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D-Index & Metrics

Molecular Biology

D-Index
55
Citations
8572
World Ranking
2290
National Ranking
1127

Overview

Gary L. Griffiths is affiliated with the National Institutes of Health in the United States, with a research focus spanning medicine, immunology, and microbiology. Their work encompasses multiple subfields including radiology, nuclear medicine and imaging, pulmonary and respiratory medicine, immunology, molecular biology, and oncology.

The scientist's research topics include radiopharmaceutical chemistry and applications, medical imaging techniques and applications, prostate cancer treatment and research, peptidase inhibition and analysis, mass spectrometry techniques and applications, microbial infections and disease research, and immune response and inflammation.

Recent publications authored or co-authored by Gary L. Griffiths highlight their involvement in medical imaging and biochemical research. These publications include:

  • Translating a radiolabeled imaging agent to the clinic, 2021, Advanced Drug Delivery Reviews
  • Preclinical Imaging of Prostate Cancer, 2023, Seminars in Nuclear Medicine
  • Correction: Inhibition of glutathione peroxidase mediates the collateral sensitivity of multidrug-resistant cells to tiopronin, 2020, Journal of Biological Chemistry
  • Correction: Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission, 2023, PLoS ONE
  • Retraction of "Collateral Sensitivity of Multidrug-Resistant Cells to the Orphan Drug Tiopronin", 2020, Journal of Medicinal Chemistry

The venues in which they have published include the Journal of Biological Chemistry, Advanced Drug Delivery Reviews, Seminars in Nuclear Medicine, PLoS ONE, and the Journal of Medicinal Chemistry.

Frequent co-authors collaborating with Gary L. Griffiths comprise Peter L. Choyke, Andrew S. Goldsborough, Michael M. Gottesman, Liza Lindenberg, and Esther Mena, indicating interdisciplinary and collaborative research efforts.

Best Publications

  • Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol.

    Xuewei Zhu;John S. Owen;Martha D. Wilson;Haitao Li

  • Preparation and use of immunoconjugates comprising a VL-chain glycosylated at the Asn in position 18

    Seregulam V. Govindan;Gary L. Griffiths;Hans J. Hansen;Shui-On Leung

  • The processing and fate of antibodies and their radiolabels bound to the surface of tumor cells in vitro: a comparison of nine radiolabels.

    L. B. Shih;S. R. Thorpe;G. L. Griffiths;H. Diril

  • Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a human multiple myeloma xenograft and in monkeys.

    Puja Sapra;Rhona Stein;Jennifer Pickett;Zhengxing Qu

  • Reduction of the renal uptake of radiolabeled monoclonal antibody fragments by cationic amino acids and their derivatives.

    Thomas M. Behr;Robert M. Sharkey;Malik E. Juweid;Rosalyn D. Blumenthal

  • Internalization and catabolism of radiolabelled antibodies to the MHC class-II invariant chain by B-cell lymphomas.

    Hans J Hansen;Gaik Lin Ong;Habibe Diril;Anita Valdez

  • Use of bi-specific antibodies for pre-targeting diagnosis and therapy

    Hans J. Hansen;Gary L. Griffiths;Shui-On Leung;William J. Mcbride

  • (89)Zr-Oxine Complex PET Cell Imaging in Monitoring Cell-based Therapies.

    Noriko Sato;Haitao Wu;Kingsley O. Asiedu;Lawrence P. Szajek

  • Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors

    Unknown

  • A universal pretargeting system for cancer detection and therapy using bispecific antibody.

    Robert M. Sharkey;William J. McBride;Habibe Karacay;Ken Chang

  • Processing of antibody-radioisotope conjugates after binding to the surface of tumor cells

    M. Jules Mattes;Gary L. Griffiths;Habibe Diril;David M. Goldenberg

  • Cure of SCID Mice Bearing Human B-Lymphoma Xenografts by an Anti-CD74 Antibody-Anthracycline Drug Conjugate

    Gary L Griffiths;M Jules Mattes;Rhona Stein;Serengulam V Govindan

  • Experimental pretargeting studies of cancer with a humanized anti-CEA x murine anti-[In-DTPA] bispecific antibody construct and a (99m)Tc-/(188)Re-labeled peptide.

    H Karacay;W J McBride;G L Griffiths;R M Sharkey

  • 90Y-DOTA-hLL2: An Agent for Radioimmunotherapy of Non-Hodgkin’s Lymphoma

    Gary L. Griffiths;Serengulam V. Govindan;Robert M. Sharkey;Darrell R. Fisher

  • Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates

    David Milton Goldenberg;Gary L. Griffiths;Hans J. Hansen

  • Direct Radiolabeling of Monoclonal Antibodies with Generator-produced Rhenium-188 for Radioimmunotherapy: Labeling and Animal Biodistribution Studies

    Gary L. Griffiths;David M. Goldenberg;Furn F. Knapp;Alvin P. Callahan

  • PRODUCTION AND USE OF NOVEL PEPTIDE-BASED AGENT FOR USE WITH BI-SPECIFIC ANTIBODY

    Hansen Hans J;Griffiths Gary L;Leung Shui-On;Mcbride William J

  • Mitochondrial NADH fluorescence is enhanced by complex I binding.

    Ksenia Blinova;Rodney L. Levine;Emily S. Boja;Gary L. Griffiths

  • Improved Iodine Radiolabels for Monoclonal Antibody Therapy

    Rhona Stein;Serengulam V. Govindan;M. Jules Mattes;Susan Chen

  • Advantage of residualizing radiolabels for an internalizing antibody against the B-cell lymphoma antigen, CD22

    R M Sharkey;T M Behr;M J Mattes;R Stein

Frequent Co-Authors

Hans J. Hansen
Hans J. Hansen Eisai (Japan)
David M. Goldenberg
David M. Goldenberg Immunomedics (United States)
Robert M. Sharkey
Robert M. Sharkey University of Fukui
Peter L. Choyke
Peter L. Choyke National Institutes of Health
Ivan D. Horak
Ivan D. Horak Freie Universität Berlin
Samuel Achilefu
Samuel Achilefu Washington University in St. Louis
Matthew D. Hall
Matthew D. Hall National Institutes of Health
Ronald M. Summers
Ronald M. Summers National Institutes of Health
Chien-Hsing Chang
Chien-Hsing Chang Northwestern University
Hisataka Kobayashi
Hisataka Kobayashi National Institutes of Health

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