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D-Index & Metrics

Biology and Biochemistry

D-Index
103
Citations
62560
World Ranking
1288
National Ranking
755

Overview

Edward Abraham is affiliated with the University of Miami in the United States and has contributed extensively to the field of medicine, with a focus on pulmonary and respiratory medicine, molecular biology, oncology, epidemiology, and biotechnology. Their research spans key areas such as cholesterol and lipid metabolism, phagocytosis and immune regulation, sphingolipid metabolism and signaling, HER2/EGFR in cancer research, breast cancer treatment studies, advanced breast cancer therapies, and cystic fibrosis research advances.

Major research topics addressed by Edward Abraham include:

  • Cholesterol and Lipid Metabolism
  • Phagocytosis and Immune Regulation
  • Sphingolipid Metabolism and Signaling
  • HER2/EGFR in Cancer Research
  • Breast Cancer Treatment Studies
  • Advanced Breast Cancer Therapies
  • Cystic Fibrosis Research Advances

Frequent coauthors collaborating with Edward Abraham have included:

  • D. Varghese
  • Jennifer H. Madenspacher
  • Eric D. Morrell
  • Kymberly M. Gowdy
  • Jeffrey G. McDonald

Among the notable publication venues where Edward Abraham has appeared are:

  • Annals of Oncology
  • UNC Libraries
  • JCI Insight
  • Purinergic Signalling
  • Critical Care Medicine

Selected recent papers authored or coauthored by Edward Abraham include:

  • "Cholesterol-25-hydroxylase promotes efferocytosis and resolution of lung inflammation", 2020, JCI Insight
  • "Response-guided neoadjuvant sacituzumab govitecan for localized triple-negative breast cancer: results from the NeoSTAR trial", 2023, Annals of Oncology
  • "Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2", 2021, Purinergic Signalling
  • "Moving Forward With Refinement of Definitions for Sepsis*", 2021, Critical Care Medicine
  • "1093P Neoadjuvant (NeoAd) intratumoral (IT) TAVO-EP (plasmid IL-12 electro gene transfer) in combination with nivolumab (NIVO) for patients (pts) with operable locoregionally advanced melanoma", 2023, Annals of Oncology

Their work reflects a multidisciplinary approach integrating clinical studies and molecular insights in medicine, addressing complex diseases including breast cancer, lung inflammation, sepsis, melanoma, and COVID-19. Through collaboration with other researchers and publication in diverse high-impact venues, Edward Abraham contributes to advancing understanding and potential therapies across several medical specialties.

Best Publications

  • 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

    Mitchell M. Levy;Mitchell P. Fink;John C. Marshall;Edward Abraham

  • HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

    Haichao Wang;Ona Bloom;Minghuang Zhang;Jaideep M. Vishnubhakat

  • Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein.

    Jong Sung Park;Daiva Svetkauskaite;Qianbin He;Jae-Yeol Kim

  • High mobility group box 1 protein interacts with multiple Toll-like receptors

    Jong Sung Park;Fabia Gamboni-Robertson;Qianbin He;Daiva Svetkauskaite

  • Neutrophils and acute lung injury.

    Edward Abraham

  • Drotrecogin Alfa (Activated) for Adults with Severe Sepsis and a Low Risk of Death

    Edward Abraham;Pierre-François Laterre;Rekha Garg;Howard Levy

  • HMG-1 as a mediator of acute lung inflammation.

    Edward Abraham;John Arcaroli;Aaron Carmody;Haichao Wang

  • miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

    Gang Liu;Arnaud Friggeri;Yanping Yang;Jadranka Milosevic

  • Urine IL-18 Is an Early Diagnostic Marker for Acute Kidney Injury and Predicts Mortality in the Intensive Care Unit

    Chirag R. Parikh;Edward Abraham;Marek Ancukiewicz;Charles L. Edelstein

  • Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B.

    Karim Asehnoune;Derek Strassheim;Sanchayita Mitra;Jae Yeol Kim

  • Mechanisms of sepsis-induced organ dysfunction

    Edward Abraham;Mervyn Singer

  • Activation of gene expression in human neutrophils by high mobility group box 1 protein

    Jong Sung Park;John Arcaroli;Ho Kee Yum;Huan Yang

  • Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury

    Edward Abraham;Aaron Carmody;Robert Shenkar;John Arcaroli

  • HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines

    Yonggang Sha;Jaroslaw Zmijewski;Zhiwei Xu;Edward Abraham

  • p55 Tumor Necrosis Factor Receptor Fusion Protein in the Treatment of Patients With Severe Sepsis and Septic Shock: A Randomized Controlled Multicenter Trial

    Edward Abraham;Michel P. Glauser;Thomas Butler;Jorge Garbino

  • miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

    Gang Liu;Arnaud Friggeri;Yanping Yang;Young-Jun Park

  • The multidrug resistance (mdr1) gene product functions as an ATP channel.

    Edward H. Abraham;Adriana G. Prat;Leo Gerweck;Tara Seneveratne

  • Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation.

    Edward Abraham;Michael A. Matthay;Charles A. Dinarello;Jean-Louis Vincent

  • Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase.

    Jaroslaw W. Zmijewski;Sami Banerjee;Hongbeom Bae;Arnaud Friggeri

  • The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.

    I L Reisin;A G Prat;E H Abraham;J F Amara

Frequent Co-Authors

Jaroslaw W. Zmijewski
Jaroslaw W. Zmijewski University of Alabama at Birmingham
Gang Liu
Gang Liu University of Alabama at Birmingham
Victor J. Thannickal
Victor J. Thannickal Tulane University
Jean Louis Vincent
Jean Louis Vincent Université Libre de Bruxelles
Steven M. Opal
Steven M. Opal Brown University
Bayard L. Powell
Bayard L. Powell Wake Forest University
Jerry A. Nick
Jerry A. Nick National Jewish Health
Michel P. Glauser
Michel P. Glauser University Hospital of Lausanne
Kevin J. Tracey
Kevin J. Tracey Feinstein Institute for Medical Research
Deborah J. Cook
Deborah J. Cook McMaster University

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