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Overview

Edward Abraham is affiliated with Dragonfly Data Science in New Zealand. Their research primarily spans the field of Medicine, with a focus on subfields including Pulmonary and Respiratory Medicine, Molecular Biology, Oncology, Epidemiology, and Biotechnology.

Their research topics cover a range of biomedical and clinical interests, notably:

  • Cholesterol and Lipid Metabolism
  • Phagocytosis and Immune Regulation
  • Sphingolipid Metabolism and Signaling
  • HER2/EGFR in Cancer Research
  • Breast Cancer Treatment Studies
  • Advanced Breast Cancer Therapies
  • Cystic Fibrosis Research Advances

Edward Abraham has authored several papers in reputable scientific journals. Some recent publications include:

  • "Cholesterol-25-hydroxylase promotes efferocytosis and resolution of lung inflammation," 2020, published in JCI Insight
  • "Response-guided neoadjuvant sacituzumab govitecan for localized triple-negative breast cancer: results from the NeoSTAR trial," 2023, published in Annals of Oncology
  • "Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2," 2021, published in Purinergic Signalling
  • "Moving Forward With Refinement of Definitions for Sepsis*," 2021, published in Critical Care Medicine
  • "1093P Neoadjuvant (NeoAd) intratumoral (IT) TAVO-EP (plasmid IL-12 electro gene transfer) in combination with nivolumab (NIVO) for patients (pts) with operable locoregionally advanced melanoma," 2023, published in Annals of Oncology

Frequent co-authors of Edward Abraham include:

  • D. Varghese
  • Jennifer H. Madenspacher
  • Eric D. Morrell
  • Kymberly M. Gowdy
  • Jeffrey G. McDonald

Their work has been published predominantly in venues such as Annals of Oncology, UNC Libraries, JCI Insight, Purinergic Signalling, and Critical Care Medicine. Annals of Oncology and UNC Libraries are notable for multiple publications by this author.

Best Publications

  • 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

    Mitchell M. Levy;Mitchell P. Fink;John C. Marshall;Edward Abraham

  • HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

    Haichao Wang;Ona Bloom;Minghuang Zhang;Jaideep M. Vishnubhakat

  • The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States.

    Howard L. Corwin;Andrew Gettinger;Ronald G. Pearl;Mitchell P. Fink

  • Treatment of Septic Shock with the Tumor Necrosis Factor Receptor:Fc Fusion Protein

    Charles J. Fisher;Jan M. Agosti;Steven M. Opal;Stephen F. Lowry

  • High mobility group box 1 protein interacts with multiple Toll-like receptors

    Jong Sung Park;Fabia Gamboni-Robertson;Qianbin He;Daiva Svetkauskaite

  • Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial.

    Edward Abraham;Konrad Reinhart;Steven Opal;Ignace Demeyer

  • Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial

    E Abraham;R Wunderink;H Silverman;T M Perl

  • Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group

    Steven M. Opal;Charles J. Fisher;Jean-Francois A. Dhainaut;Jean-Louis Vincent

  • HMG-1 as a mediator of acute lung inflammation.

    Edward Abraham;John Arcaroli;Aaron Carmody;Haichao Wang

  • miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

    Gang Liu;Arnaud Friggeri;Yanping Yang;Jadranka Milosevic

  • Transfusion-related acute lung injury : Definition and review

    Pearl Toy;Mark A. Popovsky;Edward Abraham;Daniel R. Ambruso

  • Double-blind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock

    Edward Abraham;Antonio Anzueto;Guillermo Gutierrez;Sidney Tessler

  • Urine IL-18 Is an Early Diagnostic Marker for Acute Kidney Injury and Predicts Mortality in the Intensive Care Unit

    Chirag R. Parikh;Edward Abraham;Marek Ancukiewicz;Charles L. Edelstein

  • Mechanisms of sepsis-induced organ dysfunction

    Edward Abraham;Mervyn Singer

  • Activation of gene expression in human neutrophils by high mobility group box 1 protein

    Jong Sung Park;John Arcaroli;Ho Kee Yum;Huan Yang

  • HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines

    Yonggang Sha;Jaroslaw Zmijewski;Zhiwei Xu;Edward Abraham

  • p55 Tumor Necrosis Factor Receptor Fusion Protein in the Treatment of Patients With Severe Sepsis and Septic Shock: A Randomized Controlled Multicenter Trial

    Edward Abraham;Michel P. Glauser;Thomas Butler;Jorge Garbino

  • Severe Sepsis and Septic Shock: Review of the Literature and Emergency Department Management Guidelines

    H. Bryant Nguyen;Emanuel P. Rivers;Fredrick M. Abrahamian;Gregory J. Moran

  • miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

    Gang Liu;Arnaud Friggeri;Yanping Yang;Young-Jun Park

  • The multidrug resistance (mdr1) gene product functions as an ATP channel.

    Edward H. Abraham;Adriana G. Prat;Leo Gerweck;Tara Seneveratne

Frequent Co-Authors

Charles G. Fisher
Charles G. Fisher University of British Columbia
William C. Shoemaker
William C. Shoemaker University of Southern California
Steven M. Opal
Steven M. Opal Brown University
Jean Louis Vincent
Jean Louis Vincent Université Libre de Bruxelles
Mitchell P. Fink
Mitchell P. Fink University of California, Los Angeles
Gordon R. Bernard
Gordon R. Bernard Vanderbilt University Medical Center
Joel S. Finkelstein
Joel S. Finkelstein Sunnybrook Health Science Centre
William MacNee
William MacNee University of Edinburgh
John E. Repine
John E. Repine University of Colorado Denver
Stephen F. Lowry
Stephen F. Lowry Rutgers, The State University of New Jersey

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