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Microbiology

D-Index
65
Citations
17101
World Ranking
2489
National Ranking
1009

Research.com Recognitions

  • 2008 - Fellow of the American Educational Research Association

Overview

Patricia M. Flynn is affiliated with St. Jude Children's Research Hospital in the United States. Their research primarily spans the field of Medicine, with a significant focus on Infectious Diseases, Emergency Medicine, Pediatrics, Perinatology and Child Health, Public Health, Environmental and Occupational Health, and Epidemiology.

The scientist's work covers several main topics, including:

  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • HIV-related health complications and treatments
  • Pharmacological Effects and Toxicity Studies
  • HIV Research and Treatment
  • Pregnancy and Medication Impact
  • Parasitic Infections and Diagnostics

Frequent publication venues for their research include:

  • JAIDS Journal of Acquired Immune Deficiency Syndromes
  • AIDS
  • UNC Libraries
  • The Lancet Infectious Diseases
  • The Lancet Neurology

Among their recent papers are:

  • "Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial" (2020, The Lancet Infectious Diseases)
  • "Association of Maternal Viral Load and CD4 Count With Perinatal HIV-1 Transmission Risk During Breastfeeding in the PROMISE Postpartum Component" (2021, JAIDS Journal of Acquired Immune Deficiency Syndromes)
  • "Safety and efficacy of arimoclomol for inclusion body myositis: a multicentre, randomised, double-blind, placebo-controlled trial" (2023, The Lancet Neurology)
  • "Maternal Human Immunodeficiency Virus (HIV) Drug Resistance Is Associated With Vertical Transmission and Is Prevalent in Infected Infants" (2021, Clinical Infectious Diseases)
  • "Combining SJ733, an oral ATP4 inhibitor of Plasmodium falciparum, with the pharmacokinetic enhancer cobicistat: An innovative approach in antimalarial drug development" (2022, EBioMedicine)

Flynn has worked frequently with several coauthors, including:

  • Mary Glenn Fowler
  • Dhayendre Moodley
  • Taha E. Taha
  • Maxensia Owor
  • Lynne Mofenson

Their scholarly contributions have resulted in multiple publications that enhance understanding in areas related to HIV/AIDS, maternal and child health, pharmacology, and parasitic diseases. The scientist was recognized as a Fellow of the American Educational Research Association in 2008.

Best Publications

  • Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter-Related Infection: 2009 Update by the Infectious Diseases Society of America

    Leonard A. Mermel;Michael Allon;Emilio Bouza;Donald E. Craven

  • Maternal Viral Load, Zidovudine Treatment, and the Risk of Transmission of Human Immunodeficiency Virus Type 1 from Mother to Infant

    Rhoda S. Sperling;David E. Shapiro;Robert W. Coombs;John A. Todd

  • MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs.

    John D. Schuetz;Michele C. Connelly;Daxi Sun;Sheela G. Paibir

  • Lack of Long-term Effects of In Utero Exposure to Zidovudine Among Uninfected Children Born to HIV-Infected Women

    Mary Culnane;Mary Glenn Fowler;Sophia S. Lee;George McSherry

  • Benefits and Risks of Antiretroviral Therapy for Perinatal HIV Prevention

    Mary G. Fowler;Min Qin;Susan A. Fiscus;Judith S. Currier

  • Micafungin (FK463), alone or in combination with other systemic antifungal agents, for the treatment of acute invasive aspergillosis *

    David W. Denning;Kieren A. Marr;Wendi M. Lau;David P. Facklam

  • Safety, tolerability, and pharmacokinetics of micafungin (FK463) in febrile neutropenic pediatric patients

    Nita L. Seibel;Cindy Schwartz;Antonio Arrieta;Patricia Flynn

  • Pharmacokinetics, Safety, and Tolerability of Caspofungin in Children and Adolescents

    Thomas J. Walsh;Peter C. Adamson;Nita L. Seibel;Patricia M. Flynn

  • Aspergillosis in Children with Cancer: A 34-Year Experience

    Seema Abbasi;Jerry L. Shenep;Walter T. Hughes;Patricia M. Flynn

  • Combination Therapy with Efavirenz, Nelfinavir, and Nucleoside Reverse-Transcriptase Inhibitors in Children Infected with Human Immunodeficiency Virus Type 1

    Stuart E. Starr;Courtney V. Fletcher;Stephen A. Spector;Florence H. Yong

  • Serial quantitation of endotoxemia and bacteremia during therapy for gram-negative bacterial sepsis.

    Jerry L. Shenep;Patricia M. Flynn;Frederick F. Barrett;Gregory L. Stidham

  • In situ management of confirmed central venous catheter-related bacteremia.

    Patricia M. Flynn;Jerry L. Shenep;Dennis C. Stokes;Fred F. Barrett

  • Prevention of HIV-1 Transmission Through Breastfeeding: Efficacy and Safety of Maternal Antiretroviral Therapy Versus Infant Nevirapine Prophylaxis for Duration of Breastfeeding in HIV-1-Infected Women With High CD4 Cell Count (IMPAACT PROMISE): A Randomized, Open-Label, Clinical Trial.

    Patricia M. Flynn;Taha E. Taha;Mae. Cababasay;Mary Glenn. Fowler

  • Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters.

    Ranga V. Srinivas;David Middlemas;Pat Flynn;Arnold Fridland

  • Typhlitis in Children with Cancer: A 30-Year Experience

    M. Melisse Sloas;Patricia M. Flynn;Sue C. Kaste;Christian C. Patrick

  • Bacillus cereus Bacteremia and Meningitis in Immunocompromised Children

    Aditya H. Gaur;Christian C. Patrick;Christian C. Patrick;Jon A. McCullers;Patricia M. Flynn;Patricia M. Flynn

  • Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza.

    Aditya H Gaur;Bindiya Bagga;Subrata Barman;Randall Hayden

  • First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial.

    Linda Harrison;Abdel Babiker;Hannah Castro;Alexandra Compagnucci

  • Population Pharmacokinetics of Micafungin in Pediatric Patients and Implications for Antifungal Dosing

    William W. Hope;Nita L. Seibel;Cindy L. Schwartz;Antonio Arrieta

  • Virologic and Immunologic Outcomes after 24 Weeks in HIV Type 1-Infected Adolescents Receiving Highly Active Antiretroviral Therapy

    PM Flynn;BJ Rudy;SD Douglas;J Lathey

Frequent Co-Authors

Jerry L. Shenep
Jerry L. Shenep St. Jude Children's Research Hospital
Stephen A. Spector
Stephen A. Spector University of California, San Diego
Walter T. Hughes
Walter T. Hughes St. Jude Children's Research Hospital
Ching-Hon Pui
Ching-Hon Pui St. Jude Children's Research Hospital
Craig M. Wilson
Craig M. Wilson University of Alabama at Birmingham
Lynne M. Mofenson
Lynne M. Mofenson Elizabeth Glaser Pediatric AIDS Foundation
Jonathan A. McCullers
Jonathan A. McCullers University of Tennessee Health Science Center
Nigel Curtis
Nigel Curtis Royal Children's Hospital
Charles B. Stephensen
Charles B. Stephensen United States Department of Agriculture
Mary Glenn Fowler
Mary Glenn Fowler Johns Hopkins University

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