World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
39844
World Ranking
2175
National Ranking
1177

Edward H. Koo publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Edward H. Koo sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 239 publications — 64th percentile

64% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Edward H. Koo D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Edward H. Koo sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 92 D-Index — 89th percentile

89% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Edward H. Koo is affiliated with the University of California, San Diego in the United States. Their research focuses on medicine, with significant contributions in biochemistry, genetics, and molecular biology. The main subfields within their work encompass physiology, molecular biology, psychiatry and mental health, cellular and molecular neuroscience, and pharmacology.

The scientist's research primarily addresses topics such as Alzheimer's disease research and treatments, neuroscience and neuropharmacology research, dementia and cognitive impairment research, cholinesterase and neurodegenerative diseases, cellular transport and secretion, multiple myeloma research and treatments, and protein degradation and inhibitors.

Frequent venues for publication include bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, Acta Neuropathologica Communications, Scientific Reports, and Alzheimer's & Dementia.

Notable recent papers include:

  • World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia, 2020, Alzheimer's & Dementia
  • Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer's Disease, 2020, Cell Reports
  • Presymptomatic Increase of an Extracellular RNA in Blood Plasma Associates with the Development of Alzheimer's Disease, 2020, Current Biology
  • Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits, 2021, Acta Neuropathologica Communications
  • SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)-pilot: A feasibility study, 2021, Alzheimer's & Dementia Translational Research & Clinical Interventions

Edward H. Koo has collaborated regularly with several co-authors, including Christopher Chen, Sheue-Houy Tyan, Stefan Kins, Effie Chew, and Christiani Jeyakumar Henry.

In 2015, the scientist was awarded the distinction of Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Amyloid β-peptide is produced by cultured cells during normal metabolism

    C Haass;M G Schlossmacher;M G Schlossmacher;A Y Hung;C Vigo-Pelfrey

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

    Sascha Weggen;Jason L. Eriksen;Pritam Das;Sarah A. Sagi

  • Amyloid Precursor Protein Trafficking, Processing, and Function

    Gopal Thinakaran;Edward H. Koo

  • Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

    Mason A. Israel;Shauna H. Yuan;Cedric Bardy;Sol M. Reyna

  • Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing.

    S. S. Sisodia;E. H. Koo;K. Beyreuther;A. Unterbeck

  • Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

    Christian Haass;Edward H. Koo;Angela Mellon;Albert Y. Hung

  • Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

    Alan H Nagahara;David A Merrill;Giovanni Coppola;Shingo Tsukada

  • Amyloid diseases: abnormal protein aggregation in neurodegeneration.

    Edward H. Koo;Peter T. Lansbury;Jeffery W. Kelly

  • Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

    Edward H. Koo;Sangram S. Sisodia;David R. Archer;Lee J. Martin

  • NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo

    Jason L. Eriksen;Sarah A. Sagi;Tawnya E. Smith;Sascha Weggen

  • Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein

    Sung Hee Baek;Kenneth A. Ohgi;David W. Rose;Edward H. Koo

  • The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

    Lemere Ca;Lopera F;Kosik Ks;Lendon Cl

  • Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture.

    Marcia B. Podlisny;Beth L. Ostaszewski;Sharon L. Squazzo;Edward H. Koo

  • A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor

    Daniel C. Lu;Daniel C. Lu;Shahrooz Rabizadeh;Shahrooz Rabizadeh;Sreeganga Chandra;Rana F. Shayya

  • Mutagenesis Identifies New Signals for β-Amyloid Precursor Protein Endocytosis, Turnover, and the Generation of Secreted Fragments, Including Aβ42

    Ruth G. Perez;Salvador Soriano;Jay D. Hayes;Beth Ostaszewski

  • The amyloid precursor protein: beyond amyloid.

    Hui Zheng;Hui Zheng;Edward H Koo;Edward H Koo

  • Modulation of amyloid β-protein clearance and Alzheimer’s disease susceptibility by the LDL receptor–related protein pathway

    David E. Kang;Claus U. Pietrzik;Larry Baum;Nathalie Chevallier

  • Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift

    Todd E. Golde;Lon S. Schneider;Edward H. Koo

  • Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.

    Marcia B. Podlisny;Martin Citron;Patricia Amarante;Robin Sherrington

Frequent Co-Authors

Todd E. Golde
Todd E. Golde Emory University
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Dale E. Bredesen
Dale E. Bredesen University of California, Los Angeles
Douglas Galasko
Douglas Galasko University of California, San Diego
Bradley T. Hyman
Bradley T. Hyman Harvard University
Peter St George-Hyslop
Peter St George-Hyslop Columbia University
Daniel H. Geschwind
Daniel H. Geschwind University of California, Los Angeles
Philip L. De Jager
Philip L. De Jager Columbia University
Mark H. Tuszynski
Mark H. Tuszynski University of California, San Diego
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami

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