Bradley Spencer-Dene

Overview

Best Publications

• Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.

  Marco Gerlinger;Andrew J. Rowan;Stuart Horswell;James Larkin

  8405
  Citations

• Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

  Marco Gerlinger;Stuart Horswell;James Larkin;Andrew J Rowan

  1336
  Citations

• An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis

  L De Moerlooze;B Spencer-Dene;J M Revest;M Hajihosseini

  1226
  Citations

• Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

  Elza C. de Bruin;Nicholas McGranahan;Nicholas McGranahan;Richard Mitter;Max Salm

  1193
  Citations

• Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

  Zachary T. Schug;Barrie Peck;Dylan T. Jones;Qifeng Zhang

  757
  Citations

• Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling

  Eishu Hirata;Maria Romina Girotti;Amaya Viros;Steven Hooper

  603
  Citations

• Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA

  Matthew A. Coelho;Sophie de Carné Trécesson;Sareena Rana;Davide Zecchin

  537
  Citations

• Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

  Abdolrahman S. Nateri;Bradley Spencer-Dene;Bradley Spencer-Dene;Axel Behrens

  454
  Citations

• Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

  Ritva Rice;Bradley Spencer-Dene;Elaine C. Connor;Amel Gritli-Linde

  429
  Citations

• Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4.

  Jean-Michel Revest;Bradley Spencer-Dene;Karen Kerr;Laurence De Moerlooze

  358
  Citations

• Integrin signalling regulates YAP and TAZ to control skin homeostasis

  Ahmed Elbediwy;Zoé I. Vincent-Mistiaen;Bradley Spencer-Dene;Richard K. Stone

  337
  Citations

• Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments.

  Rafael Di Marco Barros;Rafael Di Marco Barros;Rafael Di Marco Barros;Natalie A. Roberts;Robin J. Dart;Robin J. Dart;Pierre Vantourout

  324
  Citations

• Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo

  Arnaud André Mailleux;Bradley Spencer-Dene;Christian Dillon;Delphine Ndiaye

  308
  Citations

• c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling

  Xavier Fontana;Mariya Hristova;Clive Da Costa;Smriti Patodia

  298
  Citations

• FGF/FGFR-2(IIIb) Signaling Is Essential for Inner Ear Morphogenesis

  Ulla Pirvola;Bradley Spencer-Dene;Liang Xing-Qun;Päivi Kettunen

  263
  Citations

• Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung

  Susana Aguilar;Susana Aguilar;Emma Nye;Emma Nye;Jerry Chan;Michael Loebinger

  245
  Citations

• YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK–STAT3 Signaling

  Ralph Gruber;Richard Panayiotou;Emma Nye;Bradley Spencer-Dene

  242
  Citations

• Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.

  Barrie Peck;Barrie Peck;Zachary T. Schug;Qifeng Zhang;Beatrice Dankworth

  242
  Citations

• Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization

  Yaiza del Pozo Martin;Danielle Park;Anassuya Ramachandran;Luigi Ombrato

  236
  Citations

• An Important Role for the IIIb Isoform of Fibroblast Growth Factor Receptor 2 in Mesenchymal-Epithelial Signalling during Mouse Organogenesis

  B Spencer-Dene;L De Moerlooze;C Dickson

  40
  Citations