His primary scientific interests are in Virology, Virus, Semliki Forest virus, Viral replication and Immunology. His Virology study often links to related topics such as RNA interference. His Virus research integrates issues from RNA, Molecular biology, Lymphoproliferative disorders and Immune system.
While the research belongs to areas of Semliki Forest virus, he spends his time largely on the problem of Apoptosis, intersecting his research to questions surrounding Viral shedding, Viral transformation, Viral entry and Nuclear transport. John K. Fazakerley studied Arbovirus and Dengue virus that intersect with Gene knockdown, Piwi-interacting RNA and Effector. The concepts of his Alphavirus study are interwoven with issues in RIG-I, Sindbis virus, Gene silencing and Regulation of gene expression.
John K. Fazakerley mostly deals with Virology, Virus, Semliki Forest virus, Alphavirus and Immunology. His research on Virology frequently links to adjacent areas such as Immune system. His studies in Virus integrate themes in fields like Apoptosis, Antibody and Central nervous system, Neuroglia.
His research investigates the connection between Semliki Forest virus and topics such as Molecular biology that intersect with issues in Bunyamwera virus, Gene expression and RNA. His Alphavirus study integrates concerns from other disciplines, such as Viremia, Togaviridae, Chikungunya, Sindbis virus and Subgenomic mRNA. His study in the fields of Innate immune system, Immunity, T cell and Autoimmunity under the domain of Immunology overlaps with other disciplines such as Microglia.
John K. Fazakerley spends much of his time researching Virology, Virus, Alphavirus, Arbovirus and Semliki Forest virus. His Virology research is multidisciplinary, incorporating perspectives in RNA interference and Innate immune system. His research on Virus concerns the broader Immunology.
His studies deal with areas such as Chikungunya and Togaviridae, Antibody as well as Alphavirus. His study in the field of Arbovirus Infections is also linked to topics like Aedes aegypti. His work carried out in the field of Semliki Forest virus brings together such families of science as Sindbis virus and Virulence.
His primary areas of investigation include Virology, Virus, RNA interference, Arbovirus and Flavivirus. His work deals with themes such as Semliki Forest virus and Immunology, which intersect with Virology. His Flavivirus research includes elements of Tick-borne encephalitis virus, Ixodes, Ixodes ricinus, Tick and Ixodes scapularis.
His research in Alphavirus intersects with topics in Subgenomic mRNA, Viral Interference, Argonaute and Langat virus. His biological study spans a wide range of topics, including Interferon, IRF7, Herpes simplex virus and Neurotropic virus. His work deals with themes such as Gene knockdown, Zika virus, Piwi-interacting RNA, Yellow fever and Effector, which intersect with Dengue virus.
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Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis
Anne Bridgen;Friedemann Weber;John K. Fazakerley;Richard M. Elliott.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Bunyamwera Bunyavirus Nonstructural Protein NSs Counteracts the Induction of Alpha/Beta Interferon
Friedemann Weber;Anne Bridgen;John K. Fazakerley;Hein Streitenfeld.
Journal of Virology (2002)
Lymphoproliferative disease in mice infected with murine gammaherpesvirus 68.
N P Sunil-Chandra;J Arno;John Fazakerley;Anthony Nash.
American Journal of Pathology (1994)
Knockdown of piRNA pathway proteins results in enhanced Semliki Forest virus production in mosquito cells
Esther Schnettler;Esther Schnettler;Claire L. Donald;Claire L. Donald;Stacey Human;Stacey Human;Mick Watson.
Journal of General Virology (2013)
Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection
Marieke Pingen;Steven R. Bryden;Steven R. Bryden;Emilie Pondeville;Esther Schnettler.
Antiviral RNA Interference Responses Induced by Semliki Forest Virus Infection of Mosquito Cells: Characterization, Origin, and Frequency-Dependent Functions of Virus-Derived Small Interfering RNAs
Ricky W. C. Siu;Rennos Fragkoudis;Peter Simmonds;Claire L. Donald.
Journal of Virology (2011)
Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.
David Hallengärd;Maria Kakoulidou;Aleksei Lulla;Beate M. Kümmerer.
Journal of Virology (2014)
Advances in dissecting mosquito innate immune responses to arbovirus infection.
Rennos Fragkoudis;Ghassem Attarzadeh-Yazdi;Anthony A. Nash;John K. Fazakerley.
Journal of General Virology (2009)
Replication of the A7(74) strain of Semliki Forest virus is restricted in neurons
John K. Fazakerley;Snehlata Pathak;Martina Scallan;Sandra Amor.
The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system.
John K. Fazakerley;Suezanne E. Parker;Floyd Bloom;Michael J. Buchmeier.
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