World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
99
Citations
53762
World Ranking
8426
National Ranking
4356

Overview

Paul K. Crane is affiliated with the University of Washington in the United States. Their research primarily falls within the broad field of Medicine, with significant contributions to several subfields including Psychiatry and Mental Health, Physiology, Molecular Biology, Genetics, and Neurology.

The scientist's work frequently addresses topics related to dementia and cognitive impairment research, Alzheimer's disease research and treatments, and genetic associations and epidemiology. Additional research themes include health disparities and outcomes, bioinformatics and genomic networks, health, environment, and cognitive aging, as well as frailty in older adults.

Paul K. Crane has contributed to numerous publications, including recent papers such as the 2020 study "Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study" published in Nature Communications. Also in 2020, the paper titled "Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel" appeared in JAMA Neurology. In 2021, the article "The Second NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy" was published in the Journal of Neuropathology & Experimental Neurology. More recently, in 2024, "Integrated multimodal cell atlas of Alzheimer's disease" was published in Nature Neuroscience. Additionally, the 2020 paper "Genetic variants and functional pathways associated with resilience to Alzheimer's disease" appeared in Brain.

Coauthorship is a notable aspect of their work, with frequent collaborators including Shubhabrata Mukherjee, Jesse Mez, Andrew J. Saykin, Emily H. Trittschuh, and Laura E. Gibbons. The publications have appeared mainly in journals such as Alzheimer's & Dementia, bioRxiv (Cold Spring Harbor Laboratory), Neurology, Journal of Alzheimer's Disease, and UNC Libraries.

Paul K. Crane's research output features 339 publications categorized under Medicine, with 99 in Psychiatry and Mental Health, 63 in Physiology, 53 in Molecular Biology, 52 in Genetics, and 34 in Neurology.

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Genetic Associations and Epidemiology
  • Health disparities and outcomes
  • Bioinformatics and Genomic Networks
  • Health, Environment, Cognitive Aging
  • Frailty in Older Adults

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2020), Nature Communications
  • The Second NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy (2021), Journal of Neuropathology & Experimental Neurology
  • Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel (2020), JAMA Neurology
  • Integrated multimodal cell atlas of Alzheimer's disease (2024), Nature Neuroscience
  • Genetic variants and functional pathways associated with resilience to Alzheimer's disease (2020), Brain

  • Shubhabrata Mukherjee
  • Jesse Mez
  • Andrew J. Saykin
  • Emily H. Trittschuh
  • Laura E. Gibbons

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Journal of Alzheimer's Disease
  • UNC Libraries

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older

    E. B. Larson;L. Wang;J. D. Bowen;W. C. McCormick

  • Association Between Obesity and Psychiatric Disorders in the US Adult Population

    Gregory E. Simon;Michael Von Korff;Kathleen Saunders;Diana L. Miglioretti;Diana L. Miglioretti

  • Psychometric evaluation and calibration of health-related quality of life item banks: plans for the Patient-Reported Outcomes Measurement Information System (PROMIS).

    Bryce B. Reeve;Ron D. Hays;Jakob B. Bjorner;Karon F. Cook

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

    Joshua C. Denny;Lisa Bastarache;Marylyn D. Ritchie;Robert J. Carroll

  • Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study.

    Shelly L. Gray;Melissa L. Anderson;Sascha Dublin;Joseph T. Hanlon

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Glucose Levels and Risk of Dementia

    Paul K. Crane;Rod Walker;Rebecca A. Hubbard;Ge Li

  • Chronic spinal pain and physical-mental comorbidity in the United States: results from the national comorbidity survey replication.

    Michael Von Korff;Paul Crane;Michael Lane;Diana L. Miglioretti

  • Development and assessment of a composite score for memory in the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

    Paul K. Crane;Adam Carle;Laura E. Gibbons;Philip Insel

  • Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia.

    Saion Chatterjee;Sanne A.E. Peters;Mark Woodward;Mark Woodward;Silvia Mejia Arango

  • Association Between Acute Care and Critical Illness Hospitalization and Cognitive Function in Older Adults

    William J. Ehlenbach;Catherine L. Hough;Paul K. Crane;Sebastien J. P. A. Haneuse

  • A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment

    Laura E. Gibbons;Adam C. Carle;R. Scott Mackin;Danielle J Harvey

  • Pathological correlates of dementia in a longitudinal, population-based sample of aging

    Joshua A. Sonnen;Eric B. Larson;Paul K. Crane;Sebastien Haneuse

  • Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

    Christiane Reitz;Gyungah Jun;Adam Naj;Ruchita Rajbhandary

  • Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies

    Laura A. Rabin;Laura A. Rabin;Laura A. Rabin;Colette M. Smart;Paul K. Crane;Rebecca E. Amariglio

  • Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

    Paul K. Crane;Laura E. Gibbons;Kristen Dams-O’Connor;Emily Trittschuh

  • The efficacy and safety of sibutramine for weight loss: a systematic review.

    David E. Arterburn;Paul K. Crane;David L. Veenstra

Frequent Co-Authors

Eric B. Larson
Eric B. Larson University of Washington
Thomas J. Montine
Thomas J. Montine Stanford University
Andrew J. Saykin
Andrew J. Saykin Indiana University
David A. Bennett
David A. Bennett Rush University Medical Center
Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Philip L. De Jager
Philip L. De Jager Columbia University
John S. K. Kauwe
John S. K. Kauwe Brigham Young University
Walter A. Kukull
Walter A. Kukull University of Washington
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Richard Mayeux
Richard Mayeux Columbia University

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