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Biology and Biochemistry

D-Index
59
Citations
13694
World Ranking
12447
National Ranking
961

Overview

Clare E. Futter is affiliated with University College London in the United Kingdom. Their research spans multiple fields, primarily focusing on biochemistry, genetics, and molecular biology, as well as medicine. This work is further specialized in molecular biology, ophthalmology, and cell biology, extending to areas such as epidemiology and physiology.

The scientist's research topics prominently include retinal development and disorders, retinal diseases and treatments, cellular transport and secretion, mitochondrial function and pathology, autophagy in disease and therapy, lysosomal storage disorders research, and investigations related to SARS-CoV-2 and COVID-19.

Recent published papers by Clare E. Futter include:

  • Current methods to analyze lysosome morphology, positioning, motility and function (2022, Traffic)
  • Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1 (2020, Proceedings of the National Academy of Sciences)
  • Ultrastructural insight into SARS-CoV-2 entry and budding in human airway epithelium (2022, Nature Communications)
  • Chronically shortened rod outer segments accompany photoreceptor cell death in Choroideremia (2020, PLoS ONE)
  • Membrane trafficking in the retinal pigment epithelium at a glance (2020, Journal of Cell Science)

Frequent co-authors in their research collaborations include:

  • Thomas Burgoyne
  • Miguel C. Seabra
  • Otília V. Vieira
  • Cristina Escrevente
  • Michael J. Hall

Clare E. Futter has published multiple articles in several recurring venues such as bioRxiv (Cold Spring Harbor Laboratory), Traffic, PLoS ONE, Journal of Cell Science, and Investigative Ophthalmology & Visual Science.

Best Publications

  • Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

    Omar S. Qureshi;Yong Zheng;Kyoko Nakamura;Kesley Attridge

  • EGF receptor trafficking: consequences for signaling and cancer.

    Alejandra Tomas;Clare E. Futter;Emily R. Eden

  • Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes.

    C E Futter;A Pearse;L J Hewlett;C R Hopkins

  • Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal growth factor receptor interaction.

    Emily R. Eden;Ian J. White;Anna Tsapara;Clare E. Futter

  • EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation

    Ian J White;Lorna M Bailey;Minoo Razi Aghakhani;Stephen E Moss

  • Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation.

    M. Razi;C. E. Futter

  • The MAP kinase kinase kinase MLK2 co‐localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

    Koh‐ichi Nagata;Axel Puls;Clare Futter;Pontus Aspenstrom

  • Annexin I is phosphorylated in the multivesicular body during the processing of the epidermal growth factor receptor.

    C E Futter;S Felder;J Schlessinger;A Ullrich

  • Human VPS34 is required for internal vesicle formation within multivesicular endosomes

    C.E. Futter;L.M. Collinson;J.M. Backer;C.R. Hopkins

  • Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles.

    James R Edgar;James R Edgar;Emily R Eden;Clare E Futter

  • In Polarized MDCK Cells Basolateral Vesicles Arise from Clathrin-γ-adaptin–coated Domains on Endosomal Tubules

    C.E. Futter;A. Gibson;E.H. Allchin;S. Maxwell

  • Multivesicular bodies: co-ordinated progression to maturity

    Philip G Woodman;Clare E Futter

  • NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress

    D Höglinger;D Höglinger;T Burgoyne;E Sanchez-Heras;P Hartwig

  • Rab11-FIP3 links the Rab11 GTPase and cytoplasmic dynein to mediate transport to the endosomal-recycling compartment.

    Conor P. Horgan;Sara R. Hanscom;Rushee S. Jolly;Clare E. Futter

  • Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals.

    Bethan S. Kilpatrick;Emily R. Eden;Anthony H. Schapira;Clare E. Futter

  • Rab27b regulates number and secretion of platelet dense granules

    Tanya Tolmachova;Magnus Åbrink;Clare E. Futter;Kalwant S. Authi

  • Newly Synthesized Transferrin Receptors Can Be Detected in the Endosome before They Appear on the Cell Surface

    Clare E. Futter;Christopher N. Connolly;Daniel F. Cutler;Colin R. Hopkins

  • Disruption of Endocytic Trafficking in Frontotemporal Dementia with CHMP2B Mutations

    Hazel Urwin;Astrid Authier;Jorgen E. Nielsen;Jorgen E. Nielsen;Daniel Metcalf

  • Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition.

    Leanne N. Hockey;Bethan S. Kilpatrick;Emily R. Eden;Yaping Lin-Moshier

  • Annexins and endocytosis

    Clare E. Futter;Ian J. White

Frequent Co-Authors

Miguel C. Seabra
Miguel C. Seabra Universidade Nova de Lisboa
Colin R. Hopkins
Colin R. Hopkins Imperial College London
Michael E. Cheetham
Michael E. Cheetham University College London
Daniel F. Cutler
Daniel F. Cutler University College London
John Greenwood
John Greenwood University College London
Andrew R. Webster
Andrew R. Webster University College London
Sandip Patel
Sandip Patel University College London
Stephen E. Moss
Stephen E. Moss University College London
Magnus Åbrink
Magnus Åbrink Swedish University of Agricultural Sciences
Alexander Sorkin
Alexander Sorkin University of Pittsburgh

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