

    Giuseppe Paglia;Michal Kliman;Emmanuelle Claude;Scott Geromanos

  • Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia.

    Benjamin J Andreone;Laralynne Przybyla;Ceyda Llapashtica;Anil Rana

  • Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids.

    Giuseppe Astarita;Giuseppe Astarita;Alexandra C. Kendall;Edward A. Dennis;Anna Nicolaou

  • Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease

    Giuseppe Astarita;Giuseppe Astarita;Kwang-Mook Jung;Vitaly Vasilevko;Nicholas V. DiPatrizio

Frequent Co-Authors

Daniele Piomelli
Daniele Piomelli University of California, Irvine
Gilbert Di Paolo
Gilbert Di Paolo Columbia University Medical Center
Mauro Maccarrone
Mauro Maccarrone University of L'Aquila
Ryan J. Watts
Ryan J. Watts Denali Therapeutics (United States)
Carl W. Cotman
Carl W. Cotman University of California, Irvine
Gino Roberto Corazza
Gino Roberto Corazza University of Pavia
Giorgio Tarzia
Giorgio Tarzia University of Urbino
Marco Mor
Marco Mor University of Parma
Elizabeth Head
Elizabeth Head University of California, Irvine

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