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Molecular Biology

D-Index
44
Citations
12094
World Ranking
2898
National Ranking
1383

Overview

Shuibing Chen is affiliated with Cornell University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant focus on subfields such as Molecular Biology, Infectious Diseases, Surgery, Genetics, and Immunology.

Their work addresses key topics including pancreatic function and diabetes, SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, pluripotent stem cells research, CRISPR and genetic engineering, diabetes and associated disorders, as well as single-cell and spatial transcriptomics.

Shuibing Chen's frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell stem cell
  • Cell Reports
  • Zenodo (CERN European Organization for Nuclear Research)
  • Diabetes

Notable recent papers authored or co-authored by Chen are:

  • A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids, 2020, Cell Stem Cell
  • Identification of SARS-CoV-2 inhibitors using lung and colonic organoids, 2020, Nature
  • SARS-CoV-2 infection induces beta cell transdifferentiation, 2021, Cell Metabolism
  • Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children, 2022, Science
  • Human organoid models to study SARS-CoV-2 infection, 2022, Nature Methods

Shuibing Chen frequently collaborates with a core group of co-authors, including:

  • Todd Evans
  • Tuo Zhang
  • Robert E. Schwartz
  • Yuling Han
  • Jenny Xiang

Best Publications

  • Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.

    Danwei Huangfu;Kenji Osafune;René Maehr;Wenjun Guo

  • Generation of pluripotent stem cells from patients with type 1 diabetes.

    René Maehr;Shuibing Chen;Melinda Snitow;Thomas Ludwig

  • A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.

    Liuliu Yang;Yuling Han;Benjamin E. Nilsson-Payant;Vikas Gupta

  • Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.

    Shuyuan Yao;Shuibing Chen;Julie Clark;Ergeng Hao

  • A small molecule that directs differentiation of human ESCs into the pancreatic lineage

    Shuibing Chen;Shuibing Chen;Malgorzata Borowiak;Julia L Fox;René Maehr;René Maehr

  • Small Molecules Efficiently Direct Endodermal Differentiation of Mouse and Human Embryonic Stem Cells

    Malgorzata Borowiak;René Maehr;René Maehr;Shuibing Chen;Shuibing Chen;Alice E. Chen;Alice E. Chen

  • Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.

    Yuling Han;Xiaohua Duan;Xiaohua Duan;Liuliu Yang;Benjamin E. Nilsson-Payant

  • Dedifferentiation of Lineage-Committed Cells by a Small Molecule

    Shuibing Chen;Qisheng Zhang;Xu Wu;Peter G. Schultz

  • Self-renewal of embryonic stem cells by a small molecule

    Shuibing Chen;Jeong Tae Do;Qisheng Zhang;Shuyuan Yao

  • The Renewal and Differentiation of Isl1+ Cardiovascular Progenitors Are Controlled by a Wnt/β-Catenin Pathway

    Yibing Qyang;Silvia Martin-Puig;Murali Chiravuri;Shuibing Chen

  • Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

    Miguel Crespo;Eduardo Vilar;Su Yi Tsai;Kyle Chang

  • High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain

    Ting Zhou;Lei Tan;Gustav Y. Cederquist;Yujie Fan

  • A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages.

    Jason Tchieu;Bastian Zimmer;Faranak Fattahi;Sadaf Amin

  • SARS-CoV-2 Infection Induces Beta Cell Transdifferentiation

    Xuming Tang;Skyler Uhl;Tuo Zhang;Dongxiang Xue

  • Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development

    Zhong-Dong Shi;Kihyun Lee;Dapeng Yang;Sadaf Amin

  • An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery

    Hui Zeng;Min Guo;Ting Zhou;Lei Tan

  • Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

    Yuling Han;Liuliu Yang;Xiaohua Duan;Fuyu Duan

  • Reversine increases the plasticity of lineage-committed mammalian cells.

    Shuibing Chen;Shinichi Takanashi;Qisheng Zhang;Wen Xiong

  • Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation

    Qing V. Li;Qing V. Li;Gary Dixon;Gary Dixon;Nipun Verma;Nipun Verma;Bess P. Rosen;Bess P. Rosen

  • An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis

    Logan A. Walsh;Mariano J. Alvarez;Erich Y. Sabio;Marsha Reyngold

Frequent Co-Authors

Todd Evans
Todd Evans Cornell University
Robert E. Schwartz
Robert E. Schwartz Cornell University
Benjamin R. tenOever
Benjamin R. tenOever Icahn School of Medicine at Mount Sinai
Sheng Ding
Sheng Ding Tsinghua University
David D. Ho
David D. Ho Columbia University
Peter G. Schultz
Peter G. Schultz Scripps Research Institute
Douglas A. Melton
Douglas A. Melton Harvard University
Yaoxing Huang
Yaoxing Huang Columbia University
Hui Wang
Hui Wang Chinese Academy of Sciences
Lorenz Studer
Lorenz Studer Memorial Sloan Kettering Cancer Center

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