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Neuroscience

D-Index
42
Citations
5915
World Ranking
7708
National Ranking
3307

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Margaret E. Gnegy is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple areas within neuroscience and molecular biology, with a particular focus on neurotransmitter receptor influence on behavior and receptor mechanisms and signaling. They have contributed to the understanding of autism spectrum disorder through their work on these topics.

The scientist's publication record includes contributions to the field of neuroscience, biochemistry, genetics, and molecular biology. Their work is segmented into subfields such as cellular and molecular neuroscience, molecular biology, and cognitive neuroscience. This multidisciplinary approach reflects in their research outputs and collaborative efforts.

Margaret E. Gnegy has published in the journal Experimental and Clinical Psychopharmacology. One noted recent paper is titled "PKC inhibition decreases amphetamine-maintained responding under a progressive-ratio schedule of reinforcement," published in 2020. This publication addresses the effects of protein kinase C inhibition on behavior maintained by amphetamine reinforcement schedules.

Frequent co-authors collaborating with Margaret E. Gnegy include:

  • Rachel D. Altshuler
  • Ryan C Mac
  • Emily M. Jutkiewicz

Among the main topics covered in their research are:

  • Neurotransmitter Receptor Influence on Behavior
  • Receptor Mechanisms and Signaling
  • Autism Spectrum Disorder Research

Publications have appeared primarily in:

  • Experimental and Clinical Psychopharmacology

Margaret E. Gnegy's contributions to science have been recognized with their election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2018.

Best Publications

  • Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance

    Gina M. Leinninger;Darren M. Opland;Young Hwan Jo;Miro Faouzi

  • N-Terminal Phosphorylation of the Dopamine Transporter Is Required for Amphetamine-Induced Efflux

    Habibeh Khoshbouei;Namita Sen;Bipasha Guptaroy;L'Aurelle Johnson

  • Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates.

    Kim M. McGinnis;Margaret E. Gnegy;Yang Hae Park;Neeta Mukerjee

  • Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux

    Francesca Binda;Concetta Dipace;Erica Bowton;Sabrina D Robertson

  • Regulation of Amphetamine-stimulated Dopamine Efflux by Protein Kinase C β

    L'Aurelle A. Johnson;Bipasha Guptaroy;David Lund;Susanna Shamban

  • Effect of calmodulin on dopamine-sensitive adenylate cyclase activity in rat striatal membranes

    M. Gnegy;G. Treisman

  • Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation

    L'Aurelle A. Johnson;Cheryse A. Furman;Minjia Zhang;Bipasha Guptaroy

  • Protein Kinase C Inhibitors Block Amphetamine-Mediated Dopamine Release in Rat Striatal Slices

    Unknown

  • Protein Kinase Cβ Is a Critical Regulator of Dopamine Transporter Trafficking and Regulates the Behavioral Response to Amphetamine in Mice

    Rong Chen;Cheryse A. Furman;Minjia Zhang;Myung N. Kim

  • Calcium/Calmodulin-dependent Protein Kinase IV Is Cleaved by Caspase-3 and Calpain in SH-SY5Y Human Neuroblastoma Cells Undergoing Apoptosis

    Kim M. McGinnis;Margaret M. Whitton;Margaret E. Gnegy;Kevin K.W. Wang;Kevin K.W. Wang

  • Dopamine and Amphetamine Rapidly Increase Dopamine Transporter Trafficking to the Surface: Live-Cell Imaging Using Total Internal Reflection Fluorescence Microscopy

    Cheryse A. Furman;Rong Chen;Bipasha Guptaroy;Minjia Zhang

  • Enhanced Amphetamine- and K+-Mediated Dopamine Release in Rat Striatum after Repeated Amphetamine: Differential Requirements for Ca2+- and Calmodulin-Dependent Phosphorylation and Synaptic Vesicles

    L. Kantor;G. H. K. Hewlett;M. E. Gnegy

  • Intracellular Ca2+ regulates amphetamine-induced dopamine efflux and currents mediated by the human dopamine transporter

    Margaret E. Gnegy;Habibeh Khoshbouei;Kelly A. Berg;Jonathan A. Javitch

  • Alterations of extracellular calcium elicit selective modes of cell death and protease activation in SH-SY5Y human neuroblastoma cells

    Kim M. McGinnis;Kevin K. W. Wang;Kevin K. W. Wang;Margaret E. Gnegy

  • Enhanced Dopamine Release and Phosphorylation of Synapsin I and Neuromodulin in Striatal Synaptosomes after Repeated Amphetamine

    S.-I. Iwata;G. H. K. Hewlett;S. T. Ferrell;L. Kantor

  • Ca2+/calmodulin signaling in NMDA-induced synaptic plasticity.

    Gnegy Me

  • A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.

    Bipasha Guptaroy;Minjia Zhang;Erica Bowton;Francesca Binda

  • Calmodulin-Sensitive and Calmodulin-Insensitive Components of Adenylate Cyclase Activity in Rat Striatum Have Differential Responsiveness to Guanyl Nucleotides

    Glenn J. Treisman;Stuart Bagley;Margaret E. Gnegy

  • Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes

    Shin Ichi Iwata;G. H Keikilani Hewlett;Margaret E. Gnegy

  • Dopamine transporter antagonists block phorbol ester-induced dopamine release and dopamine transporter phosphorylation in striatal synaptosomes.

    Rita M Cowell;Lana Kantor;G.H.Keikilani Hewlett;Kirk A Frey

  • Protein Kinase C and Intracellular Calcium Are Required for Amphetamine-Mediated Dopamine Release via the Norepinephrine Transporter in Undifferentiated PC12 Cells

    L Kantor;G H Hewlett;Y H Park;S M Richardson-Burns

  • Participation of an endogenous Ca++-blinding protein activator in the development of drug-induced supersensitivity of striatal dopamine receptors.

    Unknown

Frequent Co-Authors

Terry E. Robinson
Terry E. Robinson University of Michigan–Ann Arbor
Eric K. Richfield
Eric K. Richfield Rutgers, The State University of New Jersey
Aldo Badiani
Aldo Badiani Sapienza University of Rome
Robert W. Gereau
Robert W. Gereau Washington University in St. Louis
Sara R. Jones
Sara R. Jones Wake Forest University
Kirk A. Frey
Kirk A. Frey University of Michigan–Ann Arbor
Robert P. Erickson
Robert P. Erickson University of Arizona
Brandon J. Aragona
Brandon J. Aragona University of Michigan–Ann Arbor
Daniel Goldman
Daniel Goldman University of Michigan–Ann Arbor
Jack M. Parent
Jack M. Parent University of Michigan–Ann Arbor

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