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Molecular Biology

D-Index
43
Citations
9711
World Ranking
2959
National Ranking
116

Overview

Didier Trouche is affiliated with the Federal University of Toulouse Midi-Pyrénées in France. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions to Molecular Biology, Cancer Research, Oncology, Genetics, and Ecology.

The scientist's recent publications cover various aspects of molecular and cellular mechanisms, including the regulation of gene expression and DNA repair. Notable papers include:

  • RNA polymerase II speed: a key player in controlling and adapting transcriptome composition, 2021, The EMBO Journal
  • Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation, 2020, eLife
  • KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance, 2021, Biology Open
  • JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage, 2020, PLoS Genetics
  • Cytolethal Distending Toxin Promotes Replicative Stress Leading to Genetic Instability Transmitted to Daughter Cells, 2021, Frontiers in Cell and Developmental Biology

Frequent publication venues for Didier Trouche's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular and Cellular Biology
  • The EMBO Journal
  • eLife
  • Biology Open

Their research topics encompass:

  • Epigenetics and DNA Methylation
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer
  • CRISPR and Genetic Engineering
  • DNA Repair Mechanisms
  • Circular RNAs in diseases
  • Cancer-related molecular mechanisms research

Frequent coauthors collaborating with Didier Trouche include Estelle Nicolas, Lisa Muniz, Julien Ouvrard, Marion Aguirrebengoa, and Virginie Jouffret.

Best Publications

  • Retinoblastoma protein represses transcription by recruiting a histone deacetylase

    L. Magnaghi-Jaulin;R. Groisman;I. Naguibneva;P. Robin

  • Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein.

    K Martin;D Trouche;C Hagemeier;T S Sørensen

  • High‐resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

    Jason S Iacovoni;Pierre Caron;Pierre Caron;Imen Lassadi;Imen Lassadi;Estelle Nicolas;Estelle Nicolas

  • Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1α

    Christian Muchardt;Marie Guillemé;Jacob‐S Seeler;Didier Trouche

  • Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A

    S. Ait-Si-Ali;S. Ramirez;F.-X. Barre;F. Dkhissi

  • RB and hbrm cooperate to repress the activation functions of E2F1

    Didier Trouche;Catherine Le Chalony;Christian Muchardt;Moshe Yaniv

  • The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

    Roger Ferreira;Laura Magnaghi-Jaulin;Philippe Robin;Annick Harel-Bellan

  • Regulating histone acetyltransferases and deacetylases

    Gaëlle Legube;Didier Trouche

  • Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase.

    Laurence Vandel;Estelle Nicolas;Olivier Vaute;Roger Ferreira

  • Repression of RNA polymerase III transcription by the retinoblastoma protein

    Robert J. White;Didier Trouche;Didier Trouche;Klaus Martin;Stephen P. Jackson

  • Control of CBP co-activating activity by arginine methylation

    Martine Chevillard-Briet;Didier Trouche;Laurence Vandel

  • CENP-A Is Required for Accurate Chromosome Segregation and Sustained Kinetochore Association of BubR1

    Vinciane Régnier;Paola Vagnarelli;Tatsuo Fukagawa;Tatiana Zerjal

  • Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases

    Olivier Vaute;Estelle Nicolas;Laurence Vandel;Didier Trouche

  • Role of the Histone Acetyl Transferase Tip60 in the p53 Pathway

    Gaëlle Legube;Laetitia K. Linares;Sandrine Tyteca;Cécile Caron

  • CBP/p300 histone acetyl-transferase activity is important for the G1/S transition

    Slimane Ait-Si-Ali;Anna Polesskaya;Stéphanie Filleur;Roger Ferreira

  • The CBP Co-Activator Stimulates E2F1/DP1 Activity

    Didier Trouche;Alistair Cook;Tony Kouzarides

  • Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation.

    Gaëlle Legube;Laetitia K. Linares;Claudie Lemercier;Martin Scheffner

  • Phosphorylation by p44 MAP Kinase/ERK1 Stimulates CBP Histone Acetyl Transferase Activity in Vitro

    Slimane Ait-Si-Ali;Didier Carlisi;Sandra Ramirez;Lia-Cristina Upegui-Gonzalez

  • RbAp48 belongs to the histone deacetylase complex that associates with the retinoblastoma protein.

    Estelle Nicolas;Violette Morales;Laura Magnaghi-Jaulin;Annick Harel-Bellan

  • Physical Interaction between the Mitogen-responsive Serum Response Factor and Myogenic Basic-Helix-Loop-Helix Proteins

    Regina Groisman;Hiroshi Masutani;Marie-Pierre Leibovitch;Philippe Robin

Frequent Co-Authors

Annick Harel-Bellan
Annick Harel-Bellan Centre national de la recherche scientifique, CNRS
Tony Kouzarides
Tony Kouzarides University of Cambridge
Jacques Côté
Jacques Côté Université Laval
Saadi Khochbin
Saadi Khochbin Grenoble Alpes University
Moshe Yaniv
Moshe Yaniv Institut Pasteur
Alain Jauneau
Alain Jauneau Paul Sabatier University
Martin Scheffner
Martin Scheffner University of Konstanz
Marcel Méchali
Marcel Méchali Centre national de la recherche scientifique, CNRS
Philippe Pasero
Philippe Pasero Centre national de la recherche scientifique, CNRS
Pierre-Antoine Gourraud
Pierre-Antoine Gourraud University of Nantes

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