World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
10289
World Ranking
12757
National Ranking
5439

Research.com Recognitions

  • 1974 - Fellow of Alfred P. Sloan Foundation

Overview

Ronald W. Holz is affiliated with the University of Michigan-Ann Arbor in the United States. Their research intersects primarily the fields of Biochemistry, Genetics and Molecular Biology, along with Neuroscience. Within these areas, their subfields of study include Molecular Biology, Cellular and Molecular Neuroscience, and Cell Biology.

The scientist's work addresses several main topics, including:

  • Cellular transport and secretion
  • Ion channel regulation and function
  • Lipid Membrane Structure and Behavior
  • Photoreceptor and optogenetics research
  • Neuropeptides and Animal Physiology
  • Receptor Mechanisms and Signaling
  • Retinal Development and Disorders

Their recent publications illustrate an active engagement with cellular and molecular processes related to secretion and membrane dynamics. Selected papers include:

  • "Basal and Stress-Induced Network Activity in the Adrenal Medulla In Vivo," 2022, Frontiers in Endocrinology
  • "Roles for the SNAP25 linker domain in the fusion pore and a dynamic plasma membrane SNARE 'acceptor' complex," 2020, The Journal of General Physiology
  • "Roles for the SNAP25 Linker Domain in the Fusion Pore and a Dynamic Plasma Membrane SNARE Acceptor Complex," 2020, Preprints.org
  • "VAMP2 AND SYNAPTOTAGMINS ARE RELATIVELY IMMOBILE ON CHROMAFFIN GRANULE MEMBRANES: IMPLICATIONS FOR MEMBRANE FUSION AND FUSION PORE EXPANSION," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "Stress related network activity in the intact adrenal medulla," 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequently publishing in venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Endocrinology, The Journal of General Physiology, and Preprints.org, the scientist's output spans preprints and peer-reviewed journals.

Collaborations are a notable aspect of their academic profile. Frequent co-authors in their publications include José Roberto López Ruiz, Stephen A. Ernst, Edward L. Stuenkel, Mary A. Bittner, and Prabhodh S. Abbineni. These repeated partnerships highlight ongoing research connections in related scientific investigations.

Award recognition includes their designation as a Fellow of the Alfred P. Sloan Foundation in 1974.

Best Publications

  • α-Latrotoxin Stimulates Exocytosis by the Interaction with a Neuronal G-Protein-Coupled Receptor

    Valery G Krasnoperov;Mary A Bittner;Ronald Beavis;Yanan Kuang

  • Catecholamine secretion from digitonin-treated adrenal medullary chromaffin cells.

    L A Dunn;R W Holz

  • Evidence for the involvement of Rab3A in Ca(2+)-dependent exocytosis from adrenal chromaffin cells.

    Ronald W. Holz;William H. Brondyk;Ruth A. Senter;Luzette Kuizon

  • Intracellular Ca2+ activates phospholipase C.

    David Allan Eberhard;Ronald W. Holz

  • Relationship between Ca2+ uptake and catecholamine secretion in primary dissociated cultures of adrenal medulla.

    Ronald W. Holz;Ruth A. Senter;Roy A. Frye

  • Kinetic analysis of secretion from permeabilized adrenal chromaffin cells reveals distinct components.

    Mary A. Bittner;Ronald W. Holz

  • MgATP-independent and MgATP-dependent exocytosis. Evidence that MgATP primes adrenal chromaffin cells to undergo exocytosis.

    R W Holz;M A Bittner;S C Peppers;R A Senter

  • A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2 as Being Important in Exocytosis *

    Ronald W. Holz;Michael D. Hlubek;Scott D. Sorensen;Stephen K. Fisher

  • Muscarinic Receptors in Chromaffin Cell Cultures Mediate Enhanced Phospholipid Labeling but Not Catecholamine Secretion

    Stephen K. Fisher;Ronald W. Holz;Bernard W. Agranoff

  • Isolated light chains of botulinum neurotoxins inhibit exocytosis. Studies in digitonin-permeabilized chromaffin cells.

    M A Bittner;B R DasGupta;R W Holz

  • Evidence That the Rab3a-binding Protein, Rabphilin3a, Enhances Regulated Secretion. STUDIES IN ADRENAL CHROMAFFIN CELLS

    Sul Hee Chung;Yoshimi Takai;Ronald W. Holz

  • Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate-sensitive chromaffin cells.

    P.F. Wick;R.A. Senter;L.A. Parsels;M.D. Uhler

  • Restriction of Secretory Granule Motion near the Plasma Membrane of Chromaffin Cells

    Laura M. Johns;Edwin S. Levitan;Eric A. Shelden;Ronald W. Holz

  • Cholinergic Stimulation of Inositol Phosphate Formation in Bovine Adrenal Chromaffin Cells: Distinct Nicotinic and Muscarinic Mechanisms

    David A. Eberhard;Ronald W. Holz

  • Effects of phorbol esters, diglyceride, and cholinergic agonists on the subcellular distribution of protein kinase C in intact or digitonin-permeabilized adrenal chromaffin cells.

    D R TerBush;R W Holz

  • Regulation of presynaptic phosphatidylinositol 4,5-biphosphate by neuronal activity

    Kristina D. Micheva;Ronald W. Holz;Stephen J. Smith

  • Guanine nucleotide effects on catecholamine secretion from digitonin-permeabilized adrenal chromaffin cells.

    M A Bittner;R W Holz;R R Neubig

  • Localized topological changes of the plasma membrane upon exocytosis visualized by polarized TIRFM

    Arun Anantharam;Bibiana Onoa;Robert H. Edwards;Ronald W. Holz

  • Visualization of regulated exocytosis with a granule-membrane probe using total internal reflection microscopy

    Miriam W. Allersma;Li Wang;Daniel Axelrod;Ronald W. Holz

  • Retrograde regulation of synaptic vesicle endocytosis and recycling

    Kristina D. Micheva;Jo Ann Buchanan;Ronald W. Holz;Stephen J. Smith

Frequent Co-Authors

Bernard W. Agranoff
Bernard W. Agranoff University of Michigan–Ann Arbor
Randolph Y. Hampton
Randolph Y. Hampton University of California, San Diego
Sandra L. Schmid
Sandra L. Schmid The University of Texas Southwestern Medical Center
Edwin S. Levitan
Edwin S. Levitan University of Pittsburgh
Glenn D. Prestwich
Glenn D. Prestwich University of Utah
Stephen A. Ernst
Stephen A. Ernst University of Michigan–Ann Arbor
Michael A. Sutton
Michael A. Sutton University of Michigan–Ann Arbor
Stephen J. Smith
Stephen J. Smith Allen Institute for Brain Science
Robert H. Edwards
Robert H. Edwards University of California, San Francisco
Margaret E. Gnegy
Margaret E. Gnegy University of Michigan–Ann Arbor

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