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Chemistry

D-Index
47
Citations
8262
World Ranking
15616
National Ranking
298

Overview

Bhyravabhotla Jayaram is affiliated with the Indian Institute of Technology Delhi in India. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a significant emphasis on Molecular Biology as a subfield. The scientist's work spans several subfields, including Computational Theory and Mathematics, Materials Chemistry, Genetics, and Public Health, Environmental, and Occupational Health.

The main topics in Jayaram's research include Protein Structure and Dynamics, Computational Drug Discovery Methods, and RNA and Protein Synthesis Mechanisms. Additional areas covered are Machine Learning in Bioinformatics, Enzyme Structure and Function, DNA and Nucleic Acid Chemistry, and Genetics, Bioinformatics, and Biomedical Research.

They have published numerous scientific articles in a range of venues. Frequent publication platforms include Zenodo (CERN European Organization for Nuclear Research), Scientific Reports, Frontiers in Molecular Biosciences, International Journal of Research Innovation and Commercialisation, and SSRN Electronic Journal.

Recent papers authored by or associated with Jayaram include:

  • Evaluation of novobiocin and telmisartan for anti-CHIKV activity, 2020, Virology
  • RASPD+: Fast Protein-Ligand Binding Free Energy Prediction Using Simplified Physicochemical Features, 2020, Frontiers in Molecular Biosciences
  • Enhancing protein backbone angle prediction by using simpler models of deep neural networks, 2020, Scientific Reports
  • Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin, 2020, Endocrinology
  • A novel methodSEPromfor prokaryotic promoter prediction based on DNA structure and energetics, 2020, Bioinformatics

Jayaram has collaborated frequently with several co-authors, including:

  • Amita Pathak
  • Stefan Holderbach
  • Lukas Adam
  • Rebecca C. Wade
  • Goutam Mukherjee

Best Publications

  • Intrusion of Counterions into the Spine of Hydration in the Minor Groove of B-DNA: Fractional Occupancy of Electronegative Pockets

    Matthew A. Young;B. Jayaram;D. L. Beveridge

  • The electrostatic potential of B-DNA.

    B. Jayaram;Kim A. Sharp;Barry Honig

  • A systematic molecular dynamics study of nearest-neighbor effects on base pair and base pair step conformations and fluctuations in B-DNA

    Richard Lavery;Krystyna Zakrzewska;David Beveridge;Thomas C. Bishop

  • Solvation Free Energy of Biomacromolecules: Parameters for a Modified Generalized Born Model Consistent with the AMBER Force Field

    B. Jayaram;D. Sprous;D. L. Beveridge

  • The Role of Water in Protein-DNA Recognition

    B. Jayaram;Tarun Jain

  • Sanjeevini: a freely accessible web-server for target directed lead molecule discovery.

    Bhyravabhotla Jayaram;Tanya Singh;Goutam Mukherjee;Abhinav Mathur

  • Free energy calculations of ion hydration: an analysis of the Born model in terms of microscopic simulations

    B. Jayaram;Richard Fine;Kim Sharp;Barry Honig

  • μABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA

    Marco Pasi;John H. Maddocks;David Beveridge;Thomas C. Bishop

  • Free Energy Analysis of the Conformational Preferences of A and B Forms of DNA in Solution

    B. Jayaram;D. Sprous;M. A. Young;D. L. Beveridge

  • AADS--an automated active site identification, docking, and scoring protocol for protein targets based on physicochemical descriptors

    Tanya Singh;D. Biswas;Bhyravabhotla Jayaram

  • Do water molecules mediate protein-DNA recognition?

    Ch.Koti Reddy;Achintya Das;B. Jayaram

  • Local dielectric environment of B-DNA in solution : Results from a 14 ns molecular dynamics trajectory

    M. A. Young;B. Jayaram;D. L. Beveridge

  • Modeling DNA in Aqueous Solutions: Theoretical and Computer Simulation Studies on the Ion Atmosphere of DNA

    Jayaram B;Beyeridge Dl

  • Free Energy Analysis of Protein-DNA Binding

    B Jayaram;K.J McConnell;Surjit B Dixit;D.L Beveridge

  • ParDOCK: an all atom energy based Monte Carlo docking protocol for protein-ligand complexes.

    A. Gupta;A. Gandhimathi;P. Sharma;B. Jayaram

  • A molecular thermodynamic view of DNA-drug interactions: a case study of 25 minor-groove binders.

    Saher Afshan Shaikh;Sajeedha Reshmi Ahmed;B. Jayaram

  • Bhageerath: an energy based web enabled computer software suite for limiting the search space of tertiary structures of small globular proteins

    B. Jayaram;Kumkum Bhushan;Sandhya R. Shenoy;Pooja Narang

  • A stoichiometry driven universal spatial organization of backbones of folded proteins: are there Chargaff's rules for protein folding?

    Aditya Mittal;B. Jayaram;Sandhya Shenoy;Tejdeep Singh Bawa

  • Free‐energy component analysis of 40 protein–DNA complexes: A consensus view on the thermodynamics of binding at the molecular level

    B. Jayaram;K. McConnell;Surjit B. Dixit;Surjit B. Dixit;A. Das

  • Proteins: Sequence to Structure and Function – Current Status

    Sandhya R. Shenoy;B. Jayaram

  • Monte Carlo simulation studies on the structure of the counterion atmosphere of B-DNA. Variations on the primitive dielectric model

    B. Jayaram;S. Swaminathan;D. L. Beveridge;K. Sharp

  • An all atom energy based computational protocol for predicting binding affinities of protein-ligand complexes.

    Tarun Jain;B. Jayaram

Frequent Co-Authors

David L. Beveridge
David L. Beveridge Wesleyan University
Rebecca C. Wade
Rebecca C. Wade Heidelberg Institute for Theoretical Studies
Barry Honig
Barry Honig Columbia University
Shoba Ranganathan
Shoba Ranganathan Macquarie University
Abdul Sattar
Abdul Sattar Griffith University
Faizan Ahmad
Faizan Ahmad Jamia Millia Islamia
Kim A. Sharp
Kim A. Sharp University of Pennsylvania
Charles A. Laughton
Charles A. Laughton University of Nottingham
Abdollah Dehzangi
Abdollah Dehzangi Rutgers, The State University of New Jersey
Avinash Mishra
Avinash Mishra Central Salt and Marine Chemicals Research Institute

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