D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 81 Citations 22,923 225 World Ranking 972 National Ranking 525
Medicine D-index 85 Citations 25,654 249 World Ranking 9606 National Ranking 5088

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cytokine
  • Immune system

Immunology, Multiple sclerosis, Microglia, Central nervous system and Cytokine are her primary areas of study. Her Immunology research focuses on Oligodendrocyte and how it relates to Cytotoxic T cell and Remyelination. She interconnects Lesion, Pathology, Endothelium and Myelin basic protein in the investigation of issues within Multiple sclerosis.

Her Microglia study combines topics from a wide range of disciplines, such as Nitric oxide and Astrocyte. Her Astrocyte research integrates issues from Neuroglia and Cell biology. Her Central nervous system research is multidisciplinary, incorporating elements of Interleukin and Autoimmune disease.

Her most cited work include:

  • Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease (782 citations)
  • Cytokine production by human fetal microglia and astrocytes : differential induction by lipopolysaccharide and IL-1β (717 citations)
  • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. (676 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Immunology, Multiple sclerosis, Central nervous system, Cell biology and Experimental autoimmune encephalomyelitis. Her study in Immunology focuses on Microglia, Encephalomyelitis, Cytokine, Antigen and Inflammation. Celia F. Brosnan has included themes like Chemokine and Tumor necrosis factor alpha in her Cytokine study.

Her research investigates the link between Multiple sclerosis and topics such as Pathology that cross with problems in Blood–brain barrier and Spinal cord. Her Cell biology research is multidisciplinary, relying on both Proinflammatory cytokine, Receptor, Cellular differentiation and Astrocyte. As a part of the same scientific study, Celia F. Brosnan usually deals with the Astrocyte, concentrating on Molecular biology and frequently concerns with T cell.

She most often published in these fields:

  • Immunology (44.49%)
  • Multiple sclerosis (21.26%)
  • Central nervous system (19.69%)

What were the highlights of her more recent work (between 2004-2015)?

  • Immunology (44.49%)
  • Cell biology (19.29%)
  • Experimental autoimmune encephalomyelitis (19.29%)

In recent papers she was focusing on the following fields of study:

Celia F. Brosnan spends much of her time researching Immunology, Cell biology, Experimental autoimmune encephalomyelitis, Astrocyte and Multiple sclerosis. Her study in Immunology is interdisciplinary in nature, drawing from both Cannabinoid Receptor Agonists, Myelin and Cannabinoid Receptor Modulators. Her research on Cell biology also deals with topics like

  • Remyelination which is related to area like Oligodendrocyte differentiation,
  • Receptor, which have a strong connection to Endocrinology.

Her Astrocyte research includes elements of Aquaporin 4, Cytokine and Neuroglia. She has researched Multiple sclerosis in several fields, including Lesion and Transcription factor. The various areas that Celia F. Brosnan examines in her Microglia study include Proinflammatory cytokine, Innate immune system and Central nervous system.

Between 2004 and 2015, her most popular works were:

  • P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling (433 citations)
  • IL-1β Regulates Blood-Brain Barrier Permeability via Reactivation of the Hypoxia-Angiogenesis Program (216 citations)
  • Deletion of astrocyte connexins 43 and 30 leads to a dysmyelinating phenotype and hippocampal CA1 vacuolation (171 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

Her primary areas of investigation include Astrocyte, Cell biology, Neuroscience, Immunology and Receptor. Her Astrocyte research focuses on Neuroglia and how it connects with Reprogramming, Interleukin, Cytokine and Metabotropic receptor. As a part of the same scientific family, she mostly works in the field of Cell biology, focusing on Proinflammatory cytokine and, on occasion, Endothelium, Transcription factor, Neovascularization, Angiogenesis and Microglia.

Her Immunology study combines topics in areas such as Cannabinoid Receptor Modulators, Cannabinoid, Neuroprotection, Cell damage and Endocannabinoid system. Her work deals with themes such as Vesicular stomatitis virus and Endocrinology, which intersect with Receptor. Her work on Inflammation and Experimental autoimmune encephalomyelitis as part of her general Internal medicine study is frequently connected to Population, thereby bridging the divide between different branches of science.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions.

K Selmaj;C S Raine;B Cannella;C F Brosnan.
Journal of Clinical Investigation (1991)

1077 Citations

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

Dennis W. Dickson;Sunhee C. Lee;Linda A. Mattiace;Shu‐Hui C. Yen.
Glia (1993)

1051 Citations

Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta.

S. C. Lee;Wei Liu;D. W. Dickson;C. F. Brosnan.
Journal of Immunology (1993)

995 Citations

Quantitative aspects of reactive gliosis: A review

W T Norton;D A Aquino;I Hozumi;F C Chiu.
Neurochemical Research (1992)

794 Citations

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor.

K W Selmaj;M Farooq;W T Norton;C S Raine.
Journal of Immunology (1990)

669 Citations

P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling

Sylvia O. Suadicani;Celia F. Brosnan;Eliana Scemes.
The Journal of Neuroscience (2006)

589 Citations

Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin.

K Selmaj;C S Raine;M Farooq;W T Norton.
Journal of Immunology (1991)

569 Citations

Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation

Gareth R. John;Sai Latha Shankar;Bridget Shafit-Zagardo;Aldo Massimi.
Nature Medicine (2002)

540 Citations

Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ

Sunhee C. Lee;Dennis W. Dickson;Wei Liu;Celia F. Brosnan.
Journal of Neuroimmunology (1993)

510 Citations

MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study.

Carrie McManus;Joan W Berman;Francesca M Brett;Hugh Staunton.
Journal of Neuroimmunology (1998)

444 Citations

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