World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
8203
World Ranking
12859
National Ranking
920

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary scientific interests are in Biochemistry, Molecular biology, Sponge, Enzyme and Cell biology. He has researched Molecular biology in several fields, including Polymerase, Gene expression, RNA, Messenger RNA and Direct fluorescent antibody. His Sponge study integrates concerns from other disciplines, such as DNA, Ecology, Programmed cell death and Cell growth.

His Enzyme study combines topics in areas such as Divalent and DNA synthesis. His Cell biology research includes elements of Cell culture, Glycosyltransferase and Cellular differentiation. W. E. G. Müller focuses mostly in the field of Cell culture, narrowing it down to matters related to RNase P and, in some cases, Virus and Virology.

His most cited work include:

  • Establishment of a primary cell culture from a sponge: primmorphs from Suberites domuncula (163 citations)
  • Specific phosphorylation of proteins in pore complex-laminae from the sponge Geodia cydonium by the homologous aggregation factor and phorbol ester. Role of protein kinase C in the phosphorylation of DNA topoisomerase II. (116 citations)
  • Cordycepin analogues of 2',5'-oligoadenylate inhibit human immunodeficiency virus infection via inhibition of reverse transcriptase. (114 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Molecular biology, Biochemistry, Sponge, Virology and Cell biology. He has included themes like RNA, Messenger RNA, Gene expression, Gene and DNA in his Molecular biology study. His study ties his expertise on Divalent together with the subject of Biochemistry.

The Sponge study combines topics in areas such as Ecology and Stereochemistry. As part of the same scientific family, W. E. G. Müller usually focuses on Virology, concentrating on Antigen and intersecting with Antibody. His research in Cell biology intersects with topics in Receptor and Programmed cell death.

He most often published in these fields:

  • Molecular biology (33.94%)
  • Biochemistry (32.73%)
  • Sponge (20.61%)

What were the highlights of his more recent work (between 2000-2014)?

  • Sponge (20.61%)
  • Suberites domuncula (6.67%)
  • Cell biology (13.33%)

In recent papers he was focusing on the following fields of study:

W. E. G. Müller spends much of his time researching Sponge, Suberites domuncula, Cell biology, Biochemistry and Microbiology. In his study, Exon, cDNA library and Stop codon is inextricably linked to Sponge spicule, which falls within the broad field of Sponge. His Suberites domuncula research is multidisciplinary, relying on both Lipopolysaccharide, Demosponge, Phylogenetic tree and Bacteria.

His biological study spans a wide range of topics, including Mytilus, Cellular differentiation, Immune system and Mussel. His Biochemistry study incorporates themes from Strain and Alkaloid. His research in Gene focuses on subjects like Molecular biology, which are connected to Programmed cell death.

Between 2000 and 2014, his most popular works were:

  • Silicate modulates the cross‐talk between osteoblasts (SaOS‐2) and osteoclasts (RAW 264.7 cells): Inhibition of osteoclast growth and differentiation (80 citations)
  • Molecular response of the sponge Suberites domuncula to bacterial infection (73 citations)
  • Molecular phylogeny of the freshwater sponges in Lake Baikal (56 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Suberites domuncula, Sponge, Biochemistry, Bacteria and Cell biology. His Suberites domuncula research is multidisciplinary, incorporating perspectives in Vibrio, Vibrionaceae, Mitogen-activated protein kinase, Microbiology and Pseudomonas. His Sponge research incorporates elements of Evolutionary biology, Bicyclic molecule, Fungus and Alkaloid.

Much of his study explores Biochemistry relationship to Strain. His studies deal with areas such as Innate immune system, p38 mitogen-activated protein kinases and Lysozyme as well as Bacteria. The concepts of his Cell biology study are interwoven with issues in Cellular differentiation, Chemotaxis, Immune system, Echinoderm and Fishery.

Best Publications

  • Establishment of a primary cell culture from a sponge: primmorphs from Suberites domuncula

    Weg Müller;M. Wiens;R. Batel;R. Steffen

  • Cordycepin analogues of 2',5'-oligoadenylate inhibit human immunodeficiency virus infection via inhibition of reverse transcriptase.

    W. E. G. Muller;B. E. Weiler;R. Charubala;W. Pfleiderer

  • Evidence for a symbiosis between bacteria of the genus Rhodobacter and the marine sponge Halichondria panicea : harbor also for putatively toxic bacteria ?

    K. Althoff;C. Schütt;R. Steffen;R. Batel

  • Specific phosphorylation of proteins in pore complex-laminae from the sponge Geodia cydonium by the homologous aggregation factor and phorbol ester. Role of protein kinase C in the phosphorylation of DNA topoisomerase II.

    M. Rottmann;H. C. Schröder;M. Gramzow;K. Renneisen

  • Early evolution of metazoan serine/threonine and tyrosine kinases: identification of selected kinases in marine sponges.

    M. Kruse;I. M. Muller;W. E. G. Muller

  • INHIBITION OF HERPESVIRUS DNA SYNTHESIS BY 9-β-D-ARABINOFURANOSYLADENINE IN CELLULAR AND CELL-FREE SYSTEMS *

    W. E. G. Müller;R. K. Zahn;K. Bittlingmaier;D. Falke

  • Inhibition of expression of human immunodeficiency virus-1 in vitro by antibody-targeted liposomes containing antisense RNA to the env region.

    K Renneisen;L Leserman;E Matthes;H C Schröder

  • Polyphosphate in bone.

    H. C. Schröder;L. Kurz;W. E. G. Müller;B. Lorenz

  • Interferon Production in Patients Infected with HIV-1

    S. Rossol;R. Voth;H. P. Laubenstein;W. E. G. Müller

  • Application of cell culture for the production of bioactive compounds from sponges: synthesis of avarol by primmorphs from Dysidea avara.

    Müller We;Böhm M;Batel R;De Rosa S

  • On the origin of Metazoan adhesion receptors: cloning of integrin alpha subunit from the sponge Geodia cydonium.

    Z Pancer;M Kruse;I Müller;W E Müller

  • Origin of neuronal-like receptors in Metazoa: cloning of a metabotropic glutamate/GABA-like receptor from the marine sponge Geodia cydonium

    Sanja Perovic;Anatoli Krasko;I. Prokic;Isabel M. Müller

  • Molecular mechanisms determining the strength of receptor-mediated intermembrane adhesion

    Deborah E Leckband;W. Müller;F. J. Schmitt;H. Ringsdorf

  • Association of La and Ro antigens with intracellular structures in HEp-2 carcinoma cells.

    M. Bachmann;W. J. Mayet;H. C. Schröder;K. Pfeifer

  • The putative sponge aggregation receptor. Isolation and characterization of a molecule composed of scavenger receptor cysteine-rich domains and short consensus repeats.

    B. Blumbach;Z. Pancer;B. Diehl-Seifert;R. Steffen

  • Modulation of nuclear matrix-associated 2',5'-oligoadenylate metabolism and ribonuclease L activity in H9 cells by human immunodeficiency virus.

    H C Schröder;R Wenger;Y Kuchino;W E G Müller

  • Molecular response of the sponge Suberites domuncula to bacterial infection

    M. Böhm;U. Hentschel;A. B. Friedrich;L. Fieseler

  • Silicate modulates the cross‐talk between osteoblasts (SaOS‐2) and osteoclasts (RAW 264.7 cells): Inhibition of osteoclast growth and differentiation

    H.C. Schröder;X.H. Wang;M. Wiens;B. Diehl-Seifert

  • Monitoring chemical and physical stress using sea urchin immune cells.

    V. Matranga;A. Pinsino;M. Celi;A. Natoli

  • Differential gene expression of IFN-alpha and tumor necrosis factor-alpha in peripheral blood mononuclear cells from patients with AIDS related complex and AIDS.

    R. Voth;S. Rossol;K. Klein;G. Hess

Frequent Co-Authors

Rudolf K. Zahn
Rudolf K. Zahn Johannes Gutenberg University of Mainz
Isabel M. Müller
Isabel M. Müller Johannes Gutenberg University of Mainz
Michael Bachmann
Michael Bachmann Helmholtz-Zentrum Dresden-Rossendorf
Renato Batel
Renato Batel Institut Ruđer Bošković
Matthias Wiens
Matthias Wiens Johannes Gutenberg University of Mainz
Heinz C. Schröder
Heinz C. Schröder Johannes Gutenberg University of Mainz
K.-H. Meyer zum Büschenfelde
K.-H. Meyer zum Büschenfelde Johannes Gutenberg University of Mainz
Yoshiyuki Kuchino
Yoshiyuki Kuchino National Cancer Research Institute, UK
Deborah E. Leckband
Deborah E. Leckband University of Illinois at Urbana-Champaign
Helmut Ringsdorf
Helmut Ringsdorf Johannes Gutenberg University of Mainz

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