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Biology and Biochemistry

D-Index
56
Citations
12075
World Ranking
14372
National Ranking
1017

Overview

Wolfgang Siess is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily focuses on the field of Medicine, with particular attention to subfields such as Hematology, Genetics, Pathology and Forensic Medicine, Surgery, and Infectious Diseases.

The main topics of their work cover areas including Platelet Disorders and Treatments, Autoimmune Bullous Skin Diseases, Heparin-Induced Thrombocytopenia and Thrombosis, Chronic Lymphocytic Leukemia Research, Blood Groups and Transfusion, Chronic Myeloid Leukemia Treatments, and Chemokine Receptors and Signaling.

Wolfgang Siess has collaborated frequently with several co-authors, notably Philipp von Hundelshausen, Christian Weber, Reinhard Lorenz, Rundan Duan, and Remco T. A. Megens.

Their publications appear in various scientific venues, with multiple contributions to:

  • Thrombosis and Haemostasis
  • Cancers
  • Blood
  • Frontiers in Cardiovascular Medicine
  • Cardiovascular Research

Some recent papers authored or co-authored by Wolfgang Siess include:

  • "Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): Targeting Pathomechanisms with Bruton Tyrosine Kinase Inhibitors," 2021, Thrombosis and Haemostasis
  • "Bleeding by Bruton Tyrosine Kinase-Inhibitors: Dependency on Drug Type and Disease," 2021, Cancers
  • "Targeting platelet-derived CXCL12 impedes arterial thrombosis," 2022, Blood
  • "Effects of the Btk-Inhibitors Remibrutinib (LOU064) and Rilzabrutinib (PRN1008) With Varying Btk Selectivity Over Tec on Platelet Aggregation and in vitro Bleeding Time," 2021, Frontiers in Cardiovascular Medicine
  • "Glycoprotein VI is not a Functional Platelet Receptor for Fibrin Formed in Plasma or Blood," 2020, Thrombosis and Haemostasis

Best Publications

  • PLATELET-MEMBRANE FATTY ACIDS, PLATELET AGGREGATION, AND THROMBOXANE FORMATION DURING A MACKEREL DIET

    W. Siess;B. Scherer;B. Böhlig;P. Roth

  • Multiple electrode aggregometry: A new device to measure platelet aggregation in whole blood

    Orsolya Tóth;Andreas Calatzis;Sandra Penz;Hajna Losonczy

  • Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions.

    Wolfgang Siess;Konrad J. Zangl;Markus Essler;Markus Bauer

  • Increased Adhesion and Aggregation of Platelets Lacking Cyclic Guanosine 3′,5′-Monophosphate Kinase I

    Steffen Massberg;Matthias Sausbier;Peter Klatt;Markus Bauer

  • Subtype-Selective Antagonists of Lysophosphatidic Acid Receptors Inhibit Platelet Activation Triggered by the Lipid Core of Atherosclerotic Plaques

    Enno Rother;Richard Brandl;Daniel L. Baker;Pankaj Goyal

  • Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation.

    W Siess;F L Siegel;E G Lapetina

  • Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate.

    Wolfgang Siess

  • Dichotomous Regulation of Myosin Phosphorylation and Shape Change by Rho-Kinase and Calcium in Intact Human Platelets

    Markus Bauer;Michaela Retzer;Jonathan I. Wilde;Petra Maschberger

  • A 2-Step Mechanism of Arterial Thrombus Formation Induced by Human Atherosclerotic Plaques

    Armin J. Reininger;Isabell Bernlochner;Sandra M. Penz;Catherine Ravanat

  • Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI

    Sandra Penz;Armin J. Reininger;Richard Brandl;Pankaj Goyal

  • Plasma catecholamines, platelet aggregation and associated thromboxane formation after physical exercise, smoking or norepinephrine infusion.

    W Siess;R Lorenz;P Roth;P C Weber

  • Mildly oxidized LDL induces platelet aggregation through activation of phospholipase A2.

    A. Weidtmann;R. Scheithe;N. Hrboticky;A. Pietsch

  • Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change.

    W Siess;P C Weber;E G Lapetina

  • Inhibitors of protein tyrosine kinase suppress TNF-stimulated induction of endothelial cell adhesion molecules.

    C Weber;E Negrescu;W Erl;A Pietsch

  • Unique Ligand Selectivity of the GPR92/LPA5 Lysophosphatidate Receptor Indicates Role in Human Platelet Activation

    Jesica R. Williams;Anna L. Khandoga;Pankaj Goyal;James I. Fells

  • A role for cyclooxygenase products in the formation of phosphatidic acid in stimulated human platelets. Differential mechanisms of action of thrombin and collagen.

    W Siess;P Cuatrecasas;E G Lapetina

  • Mildly oxidized low density lipoprotein induces contraction of human endothelial cells through activation of Rho/Rho kinase and inhibition of myosin light chain phosphatase.

    Markus Essler;Michaela Retzer;Markus Bauer;Johan W. Heemskerk

  • Thrombogenic and atherogenic activities of lysophosphatidic acid.

    Wolfgang Siess;Gabor Tigyi

  • The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors.

    Nadine Haserück;Wolfgang Erl;Wolfgang Erl;Wolfgang Erl;Dharmendra Pandey;Dharmendra Pandey;Dharmendra Pandey;Gabor Tigyi;Gabor Tigyi;Gabor Tigyi

  • A comparative study of eicosapentaenoic acid metabolism by human platelets in vivo and in vitro.

    C von Schacky;W Siess;S Fischer;P C Weber

Frequent Co-Authors

Christian Weber
Christian Weber Ludwig-Maximilians-Universität München
Eduardo G. Lapetina
Eduardo G. Lapetina Case Western Reserve University
Gabor Tigyi
Gabor Tigyi University of Tennessee Health Science Center
Steve P. Watson
Steve P. Watson University of Birmingham
Martin Aepfelbacher
Martin Aepfelbacher Universität Hamburg
Richard W. Farndale
Richard W. Farndale University of Cambridge
Duane D. Miller
Duane D. Miller University of Tennessee Health Science Center
Oliver Soehnlein
Oliver Soehnlein University of Münster
Steffen Massberg
Steffen Massberg Ludwig-Maximilians-Universität München
Bernhard Nieswandt
Bernhard Nieswandt University of Würzburg

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