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Earl D. Silverman

Earl D. Silverman

D-Index & Metrics

Medicine

D-Index
96
Citations
28681
World Ranking
9799
National Ranking
393

Overview

Earl D. Silverman is affiliated with the University of Toronto in Canada and has made significant contributions to the field of Medicine, particularly focusing on Rheumatology and Immunology.

Their research spans several specialized subfields, including Rheumatology, Immunology, Hematology, Speech and Hearing, and Surgery. The scientist's publication record highlights a concentration on systemic autoimmune and inflammatory disorders, with notable work related to systemic lupus erythematosus and immune cell function.

Main topics of their research include:

  • Systemic Lupus Erythematosus Research
  • Autoimmune and Inflammatory Disorders Research
  • Adolescent and Pediatric Healthcare
  • Immune Cell Function and Interaction
  • Kawasaki Disease and Coronary Complications
  • Immunodeficiency and Autoimmune Disorders
  • Diabetes and associated disorders

Silverman has published extensively, with a selection of recent papers illustrating the scope of their work:

  • "Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus," 2020, The Journal of Rheumatology
  • "Efficacy and Safety of Tocilizumab for Polyarticular-Course Juvenile Idiopathic Arthritis in the Open-Label Two-Year Extension of a Phase III Trial," 2020, Arthritis & Rheumatology
  • "Predicting Macrophage Activation Syndrome in Childhood-onset Systemic Lupus Erythematosus Patients at Diagnosis," 2020, The Journal of Rheumatology
  • "Maternal Anti-Ro Antibody Titers Obtained With Commercially Available Immunoassays Are Strongly Associated With Immune-Mediated Fetal Heart Disease," 2023, Arthritis & Rheumatology
  • "Effects of Transplacental Dexamethasone Therapy on Fetal Immune-Mediated Complete Heart Block," 2021, Fetal Diagnosis and Therapy

Their research has been featured predominantly in a few key venues:

  • The Journal of Rheumatology (21 publications)
  • Lara D. Veeken (5 publications)
  • Arthritis & Rheumatology (3 publications)
  • Arthritis Care & Research (2 publications)
  • Abstracts (2 publications)

Among Silverman's frequent collaborators are several researchers with whom the scientist has co-authored multiple papers. These include Linda T. Hiraki, Andrea Knight, Deborah M. Levy, Daniela Domínguez, and Lawrence Ng. The breadth of coauthorship indicates active collaboration within their research community.

Best Publications

  • Etanercept in Children with Polyarticular Juvenile Rheumatoid Arthritis

    Daniel J. Lovell;Edward H. Giannini;Andreas Reiff;Gail D. Cawkwell

  • Difference in disease features between childhood‐onset and adult‐onset systemic lupus erythematosus

    Hermine I. Brunner;Dafna D. Gladman;Dominique Ibañez;Murray D. Urowitz

  • Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test.

    Anath C Lionel;Gregory Costain;Nasim Monfared;Susan Walker

  • A randomized, placebo‐controlled trial of infliximab plus methotrexate for the treatment of polyarticular‐course juvenile rheumatoid arthritis

    Nicolino Ruperto;Daniel J. Lovell;Ruben Cuttica;Nick Wilkinson

  • Clinical and laboratory characteristics and long-term outcome of pediatric systemic lupus erythematosus: a longitudinal study.

    Linda T. Hiraki;Susanne M. Benseler;Pascal N. Tyrrell;Diane Hebert

  • Outcome of children with fetal, neonatal or childhood diagnosis of isolated congenital atrioventricular block: A single institution's experience of 30 years

    Edgard Jaeggi;Edgard Jaeggi;Robert M Hamilton;Earl D Silverman;Samuel Antonio Zamora

  • Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    Jenny C. Taylor;Jenny C. Taylor;Hilary C. Martin;Stefano Lise;John Broxholme

  • Transplacental fetal treatment improves the outcome of prenatally diagnosed complete atrioventricular block without structural heart disease

    Edgar T. Jaeggi;Jean-Claude Fouron;Earl D. Silverman;Greg Ryan

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • Prevalence and burden of pediatric-onset systemic lupus erythematosus.

    Sylvia Kamphuis;Earl D. Silverman

  • Risk factors for damage in childhood-onset systemic lupus erythematosus: cumulative disease activity and medication use predict disease damage.

    Hermine I. Brunner;Earl D. Silverman;Theresa To;Claire Bombardier

  • Leflunomide or methotrexate for juvenile rheumatoid arthritis.

    Earl Silverman;Richard Mouy;Lynn Spiegel;Lawrence K. Jung

  • Epidemiology of Juvenile Idiopathic Arthritis in a Multiethnic Cohort Ethnicity as a Risk Factor

    R. K. Saurenmann;J. B. Rose;P. Tyrrell;B. M. Feldman

  • Prevalence, risk factors, and outcome of uveitis in juvenile idiopathic arthritis: a long-term followup study

    R. K. Saurenmann;A. V. Levin;B. M. Feldman;J. B. Rose

  • The importance of the level of maternal anti-Ro/SSA antibodies as a prognostic marker of the development of cardiac neonatal lupus erythematosus a prospective study of 186 antibody-exposed fetuses and infants.

    Edgar Jaeggi;Carl Laskin;Robert Hamilton;John Kingdom

  • Sensitivity of the Systemic Lupus Erythematosus Disease Activity Index, British Isles Lupus Assessment Group Index, and Systemic Lupus Activity Measure in the evaluation of clinical change in childhood-onset systemic lupus erythematosus.

    Hermine I. Brunner;Brian M. Feldman;C. Bombardier;Earl D. Silverman

  • Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial

    Hermine I Brunner;Nicolino Ruperto;Zbigniew Zuber;Caroline Keane

  • The role of antimalarial agents in the treatment of SLE and lupus nephritis

    Senq J. Lee;Earl Silverman;Joanne M. Bargman

  • Incidence and spectrum of neonatal lupus erythematosus: a prospective study of infants born to mothers with anti-Ro autoantibodies.

    Rolando Cimaz;Dawn L. Spence;Lisa Hornberger;Earl D. Silverman

  • Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

    Chaim O. Jacob;Jiankun Zhu;Don L. Armstrong;Don L. Armstrong;Mei Yan

Frequent Co-Authors

Ronald M. Laxer
Ronald M. Laxer University of Toronto
Brian M. Feldman
Brian M. Feldman University of Toronto
Dafna D. Gladman
Dafna D. Gladman Toronto Western Hospital
Janet E. Pope
Janet E. Pope University of Western Ontario
Brian W. McCrindle
Brian W. McCrindle University of Toronto
Paul R. Fortin
Paul R. Fortin Université Laval
Alberto Martini
Alberto Martini University of Genoa
John B. Harley
John B. Harley United States Department of Veterans Affairs
Ann E. Clarke
Ann E. Clarke University of Calgary
Gideon Koren
Gideon Koren Brown University

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