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Medicine

D-Index
91
Citations
32538
World Ranking
11702
National Ranking
6004

Overview

Timothy C. Thompson is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on medicine as a broad field, with particular emphasis on subfields such as pulmonary and respiratory medicine, molecular biology, oncology, cancer research, and immunology.

The scientist's work covers several main topics, notably prostate cancer treatment and research, prostate cancer diagnosis and treatment, PARP inhibition in cancer therapy, cancer related to lipids and metabolism, caveolin-1 and cellular processes, interferon and immune responses, and epigenetics and DNA methylation.

Thompson has coauthored research extensively with a number of frequent collaborators, including Nora M. Navone, Gail P. Risbridger, Renea A. Taylor, Samuel R. Denmeade, and Tamara L. Lotan.

Their body of published work includes papers appearing in a range of journals, with notable frequent publication venues such as The Prostate, Journal of Clinical Oncology, Clinical Cancer Research, Nature Reviews Urology, and bioRxiv (Cold Spring Harbor Laboratory).

Representative recent papers authored by or involving Thompson include:

  • Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma (2020) published in Cancer Cell
  • ATR Inhibition Induces CDK1-SPOP Signaling and Enhances Anti-PD-L1 Cytotoxicity in Prostate Cancer (2021) published in Clinical Cancer Research
  • Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer (2020) published in Nature Communications
  • The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62 (2022) published in Cell Reports
  • PARP and CDK4/6 Inhibitor Combination Therapy Induces Apoptosis and Suppresses Neuroendocrine Differentiation in Prostate Cancer (2021) published in Molecular Cancer Therapeutics

In addition to journal articles, Thompson has contributed to book publications. They have published work with Kellogg School of Management eBooks, including the title Bed Bath & Beyond: The Capital Structure Decision, scheduled for 2025.

Best Publications

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • p53 mutant mice that display early ageing-associated phenotypes

    Stuart D. Tyner;Sundaresan Venkatachalam;Jene Choi;Stephen Jones

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches

    Theodoros Karantanos;Paul G. Corn;Timothy C. Thompson

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • ELEVATED LEVELS OF CIRCULATING INTERLEUKIN-6 AND TRANSFORMING GROWTH FACTOR-beta 1 IN PATIENTS WITH METASTATIC PROSTATIC CARCINOMA

    Howard L. Adler;Mark A. McCURDY;Michael W. Kattan;Terry L. Timme

  • Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ

    Timothy C. Thompson;Jennifer Southgate;Hartmut Land

  • Elevated expression of caveolin is associated with prostate and breast cancer.

    Guang Yang;Luan D. Truong;Terry L. Timme;Chengzhen Ren

  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi

  • CD8+ Foxp3+ Regulatory T Cells Mediate Immunosuppression in Prostate Cancer

    Yukiko Kiniwa;Yoshihiro Miyahara;Helen Yicheng Wang;Weiyi Peng

  • Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A

    Likun Li;Cheng Hui Ren;Salahaldin A. Tahir;Chengzhen Ren

  • Caveolin-1 expression in clinically confined human prostate cancer: a novel prognostic marker.

    Guang Yang;Luan D. Truong;Thomas M. Wheeler;Timothy C. Thompson

  • In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial.

    James R. Herman;Howard L. Adler;Estuardo Aguilar-Cordova;Augusto Rojas-Martinez

  • Reduced Infiltration of Tumor-associated Macrophages in Human Prostate Cancer: Association with Cancer Progression

    Satoru Shimura;Guang Yang;Shin Ebara;Thomas M. Wheeler

  • Cancer-Related Axonogenesis and Neurogenesis in Prostate Cancer

    Gustavo E. Ayala;Hong Dai;Michael Powell;Rile Li

  • Effects of genetic background on tumorigenesis in p53-deficient mice

    Lawrence A. Donehower;Michele Harvey;Michele Harvey;Hannes Vogel;Mark J. McArthur

  • Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer.

    Salahaldin A. Tahir;Guang Yang;Shin Ebara;Terry L. Timme

  • Understanding the mechanisms of androgen deprivation resistance in prostate cancer at the molecular level.

    Theodoros Karantanos;Christopher P. Evans;Bertrand Tombal;Timothy C. Thompson

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

Frequent Co-Authors

Thomas M. Wheeler
Thomas M. Wheeler Baylor College of Medicine
Michael Ittmann
Michael Ittmann Baylor College of Medicine
Peter T. Scardino
Peter T. Scardino Memorial Sloan Kettering Cancer Center
Luan D. Truong
Luan D. Truong Cornell University
Lawrence A. Donehower
Lawrence A. Donehower Baylor College of Medicine
Peter R. Carroll
Peter R. Carroll University of California, San Francisco
Steven E. Schumacher
Steven E. Schumacher Broad Institute
Andrew D. Cherniack
Andrew D. Cherniack Broad Institute
Christina Yau
Christina Yau University of California, San Francisco
Matthew Meyerson
Matthew Meyerson Harvard University

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